Beclin-1
type: Protein
pdb date: 2018-08-03
uniprot date: 2018-04-25
ideal date: 2021-08-01
organism: Mus musculus
seq len: 448
uniprot id: O88597
motif: BH3
  region: Region
    begin: ExactPosition
      position: 106
      reference: O88597-1
    end: ExactPosition
      position: 125
      reference: O88597-1
modification: N-acetylmethionine
  modification region: Region
    begin: ExactPosition
      position: 1
      reference: O88597-1
    end: ExactPosition
      position: 1
      reference: O88597-1
modification: Phosphoserine
  modification region: Region
    begin: ExactPosition
      position: 29
      reference: O88597-1
    end: ExactPosition
      position: 29
      reference: O88597-1
modification: Phosphoserine; by AMPK
  modification region: Region
    begin: ExactPosition
      position: 88
      reference: O88597-1
    end: ExactPosition
      position: 88
      reference: O88597-1
modification: Phosphoserine; by AMPK
  modification region: Region
    begin: ExactPosition
      position: 91
      reference: O88597-1
    end: ExactPosition
      position: 91
      reference: O88597-1
modification: Phosphoserine; by AMPK
  modification region: Region
    begin: ExactPosition
      position: 94
      reference: O88597-1
    end: ExactPosition
      position: 94
      reference: O88597-1
modification: Phosphothreonine; by DAPK1
  modification region: Region
    begin: ExactPosition
      position: 117
      reference: O88597-1
    end: ExactPosition
      position: 117
      reference: O88597-1
sequence: MEGSKASSSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEEEANSGEEPFIETRQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQRELKELALEEERLIQELEDVEKNRKVVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQVRYAQIQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFFWDNKFDHAMVAFLDCVQQFKEEVEKGETRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQWTKALKFMLTNLKWGLAWVSSQFYNK
region: 1
region: 2
condition: 1
pros: 1

1
type: Region
range: Region
  begin: ExactPosition
    position: 106
    reference: O88597-1
  end: ExactPosition
    position: 124
    reference: O88597-1
pdb id: 3BL2
chain id: C
condition: 1

2
type: Region
range: Region
  begin: ExactPosition
    position: 106
    reference: O88597-1
  end: ExactPosition
    position: 124
    reference: O88597-1
pdb id: 3BL2
chain id: D
condition: 1

1
pdb id: 3BL2
crystalization temperature: 298K
crystalization p h: 7
pubmed id: https://pubmed.ncbi.nlm.nih.gov/18248095
missing:
  chain: C
  begin: ExactPosition
    position: 106
    reference: O88597-1
  end: ExactPosition
    position: 124
    reference: O88597-1
  identity: 100
  missing number: 0
missing:
  chain: D
  begin: ExactPosition
    position: 106
    reference: O88597-1
  end: ExactPosition
    position: 124
    reference: O88597-1
  identity: 100
  missing number: 0
  chain: 3bl2C
  chain: 3bl2A
  chain: 3bl2D
  chain: 3bl2B
biological unit: 1
biological unit: 2

1
oligomeric state: Hetero dimer
chain:
  uniprot id: O88597
  idp id: Beclin-1
chain:
  uniprot id: P89884
interaction:
  interact: C
  interact: A

2
oligomeric state: Hetero dimer
chain:
  uniprot id: O88597
  idp id: Beclin-1
chain:
  uniprot id: P89884
interaction:
  interact: D
  interact: B

1
pros type: possible
order region id: 1
order region id: 2
order range:
  begin: ExactPosition
    position: 106
    reference: O88597-1
  end: ExactPosition
    position: 124
    reference: O88597-1

order: Region
  begin: ExactPosition
    position: 16
    reference: O88597-1
  end: ExactPosition
    position: 24
    reference: O88597-1
order: Region
  begin: ExactPosition
    position: 121
    reference: O88597-1
  end: ExactPosition
    position: 122
    reference: O88597-1
order: Region
  begin: ExactPosition
    position: 125
    reference: O88597-1
  end: ExactPosition
    position: 125
    reference: O88597-1
order: Region
  begin: ExactPosition
    position: 131
    reference: O88597-1
  end: ExactPosition
    position: 131
    reference: O88597-1
order: Region
  begin: ExactPosition
    position: 133
    reference: O88597-1
  end: ExactPosition
    position: 169
    reference: O88597-1
order: Region
  begin: ExactPosition
    position: 174
    reference: O88597-1
  end: ExactPosition
    position: 354
    reference: O88597-1
order: Region
  begin: ExactPosition
    position: 360
    reference: O88597-1
  end: ExactPosition
    position: 383
    reference: O88597-1
order: Region
  begin: ExactPosition
    position: 387
    reference: O88597-1
  end: ExactPosition
    position: 445
    reference: O88597-1
disorder: Region
  begin: ExactPosition
    position: 1
    reference: O88597-1
  end: ExactPosition
    position: 15
    reference: O88597-1
disorder: Region
  begin: ExactPosition
    position: 25
    reference: O88597-1
  end: ExactPosition
    position: 120
    reference: O88597-1
disorder: Region
  begin: ExactPosition
    position: 123
    reference: O88597-1
  end: ExactPosition
    position: 124
    reference: O88597-1
disorder: Region
  begin: ExactPosition
    position: 126
    reference: O88597-1
  end: ExactPosition
    position: 130
    reference: O88597-1
disorder: Region
  begin: ExactPosition
    position: 132
    reference: O88597-1
  end: ExactPosition
    position: 132
    reference: O88597-1
disorder: Region
  begin: ExactPosition
    position: 170
    reference: O88597-1
  end: ExactPosition
    position: 173
    reference: O88597-1
disorder: Region
  begin: ExactPosition
    position: 355
    reference: O88597-1
  end: ExactPosition
    position: 359
    reference: O88597-1
disorder: Region
  begin: ExactPosition
    position: 384
    reference: O88597-1
  end: ExactPosition
    position: 386
    reference: O88597-1
disorder: Region
  begin: ExactPosition
    position: 446
    reference: O88597-1
  end: ExactPosition
    position: 448
    reference: O88597-1