IL.59

BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN

PDB

The ligand-free form

1t2u_A [Alignment: 1]

The ligand-bound form

1t15_A[Alignment: 1]

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the structural change


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Ligand

PDB*1

Full name

PEPT(STSPTFNK)

Peptide(STSPTFNK)

*1 Ligand name designated by the PDB identifiers.

Segments

Component No.

Fixed*1

Moving*1

Motion type

Ligand binding

Coupled motion type

1

D1(1651A-1655A,1676A-1815A,1821A-1857A)

L2(1816A-1820A)

Local

Independent

*1 The location of the fixed and moving segments indicated by the residue number assigned in the ligand-bound form. The background color of characters indicates the corresponding segment in the structure. The colored segments not described in the Table are: 1) a part of component in which the motion is small (< 1.0 A), or, 2) a part of a protomer of homodimers, for which a corresponding part of the other protomer is shown in the Table.

Displacement and disorder

Component No.

RMSD*1

Displacement*2

Disorder-order transition*3

Disorder residue*4

Helix-Coil*5

1

Yes

+4

*1 The root-mean-square displacement of a component of motion calculated for the domain motions.
*2 The mean displacement of a component of motion calculated for the local motions.
*3 Order-disorder transition: Whether the open form contains the disordered structure.
*4 The number of disordered residues.
*5 The number of residues exhibiting the alpha-helix to coil transition.

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