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IID00011
 UniprotO95718
ProteinSteroid hormone receptor ERR2
GeneESRRB
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
433
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 97-192 Monomer :
 Evidence NMR 1lo1 A Reference
       Region 1lo1 A 97-186 order
       Region 1lo1 A 97-99 high_rmsd
       Region 1lo1 A 187-192 disorder
Seqdisorder 169-186
 Evidence NMR Reference
       Region 169-186 disorder
SeqProS verified 169-186 This region is ordered when it binds upon DNA. :
       Region 1lo1 A 97-186 order
       Region 169-186 disorder
 
Prediction
NeProc
Disorder 1-99,180-208
Order 100-179,209-433
ProS 6-24,44-47
AlphaFold
Disorder 1-100,176-210
Order 101-175,211-433
Pfam Hmmer
PF00105 101-176 6.2e-51
PF00104 248-428 1.7e-56
SEG 28-50 ,392-399
Function
Function in SwissProt
Isoform 1
Transcription factor that binds a canonical ESRRB recognition (ERRE) sequence 5'TCAAGGTCA-3' localized on promoter and enhancer of targets genes regulating their expression or their transcription activity. Positively regaulate ESR1 transcriptional activity upon E2 stimulation.