IL.108

ACETYL-COENZYME A CARBOXYLASE

PDB

The ligand-free form

1od4_AA [Alignment: 1 2]

The ligand-bound form

1od2_AB[Alignment: 1 2]

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the structural change


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Function

EC*1

CSA distance*2

6.4.1.2

3.3

*1 Enzyme commission number.
*2 The distance between the active site annotated in CSA23 and the ligand-binding sites.

Ligand

PDB*1

Full name

ACO,ADE

ACETYL COENZYME *A,ADENINE

*1 Ligand name designated by the PDB identifiers.

Segments

Component No.

Fixed*1

Moving*1

Motion type

Ligand binding

Coupled motion type

1

D1(1486A-1643A,1649A-2047A,2082A-2129A,2158A-2161A,2167A-2171A,2173A-2174A,1496B-1645B,1652B-2047B,2082B-2187B)

L2(2048A-2081A)

Local

Independent

*1 The location of the fixed and moving segments indicated by the residue number assigned in the ligand-bound form. The background color of characters indicates the corresponding segment in the structure. The colored segments not described in the Table are: 1) a part of component in which the motion is small (< 1.0 A), or, 2) a part of a protomer of homodimers, for which a corresponding part of the other protomer is shown in the Table.

Displacement and disorder

Component No.

RMSD*1

Displacement*2

Disorder-order transition*3

Disorder residue*4

Helix-Coil*5

1

Yes

+33

*1 The root-mean-square displacement of a component of motion calculated for the domain motions.
*2 The mean displacement of a component of motion calculated for the local motions.
*3 Order-disorder transition: Whether the open form contains the disordered structure.
*4 The number of disordered residues.
*5 The number of residues exhibiting the alpha-helix to coil transition.

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