N.1

EPIDERMAL GROWTH FACTOR RECEPTOR

PDB

The ligand-free form

1m14_A [Alignment: 1]

The ligand-bound form

2itp_A[Alignment: 1]

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Function

EC*1

CSA distance*2

2.7.10.1

6.4

*1 Enzyme commission number.
*2 The distance between the active site annotated in CSA23 and the ligand-binding sites.

Ligand

PDB*1

Full name

AEE

6-{4-[(4-ETHYLPIPERAZIN-1-YL)METHYL]PHENYL}-N-[(1R)-1-HENYLETHYL]-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE

*1 Ligand name designated by the PDB identifiers.

Segments

Component No.

Fixed*1

Moving*1

Motion type

Ligand binding

Coupled motion type

1

No significant

*1 The location of the fixed and moving segments indicated by the residue number assigned in the ligand-bound form. The background color of characters indicates the corresponding segment in the structure. The colored segments not described in the Table are: 1) a part of component in which the motion is small (< 1.0 A), or, 2) a part of a protomer of homodimers, for which a corresponding part of the other protomer is shown in the Table.

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