20210801 20180803 20180228 20210801 IID50154 Retinoic acid receptor RXR RXR-like protein Retinoid X receptor Biomphalaria glabrata 436 Q8T5C6 Ligand-dependent transcription factor probably involved in the retinoic acid response pathway. Binds 9-cis-retinoic acid (9C-RA) and, to a lesser extent, docosahexaenoic acid (DHA), phytanic acid, methoprene acid and oleic acid. Binds to double-stranded DNA sequences containing direct repeats (DR) with the consensus sequence 5'-[AG]GGTCA-3' and 1, 2, 3, 4 or 5 nucleotides in between (DR1, DR2, DR3. DR4 and DR5, respectively). Binding to DR1 is strongest. Transactivates gene expression when 9C-RA or DHA is bound. Membrane, Coated pit. SL-0072 unkown Cell membrane. SL-0039 unkown 0 0 0 0 RXR RXR_BIOGL MDRSEGMDTLENSMPSGMSMGMTMGGHQGHPPPDIKPDISSLTSPTSTHGYYGFGPGGMPSMASSTQPSPGPQQMHSPGMHSPTSSMGSPPMLCLSPSGPSPSPGLPHSSLHTKHICAICGDRASGKHYGVYSCEGCKGFFKRTVRKDLTYACRDDKNCMIDKRQRNRCQYCRYMKCLSMGMKREAVQEERQRVKEKGDGEVESTSGANNDMPVEQILEAELAVDPKIDTYIDAQKDPVTNICQAADKQLFTLVEWAKRIPHFTELPLEDQVILLRAGWNELLIAGFSHRSIMAKDGILLATGLHVHRSSAHQAGVGTIFDRVLTELVAKMRDMKMDKTELGCLRAVVLFNPDAKGLTAVQEVEQLREKVYASLEEYTKSRYPEEPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDQPIDTFLMEMLENPSPAT 1 1xiuA 207 209 disorder 1 2 1xiuA 210 430 order 1 3 1xiuA 431 436 disorder 1 4 1xiuB 207 208 disorder 1 5 1xiuB 209 432 order 1 6 1xiuB 433 436 disorder 1 1 1xiu X-RAY 293K 7.5 16274693 A.DE GROOT,E.DE ROSNY,C.JUILLAN-BINARD,J.-L.FERRER,V.LAUDET,R.J.PIERCE,E.PEBAY-PEYROULA,J.-C.FONTECILLA-CAMPS,F.BOREL 2005 J.MOL.BIOL. 354 841 x-ray 1xiu A 207 436 100 2 207 209 431 436 x-ray 1xiu B 207 436 100 2 207 208 433 436 1 1xiu_1 3333 Hetero octamer 1xiuF Q15788 IID00083 1xiuE Q15788 IID00083 1xiuB Q8T5C6 IID50154 1xiuA Q8T5C6 IID50154 1xiuF-1xiuB 1xiuE-1xiuA 1xiuB-1xiuA 1xiuA-1xiuA 114-191,210-228,237-414,423-423,427-428 1-113,192-209,229-236,415-422,424-426,429-436 114-184,213-433 1-113,185-212,434-436 4-12,33-38,185-194,434-436 13-33,85-112