B.19

LIPOATE-PROTEIN LIGASE A

PDB

The ligand-free form

2c7i_A [Alignment: 1]

The ligand-bound form

2art_A[Alignment: 1]

View

Animations of

the structural change


Using Jmol

Function

EC*1

CSA distance*2

2.7.7.63

*1 Enzyme commission number.
*2 The distance between the active site annotated in CSA23 and the ligand-binding sites.

Ligand

PDB*1

Full name

AMP,LPA,MG

ADENOSINE MONOPHOSPHATE,LIPOIC ACID,MAGNESIUM ION

*1 Ligand name designated by the PDB identifiers.

Segments

Component No.

Fixed*1

Moving*1

Motion type

Ligand binding

Coupled motion type

1

Buried ligand

*1 The location of the fixed and moving segments indicated by the residue number assigned in the ligand-bound form. The background color of characters indicates the corresponding segment in the structure. The colored segments not described in the Table are: 1) a part of component in which the motion is small (< 1.0 A), or, 2) a part of a protomer of homodimers, for which a corresponding part of the other protomer is shown in the Table.

H-bond

Component No.

Ligand*1

Water*1

Protein*1

1

10

3

4

*1 The number of hydrogen-bonds observed in the proteins classified in "Buried Ligand".

Link ::.