ID.41

PUTATIVE SAM-DEPENDENT RNA METHYLTRANSFERASE

PDB

The ligand-free form

1wxx_CD [Alignment: 1 2]

The ligand-bound form

2cww_BB[Alignment: 1 2]

View

Animations of

the structural change


Using Jmol

Ligand

PDB*1

Full name

2xSAH

2x(S-ADENOSYL-L-HOMOCYSTEINE)

*1 Ligand name designated by the PDB identifiers.

Segments

Component No.

Fixed*1

Moving*1

Motion type

Ligand binding

Coupled motion type

1

D1(3B-344B,351B-382B,1B-1B,25B-44B,47B-56B,63B-69B,93B-94B,173B-175B,184B-195B,203B-205B,209B-221B,229B-243B,261B-357B,373B-380B)

D2(345B-350B,2B-24B,45B-46B,57B-62B,70B-92B,95B-172B,176B-183B,196B-202B,206B-208B,222B-228B,244B-258B,358B-372B)

Domain

Independent

*1 The location of the fixed and moving segments indicated by the residue number assigned in the ligand-bound form. The background color of characters indicates the corresponding segment in the structure. The colored segments not described in the Table are: 1) a part of component in which the motion is small (< 1.0 A), or, 2) a part of a protomer of homodimers, for which a corresponding part of the other protomer is shown in the Table.

Displacement and disorder

Component No.

RMSD*1

Displacement*2

Disorder-order transition*3

Disorder residue*4

Helix-Coil*5

1

1.2

*1 The root-mean-square displacement of a component of motion calculated for the domain motions.
*2 The mean displacement of a component of motion calculated for the local motions.
*3 Order-disorder transition: Whether the open form contains the disordered structure.
*4 The number of disordered residues.
*5 The number of residues exhibiting the alpha-helix to coil transition.

Crystal environment

Component No.

Open state*1

Crystal packing*2

1

Bound

Coupled

*1 Distinction between the open state and the closed state required for examining the influence of the crystal environment.
*2 Crystal packing: Whether the change in the crystal environment is coupled with the structural change.

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