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IID00013
UniprotP03372
ProteinEstrogen receptor
GeneESR1
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
595
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seqdisorder 1-184
 Evidence NMR Reference
       Region 1-184 disorder
Seqdisorder 1-184
 Evidence CD Reference
       Region 1-184 disorder
Seq 180-254 Monomer :
 Evidence NMR 1hcp A Reference
       Region 1hcp A 180-253 order
       Region 1hcp A 180-180 high_rmsd
       Region 1hcp A 222-225 high_rmsd
       Region 1hcp A 254-254 disorder
Seq 180-262 Homo dimer :
 Evidence X-RAY 1hcq F Reference
       Region 1hcq F 180-215 order
       Region 1hcq F 216-217 disorder
       Region 1hcq F 218-252 order
       Region 1hcq F 253-262 disorder
 Evidence X-RAY 1hcq E Reference
       Region 1hcq E 180-252 order
       Region 1hcq E 253-262 disorder
 Evidence X-RAY 1hcq B Reference
       Region 1hcq B 180-181 disorder
       Region 1hcq B 182-252 order
       Region 1hcq B 253-262 disorder
 Evidence X-RAY 1hcq A Reference
       Region 1hcq A 180-252 order
       Region 1hcq A 253-262 disorder
 Evidence X-RAY 4aa6 F Reference
       Region 4aa6 F 182-231 order
       Region 4aa6 F 232-233 disorder
       Region 4aa6 F 234-252 order
 Evidence X-RAY 4aa6 E Reference
       Region 4aa6 E 182-182 disorder
       Region 4aa6 E 183-215 order
       Region 4aa6 E 216-217 disorder
       Region 4aa6 E 218-252 order
 Evidence X-RAY 4aa6 B Reference
       Region 4aa6 B 182-216 order
       Region 4aa6 B 217-217 disorder
       Region 4aa6 B 218-252 order
 Evidence X-RAY 4aa6 A Reference
       Region 4aa6 A 182-213 order
       Region 4aa6 A 214-215 disorder
       Region 4aa6 A 216-252 order
Seqdisorder 220-236
 Evidence NMR This region is disordered without DNA. Reference
       Region 220-236 disorder
Seq 261-271 Hetero dimer : IID00329Complex
 Evidence X-RAY 4o6f B Reference
       Region 4o6f B 261-261 disorder
       Region 4o6f B 262-271 order
Seq 287-305 Hetero dimer : IID50309Complex
 Evidence NMR 2llo B Reference
       Region 2llo B 287-305 order
Seq 287-305 Hetero trimer : IID50309Complex
 Evidence NMR 5t0x C Reference
       Region 5t0x C 287-305 order
 Evidence NMR 5t0x B Reference
       Region 5t0x B 287-305 order
Seq 287-305 Hetero dimer : IID50309Complex
 Evidence NMR 2llq B Reference
       Region 2llq B 287-305 order
Seq 297-554 Hetero dimer : IID00082Complex
 Evidence X-RAY 3q95 B Reference
       Region 3q95 B 298-299 disorder
       Region 3q95 B 300-552 order
       Region 3q95 B 553-554 disorder
 Evidence X-RAY 3q95 A Reference
       Region 3q95 A 298-304 disorder
       Region 3q95 A 305-463 order
       Region 3q95 A 464-465 disorder
       Region 3q95 A 466-550 order
       Region 3q95 A 551-554 disorder
 Evidence X-RAY 4q13 B Reference
       Region 4q13 B 299-305 disorder
       Region 4q13 B 306-331 order
       Region 4q13 B 332-336 disorder
       Region 4q13 B 337-460 order
       Region 4q13 B 461-471 disorder
       Region 4q13 B 472-532 order
       Region 4q13 B 533-533 disorder
       Region 4q13 B 534-548 order
       Region 4q13 B 549-554 disorder
 Evidence X-RAY 4q13 A Reference
       Region 4q13 A 299-305 disorder
       Region 4q13 A 306-336 order
       Region 4q13 A 337-337 disorder
       Region 4q13 A 338-418 order
       Region 4q13 A 419-419 disorder
       Region 4q13 A 420-460 order
       Region 4q13 A 461-472 disorder
       Region 4q13 A 473-532 order
       Region 4q13 A 533-535 disorder
       Region 4q13 A 536-548 order
       Region 4q13 A 549-554 disorder
 Evidence X-RAY 5kd9 B Reference
       Region 5kd9 B 298-304 disorder
       Region 5kd9 B 303-304 disorder
       Region 5kd9 B 305-460 order
       Region 5kd9 B 461-469 disorder
       Region 5kd9 B 470-527 order
       Region 5kd9 B 528-533 disorder
       Region 5kd9 B 534-547 order
       Region 5kd9 B 548-554 disorder
       Region 5kd9 B 548-549 disorder
 Evidence X-RAY 5kd9 A Reference
       Region 5kd9 A 298-304 disorder
       Region 5kd9 A 303-304 disorder
       Region 5kd9 A 305-461 order
       Region 5kd9 A 462-470 disorder
       Region 5kd9 A 471-548 order
       Region 5kd9 A 549-554 disorder
       Region 5kd9 A 549-549 disorder
 Evidence X-RAY 5kcw B Reference
       Region 5kcw B 298-304 disorder
       Region 5kcw B 303-304 disorder
       Region 5kcw B 305-416 order
       Region 5kcw B 417-419 disorder
       Region 5kcw B 420-460 order
       Region 5kcw B 461-469 disorder
       Region 5kcw B 470-526 order
       Region 5kcw B 527-534 disorder
       Region 5kcw B 535-548 order
       Region 5kcw B 549-554 disorder
       Region 5kcw B 549-549 disorder
 Evidence X-RAY 5kcw A Reference
       Region 5kcw A 298-303 disorder
       Region 5kcw A 303-303 disorder
       Region 5kcw A 304-331 order
       Region 5kcw A 332-333 disorder
       Region 5kcw A 334-461 order
       Region 5kcw A 462-471 disorder
       Region 5kcw A 472-548 order
       Region 5kcw A 549-554 disorder
       Region 5kcw A 549-549 disorder
 Evidence X-RAY 5kcu B Reference
       Region 5kcu B 298-304 disorder
       Region 5kcu B 303-304 disorder
       Region 5kcu B 305-460 order
       Region 5kcu B 461-467 disorder
       Region 5kcu B 468-527 order
       Region 5kcu B 528-534 disorder
       Region 5kcu B 535-545 order
       Region 5kcu B 546-554 disorder
       Region 5kcu B 546-548 disorder
 Evidence X-RAY 5kcu A Reference
       Region 5kcu A 298-305 disorder
       Region 5kcu A 303-305 disorder
       Region 5kcu A 306-331 order
       Region 5kcu A 332-335 disorder
       Region 5kcu A 336-461 order
       Region 5kcu A 462-471 disorder
       Region 5kcu A 472-532 order
       Region 5kcu A 533-535 disorder
       Region 5kcu A 536-548 order
       Region 5kcu A 549-554 disorder
 Evidence X-RAY 5kct B Reference
       Region 5kct B 298-305 disorder
       Region 5kct B 303-305 disorder
       Region 5kct B 306-416 order
       Region 5kct B 417-420 disorder
       Region 5kct B 421-461 order
       Region 5kct B 462-467 disorder
       Region 5kct B 468-526 order
       Region 5kct B 527-533 disorder
       Region 5kct B 534-548 order
       Region 5kct B 549-554 disorder
 Evidence X-RAY 5kct A Reference
       Region 5kct A 298-302 disorder
       Region 5kct A 303-461 order
       Region 5kct A 462-471 disorder
       Region 5kct A 472-548 order
       Region 5kct A 549-554 disorder
 Evidence X-RAY 5kcf B Reference
       Region 5kcf B 298-304 disorder
       Region 5kcf B 303-304 disorder
       Region 5kcf B 305-414 order
       Region 5kcf B 415-420 disorder
       Region 5kcf B 421-461 order
       Region 5kcf B 462-465 disorder
       Region 5kcf B 466-527 order
       Region 5kcf B 528-534 disorder
       Region 5kcf B 535-548 order
       Region 5kcf B 549-554 disorder
       Region 5kcf B 549-549 disorder
 Evidence X-RAY 5kcf A Reference
       Region 5kcf A 298-302 disorder
       Region 5kcf A 303-460 order
       Region 5kcf A 461-471 disorder
       Region 5kcf A 472-549 order
       Region 5kcf A 550-554 disorder
 Evidence X-RAY 5kcd B Reference
       Region 5kcd B 298-304 disorder
       Region 5kcd B 305-331 order
       Region 5kcd B 332-336 disorder
       Region 5kcd B 337-456 order
       Region 5kcd B 457-469 disorder
       Region 5kcd B 470-548 order
       Region 5kcd B 549-554 disorder
       Region 5kcd B 549-549 disorder
 Evidence X-RAY 5kcd A Reference
       Region 5kcd A 298-304 disorder
       Region 5kcd A 305-459 order
       Region 5kcd A 460-472 disorder
       Region 5kcd A 473-548 order
       Region 5kcd A 549-554 disorder
       Region 5kcd A 549-549 disorder
 Evidence X-RAY 5kcc B Reference
       Region 5kcc B 298-303 disorder
       Region 5kcc B 304-331 order
       Region 5kcc B 332-336 disorder
       Region 5kcc B 337-460 order
       Region 5kcc B 461-472 disorder
       Region 5kcc B 473-529 order
       Region 5kcc B 530-531 disorder
       Region 5kcc B 532-549 order
       Region 5kcc B 550-554 disorder
 Evidence X-RAY 5kcc A Reference
       Region 5kcc A 298-304 disorder
       Region 5kcc A 304-304 disorder
       Region 5kcc A 305-460 order
       Region 5kcc A 461-467 disorder
       Region 5kcc A 468-548 order
       Region 5kcc A 549-554 disorder
       Region 5kcc A 549-549 disorder
 Evidence X-RAY 4iwf B Reference
       Region 4iwf B 303-305 disorder
       Region 4iwf B 306-332 order
       Region 4iwf B 333-336 disorder
       Region 4iwf B 337-460 order
       Region 4iwf B 461-471 disorder
       Region 4iwf B 472-548 order
       Region 4iwf B 549-549 disorder
 Evidence X-RAY 4iwf A Reference
       Region 4iwf A 303-304 disorder
       Region 4iwf A 305-461 order
       Region 4iwf A 462-469 disorder
       Region 4iwf A 470-548 order
       Region 4iwf A 549-549 disorder
 Evidence X-RAY 4iwc B Reference
       Region 4iwc B 303-304 disorder
       Region 4iwc B 305-462 order
       Region 4iwc B 463-464 disorder
       Region 4iwc B 465-531 order
       Region 4iwc B 532-534 disorder
       Region 4iwc B 535-549 order
 Evidence X-RAY 4iwc A Reference
       Region 4iwc A 303-304 disorder
       Region 4iwc A 305-461 order
       Region 4iwc A 462-469 disorder
       Region 4iwc A 470-548 order
       Region 4iwc A 549-549 disorder
 Evidence X-RAY 4iw8 B Reference
       Region 4iw8 B 303-303 disorder
       Region 4iw8 B 304-460 order
       Region 4iw8 B 461-472 disorder
       Region 4iw8 B 473-548 order
       Region 4iw8 B 549-549 disorder
 Evidence X-RAY 4iw8 A Reference
       Region 4iw8 A 303-304 disorder
       Region 4iw8 A 305-418 order
       Region 4iw8 A 419-420 disorder
       Region 4iw8 A 421-461 order
       Region 4iw8 A 462-464 disorder
       Region 4iw8 A 465-548 order
       Region 4iw8 A 549-549 disorder
 Evidence X-RAY 4iw6 B Reference
       Region 4iw6 B 303-304 disorder
       Region 4iw6 B 305-414 order
       Region 4iw6 B 415-417 disorder
       Region 4iw6 B 418-461 order
       Region 4iw6 B 462-467 disorder
       Region 4iw6 B 468-548 order
       Region 4iw6 B 549-549 disorder
 Evidence X-RAY 4iw6 A Reference
       Region 4iw6 A 303-303 disorder
       Region 4iw6 A 304-460 order
       Region 4iw6 A 461-472 disorder
       Region 4iw6 A 473-548 order
       Region 4iw6 A 549-549 disorder
 Evidence X-RAY 4ivy B Reference
       Region 4ivy B 303-304 disorder
       Region 4ivy B 305-415 order
       Region 4ivy B 416-420 disorder
       Region 4ivy B 421-460 order
       Region 4ivy B 461-467 disorder
       Region 4ivy B 468-548 order
       Region 4ivy B 549-549 disorder
 Evidence X-RAY 4ivy A Reference
       Region 4ivy A 303-303 disorder
       Region 4ivy A 304-414 order
       Region 4ivy A 415-417 disorder
       Region 4ivy A 418-459 order
       Region 4ivy A 460-472 disorder
       Region 4ivy A 473-548 order
       Region 4ivy A 549-549 disorder
 Evidence X-RAY 4ivw B Reference
       Region 4ivw B 303-303 disorder
       Region 4ivw B 304-415 order
       Region 4ivw B 416-417 disorder
       Region 4ivw B 418-461 order
       Region 4ivw B 462-466 disorder
       Region 4ivw B 467-548 order
       Region 4ivw B 549-549 disorder
 Evidence X-RAY 4ivw A Reference
       Region 4ivw A 303-460 order
       Region 4ivw A 461-472 disorder
       Region 4ivw A 473-548 order
       Region 4ivw A 549-549 disorder
 Evidence X-RAY 4iv4 B Reference
       Region 4iv4 B 303-304 disorder
       Region 4iv4 B 305-416 order
       Region 4iv4 B 417-420 disorder
       Region 4iv4 B 421-458 order
       Region 4iv4 B 459-466 disorder
       Region 4iv4 B 467-548 order
       Region 4iv4 B 549-549 disorder
 Evidence X-RAY 4iv4 A Reference
       Region 4iv4 A 303-304 disorder
       Region 4iv4 A 305-329 order
       Region 4iv4 A 330-333 disorder
       Region 4iv4 A 334-461 order
       Region 4iv4 A 462-471 disorder
       Region 4iv4 A 472-532 order
       Region 4iv4 A 533-533 disorder
       Region 4iv4 A 534-548 order
       Region 4iv4 A 549-549 disorder
 Evidence X-RAY 4iv2 B Reference
       Region 4iv2 B 303-304 disorder
       Region 4iv2 B 305-413 order
       Region 4iv2 B 414-415 disorder
       Region 4iv2 B 416-459 order
       Region 4iv2 B 460-463 disorder
       Region 4iv2 B 464-548 order
       Region 4iv2 B 549-549 disorder
 Evidence X-RAY 4iv2 A Reference
       Region 4iv2 A 303-304 disorder
       Region 4iv2 A 305-459 order
       Region 4iv2 A 460-472 disorder
       Region 4iv2 A 473-548 order
       Region 4iv2 A 549-549 disorder
 Evidence X-RAY 4iui B Reference
       Region 4iui B 303-307 disorder
       Region 4iui B 308-335 order
       Region 4iui B 336-339 disorder
       Region 4iui B 340-412 order
       Region 4iui B 413-420 disorder
       Region 4iui B 421-460 order
       Region 4iui B 461-469 disorder
       Region 4iui B 470-549 order
 Evidence X-RAY 4iui A Reference
       Region 4iui A 303-304 disorder
       Region 4iui A 305-330 order
       Region 4iui A 331-338 disorder
       Region 4iui A 339-416 order
       Region 4iui A 417-420 disorder
       Region 4iui A 421-459 order
       Region 4iui A 460-474 disorder
       Region 4iui A 475-530 order
       Region 4iui A 531-536 disorder
       Region 4iui A 537-548 order
       Region 4iui A 549-549 disorder
 Evidence X-RAY 4iu7 B Reference
       Region 4iu7 B 303-304 disorder
       Region 4iu7 B 305-413 order
       Region 4iu7 B 414-415 disorder
       Region 4iu7 B 416-459 order
       Region 4iu7 B 460-465 disorder
       Region 4iu7 B 466-549 order
 Evidence X-RAY 4iu7 A Reference
       Region 4iu7 A 303-303 disorder
       Region 4iu7 A 304-461 order
       Region 4iu7 A 462-471 disorder
       Region 4iu7 A 472-548 order
       Region 4iu7 A 549-549 disorder
 Evidence X-RAY 1gwq B Reference
       Region 1gwq B 301-330 order
       Region 1gwq B 331-336 disorder
       Region 1gwq B 337-548 order
 Evidence X-RAY 1gwq A Reference
       Region 1gwq A 301-330 order
       Region 1gwq A 331-335 disorder
       Region 1gwq A 336-548 order
 Evidence X-RAY 5dxg B Reference
       Region 5dxg B 297-307 disorder
       Region 5dxg B 308-330 order
       Region 5dxg B 331-336 disorder
       Region 5dxg B 337-457 order
       Region 5dxg B 458-458 disorder
       Region 5dxg B 459-460 order
       Region 5dxg B 461-472 disorder
       Region 5dxg B 473-548 order
       Region 5dxg B 549-554 disorder
 Evidence X-RAY 5dxg A Reference
       Region 5dxg A 297-306 disorder
       Region 5dxg A 307-460 order
       Region 5dxg A 461-471 disorder
       Region 5dxg A 472-548 order
       Region 5dxg A 549-554 disorder
 Evidence X-RAY 5dxe B Reference
       Region 5dxe B 297-307 disorder
       Region 5dxe B 308-331 order
       Region 5dxe B 332-336 disorder
       Region 5dxe B 337-460 order
       Region 5dxe B 461-471 disorder
       Region 5dxe B 472-548 order
       Region 5dxe B 549-554 disorder
 Evidence X-RAY 5dxe A Reference
       Region 5dxe A 297-306 disorder
       Region 5dxe A 307-461 order
       Region 5dxe A 462-471 disorder
       Region 5dxe A 472-547 order
       Region 5dxe A 548-554 disorder
 Evidence X-RAY 5dxb B Reference
       Region 5dxb B 297-306 disorder
       Region 5dxb B 307-331 order
       Region 5dxb B 332-336 disorder
       Region 5dxb B 337-460 order
       Region 5dxb B 461-472 disorder
       Region 5dxb B 473-532 order
       Region 5dxb B 533-533 disorder
       Region 5dxb B 534-548 order
       Region 5dxb B 549-554 disorder
 Evidence X-RAY 5dxb A Reference
       Region 5dxb A 297-306 disorder
       Region 5dxb A 307-461 order
       Region 5dxb A 462-471 disorder
       Region 5dxb A 472-548 order
       Region 5dxb A 549-554 disorder
 Evidence X-RAY 5dx3 B Reference
       Region 5dx3 B 297-307 disorder
       Region 5dx3 B 308-330 order
       Region 5dx3 B 331-336 disorder
       Region 5dx3 B 337-457 order
       Region 5dx3 B 458-458 disorder
       Region 5dx3 B 459-461 order
       Region 5dx3 B 462-471 disorder
       Region 5dx3 B 472-548 order
       Region 5dx3 B 549-554 disorder
 Evidence X-RAY 5dx3 A Reference
       Region 5dx3 A 297-306 disorder
       Region 5dx3 A 307-461 order
       Region 5dx3 A 462-471 disorder
       Region 5dx3 A 472-547 order
       Region 5dx3 A 548-554 disorder
Seq 297-554 Homo dimer :
 Evidence X-RAY 5w9d B Reference
       Region 5w9d B 306-306 disorder
       Region 5w9d B 307-338 order
       Region 5w9d B 339-340 disorder
       Region 5w9d B 341-545 order
       Region 5w9d B 546-554 disorder
 Evidence X-RAY 5w9d A Reference
       Region 5w9d A 306-306 disorder
       Region 5w9d A 307-336 order
       Region 5w9d A 337-338 disorder
       Region 5w9d A 339-550 order
       Region 5w9d A 551-554 disorder
 Evidence X-RAY 2yja B Reference
       Region 2yja B 299-304 disorder
       Region 2yja B 305-549 order
       Region 2yja B 550-551 disorder
 Evidence X-RAY 1yin A Reference
       Region 1yin A 307-528 order
       Region 1yin A 529-532 disorder
       Region 1yin A 533-551 order
       Region 1yin A 552-554 disorder
 Evidence X-RAY 1yim A Reference
       Region 1yim A 307-551 order
       Region 1yim A 552-554 disorder
 Evidence X-RAY 2yat A Reference
       Region 2yat A 301-330 order
       Region 2yat A 331-340 disorder
       Region 2yat A 341-413 order
       Region 2yat A 414-422 disorder
       Region 2yat A 423-461 order
       Region 2yat A 462-463 disorder
       Region 2yat A 464-548 order
       Region 2yat A 549-551 disorder
 Evidence X-RAY 1xqc D Reference
       Region 1xqc D 301-306 disorder
       Region 1xqc D 307-330 order
       Region 1xqc D 331-340 disorder
       Region 1xqc D 341-461 order
       Region 1xqc D 462-463 disorder
       Region 1xqc D 464-525 order
       Region 1xqc D 526-534 disorder
       Region 1xqc D 535-548 order
       Region 1xqc D 549-553 disorder
 Evidence X-RAY 1xqc C Reference
       Region 1xqc C 301-306 disorder
       Region 1xqc C 307-330 order
       Region 1xqc C 331-340 disorder
       Region 1xqc C 341-461 order
       Region 1xqc C 462-463 disorder
       Region 1xqc C 464-528 order
       Region 1xqc C 529-534 disorder
       Region 1xqc C 535-548 order
       Region 1xqc C 549-553 disorder
 Evidence X-RAY 1xqc B Reference
       Region 1xqc B 301-306 disorder
       Region 1xqc B 307-330 order
       Region 1xqc B 331-340 disorder
       Region 1xqc B 341-461 order
       Region 1xqc B 462-463 disorder
       Region 1xqc B 464-525 order
       Region 1xqc B 526-534 disorder
       Region 1xqc B 535-548 order
       Region 1xqc B 549-553 disorder
 Evidence X-RAY 1xqc A Reference
       Region 1xqc A 301-306 disorder
       Region 1xqc A 307-330 order
       Region 1xqc A 331-340 disorder
       Region 1xqc A 341-461 order
       Region 1xqc A 462-463 disorder
       Region 1xqc A 464-528 order
       Region 1xqc A 529-534 disorder
       Region 1xqc A 535-548 order
       Region 1xqc A 549-553 disorder
 Evidence X-RAY 1xpc A Reference
       Region 1xpc A 307-551 order
       Region 1xpc A 552-554 disorder
 Evidence X-RAY 1xp9 A Reference
       Region 1xp9 A 307-551 order
       Region 1xp9 A 552-554 disorder
 Evidence X-RAY 1xp6 A Reference
       Region 1xp6 A 307-551 order
       Region 1xp6 A 552-554 disorder
 Evidence X-RAY 1xp1 A Reference
       Region 1xp1 A 307-551 order
       Region 1xp1 A 552-554 disorder
 Evidence X-RAY 4xi3 D Reference
       Region 4xi3 D 306-333 order
       Region 4xi3 D 334-340 disorder
       Region 4xi3 D 341-458 order
       Region 4xi3 D 459-470 disorder
       Region 4xi3 D 471-543 order
       Region 4xi3 D 544-548 disorder
 Evidence X-RAY 4xi3 B Reference
       Region 4xi3 B 306-306 disorder
       Region 4xi3 B 307-460 order
       Region 4xi3 B 461-464 disorder
       Region 4xi3 B 465-529 order
       Region 4xi3 B 530-531 disorder
       Region 4xi3 B 532-545 order
       Region 4xi3 B 546-548 disorder
 Evidence X-RAY 4xi3 C Reference
       Region 4xi3 C 306-460 order
       Region 4xi3 C 461-464 disorder
       Region 4xi3 C 465-545 order
       Region 4xi3 C 546-548 disorder
 Evidence X-RAY 4xi3 A Reference
       Region 4xi3 A 306-333 order
       Region 4xi3 A 334-340 disorder
       Region 4xi3 A 341-460 order
       Region 4xi3 A 461-463 disorder
       Region 4xi3 A 464-545 order
       Region 4xi3 A 546-548 disorder
 Evidence X-RAY 3uuc D Reference
       Region 3uuc D 302-306 disorder
       Region 3uuc D 307-417 order
       Region 3uuc D 418-419 disorder
       Region 3uuc D 420-459 order
       Region 3uuc D 460-468 disorder
       Region 3uuc D 469-529 order
       Region 3uuc D 530-532 disorder
       Region 3uuc D 533-552 order
 Evidence X-RAY 3uuc C Reference
       Region 3uuc C 302-305 disorder
       Region 3uuc C 306-335 order
       Region 3uuc C 336-337 disorder
       Region 3uuc C 338-462 order
       Region 3uuc C 463-463 disorder
       Region 3uuc C 464-528 order
       Region 3uuc C 529-536 disorder
       Region 3uuc C 537-545 order
       Region 3uuc C 546-552 disorder
 Evidence X-RAY 3uuc B Reference
       Region 3uuc B 302-305 disorder
       Region 3uuc B 306-415 order
       Region 3uuc B 416-418 disorder
       Region 3uuc B 419-458 order
       Region 3uuc B 459-468 disorder
       Region 3uuc B 469-528 order
       Region 3uuc B 529-532 disorder
       Region 3uuc B 533-552 order
 Evidence X-RAY 3uuc A Reference
       Region 3uuc A 302-304 disorder
       Region 3uuc A 305-335 order
       Region 3uuc A 336-338 disorder
       Region 3uuc A 339-415 order
       Region 3uuc A 416-418 disorder
       Region 3uuc A 419-461 order
       Region 3uuc A 462-467 disorder
       Region 3uuc A 468-529 order
       Region 3uuc A 530-536 disorder
       Region 3uuc A 537-544 order
       Region 3uuc A 545-552 disorder
 Evidence X-RAY 1uom A Reference
       Region 1uom A 301-306 disorder
       Region 1uom A 307-525 order
       Region 1uom A 526-534 disorder
       Region 1uom A 535-546 order
       Region 1uom A 547-553 disorder
 Evidence X-RAY 5ufx B Reference
       Region 5ufx B 306-337 order
       Region 5ufx B 338-340 disorder
       Region 5ufx B 341-460 order
       Region 5ufx B 461-468 disorder
       Region 5ufx B 469-547 order
       Region 5ufx B 548-554 disorder
 Evidence X-RAY 5ufx A Reference
       Region 5ufx A 306-308 disorder
       Region 5ufx A 309-333 order
       Region 5ufx A 334-335 disorder
       Region 5ufx A 336-461 order
       Region 5ufx A 462-464 disorder
       Region 5ufx A 465-547 order
       Region 5ufx A 548-554 disorder
 Evidence X-RAY 5ufw B Reference
       Region 5ufw B 306-337 order
       Region 5ufw B 338-340 disorder
       Region 5ufw B 341-460 order
       Region 5ufw B 461-469 disorder
       Region 5ufw B 470-546 order
       Region 5ufw B 547-554 disorder
 Evidence X-RAY 5ufw A Reference
       Region 5ufw A 306-308 disorder
       Region 5ufw A 309-461 order
       Region 5ufw A 462-464 disorder
       Region 5ufw A 465-548 order
       Region 5ufw A 549-554 disorder
 Evidence X-RAY 5u2b F Reference
       Region 5u2b F 298-301 disorder
       Region 5u2b F 302-329 order
       Region 5u2b F 330-340 disorder
       Region 5u2b F 341-457 order
       Region 5u2b F 458-464 disorder
       Region 5u2b F 465-531 order
       Region 5u2b F 532-535 disorder
       Region 5u2b F 536-548 order
       Region 5u2b F 549-554 disorder
 Evidence X-RAY 5u2b E Reference
       Region 5u2b E 298-305 disorder
       Region 5u2b E 306-333 order
       Region 5u2b E 334-337 disorder
       Region 5u2b E 338-461 order
       Region 5u2b E 462-470 disorder
       Region 5u2b E 471-527 order
       Region 5u2b E 528-536 disorder
       Region 5u2b E 537-548 order
       Region 5u2b E 549-554 disorder
 Evidence X-RAY 5u2b D Reference
       Region 5u2b D 298-303 disorder
       Region 5u2b D 304-330 order
       Region 5u2b D 331-339 disorder
       Region 5u2b D 340-459 order
       Region 5u2b D 460-469 disorder
       Region 5u2b D 470-531 order
       Region 5u2b D 532-533 disorder
       Region 5u2b D 534-550 order
       Region 5u2b D 551-554 disorder
 Evidence X-RAY 5u2b C Reference
       Region 5u2b C 298-299 disorder
       Region 5u2b C 300-461 order
       Region 5u2b C 462-464 disorder
       Region 5u2b C 465-530 order
       Region 5u2b C 531-533 disorder
       Region 5u2b C 534-549 order
       Region 5u2b C 550-554 disorder
 Evidence X-RAY 5u2b B Reference
       Region 5u2b B 298-303 disorder
       Region 5u2b B 304-334 order
       Region 5u2b B 335-339 disorder
       Region 5u2b B 340-459 order
       Region 5u2b B 460-471 disorder
       Region 5u2b B 472-548 order
       Region 5u2b B 549-554 disorder
 Evidence X-RAY 5u2b A Reference
       Region 5u2b A 298-298 disorder
       Region 5u2b A 299-333 order
       Region 5u2b A 334-335 disorder
       Region 5u2b A 336-461 order
       Region 5u2b A 462-462 disorder
       Region 5u2b A 463-530 order
       Region 5u2b A 531-535 disorder
       Region 5u2b A 536-548 order
       Region 5u2b A 549-554 disorder
 Evidence X-RAY 5tnb D Reference
       Region 5tnb D 298-304 disorder
       Region 5tnb D 305-335 order
       Region 5tnb D 336-340 disorder
       Region 5tnb D 341-416 order
       Region 5tnb D 417-419 disorder
       Region 5tnb D 420-461 order
       Region 5tnb D 462-462 disorder
       Region 5tnb D 463-527 order
       Region 5tnb D 528-533 disorder
       Region 5tnb D 534-546 order
       Region 5tnb D 547-554 disorder
 Evidence X-RAY 5tnb C Reference
       Region 5tnb C 298-305 disorder
       Region 5tnb C 306-413 order
       Region 5tnb C 414-419 disorder
       Region 5tnb C 420-461 order
       Region 5tnb C 462-463 disorder
       Region 5tnb C 464-528 order
       Region 5tnb C 529-532 disorder
       Region 5tnb C 533-546 order
       Region 5tnb C 547-554 disorder
 Evidence X-RAY 5tnb B Reference
       Region 5tnb B 298-304 disorder
       Region 5tnb B 305-336 order
       Region 5tnb B 337-340 disorder
       Region 5tnb B 341-415 order
       Region 5tnb B 416-419 disorder
       Region 5tnb B 420-457 order
       Region 5tnb B 458-471 disorder
       Region 5tnb B 472-528 order
       Region 5tnb B 529-533 disorder
       Region 5tnb B 534-546 order
       Region 5tnb B 547-554 disorder
 Evidence X-RAY 5tnb A Reference
       Region 5tnb A 298-305 disorder
       Region 5tnb A 306-412 order
       Region 5tnb A 413-420 disorder
       Region 5tnb A 421-462 order
       Region 5tnb A 463-464 disorder
       Region 5tnb A 465-529 order
       Region 5tnb A 530-533 disorder
       Region 5tnb A 534-546 order
       Region 5tnb A 547-554 disorder
 Evidence X-RAY 5tn9 D Reference
       Region 5tn9 D 298-304 disorder
       Region 5tn9 D 305-332 order
       Region 5tn9 D 333-340 disorder
       Region 5tn9 D 341-415 order
       Region 5tn9 D 416-420 disorder
       Region 5tn9 D 421-460 order
       Region 5tn9 D 461-463 disorder
       Region 5tn9 D 464-526 order
       Region 5tn9 D 527-533 disorder
       Region 5tn9 D 534-546 order
       Region 5tn9 D 547-554 disorder
 Evidence X-RAY 5tn9 C Reference
       Region 5tn9 C 298-306 disorder
       Region 5tn9 C 307-413 order
       Region 5tn9 C 414-420 disorder
       Region 5tn9 C 421-461 order
       Region 5tn9 C 462-465 disorder
       Region 5tn9 C 466-527 order
       Region 5tn9 C 528-532 disorder
       Region 5tn9 C 533-546 order
       Region 5tn9 C 547-554 disorder
 Evidence X-RAY 5tn9 B Reference
       Region 5tn9 B 298-304 disorder
       Region 5tn9 B 305-330 order
       Region 5tn9 B 331-340 disorder
       Region 5tn9 B 341-415 order
       Region 5tn9 B 416-420 disorder
       Region 5tn9 B 421-458 order
       Region 5tn9 B 459-469 disorder
       Region 5tn9 B 470-527 order
       Region 5tn9 B 528-532 disorder
       Region 5tn9 B 533-546 order
       Region 5tn9 B 547-554 disorder
 Evidence X-RAY 5tn9 A Reference
       Region 5tn9 A 298-305 disorder
       Region 5tn9 A 306-413 order
       Region 5tn9 A 414-420 disorder
       Region 5tn9 A 421-461 order
       Region 5tn9 A 462-467 disorder
       Region 5tn9 A 468-524 order
       Region 5tn9 A 525-530 disorder
       Region 5tn9 A 531-546 order
       Region 5tn9 A 547-554 disorder
 Evidence X-RAY 5t97 B Reference
       Region 5t97 B 301-308 disorder
       Region 5t97 B 309-329 order
       Region 5t97 B 330-342 disorder
       Region 5t97 B 343-412 order
       Region 5t97 B 413-419 disorder
       Region 5t97 B 420-457 order
       Region 5t97 B 458-464 disorder
       Region 5t97 B 465-526 order
       Region 5t97 B 527-553 disorder
 Evidence X-RAY 5t97 A Reference
       Region 5t97 A 301-309 disorder
       Region 5t97 A 310-328 order
       Region 5t97 A 329-342 disorder
       Region 5t97 A 343-410 order
       Region 5t97 A 411-419 disorder
       Region 5t97 A 420-457 order
       Region 5t97 A 458-473 disorder
       Region 5t97 A 474-525 order
       Region 5t97 A 526-553 disorder
 Evidence X-RAY 5t92 B Reference
       Region 5t92 B 301-306 disorder
       Region 5t92 B 307-329 order
       Region 5t92 B 330-342 disorder
       Region 5t92 B 343-412 order
       Region 5t92 B 413-420 disorder
       Region 5t92 B 421-456 order
       Region 5t92 B 457-472 disorder
       Region 5t92 B 473-526 order
       Region 5t92 B 527-553 disorder
 Evidence X-RAY 5t92 A Reference
       Region 5t92 A 301-309 disorder
       Region 5t92 A 310-329 order
       Region 5t92 A 330-337 disorder
       Region 5t92 A 338-410 order
       Region 5t92 A 411-419 disorder
       Region 5t92 A 420-457 order
       Region 5t92 A 458-473 disorder
       Region 5t92 A 474-525 order
       Region 5t92 A 526-553 disorder
 Evidence X-RAY 1sj0 A Reference
       Region 1sj0 A 307-530 order
       Region 1sj0 A 531-532 disorder
       Region 1sj0 A 533-551 order
       Region 1sj0 A 552-554 disorder
 Evidence X-RAY 2r6y B Reference
       Region 2r6y B 304-305 disorder
       Region 2r6y B 306-329 order
       Region 2r6y B 330-340 disorder
       Region 2r6y B 341-461 order
       Region 2r6y B 462-463 disorder
       Region 2r6y B 464-528 order
       Region 2r6y B 529-534 disorder
       Region 2r6y B 535-545 order
       Region 2r6y B 546-551 disorder
 Evidence X-RAY 2r6y A Reference
       Region 2r6y A 304-305 disorder
       Region 2r6y A 306-333 order
       Region 2r6y A 334-340 disorder
       Region 2r6y A 341-528 order
       Region 2r6y A 529-533 disorder
       Region 2r6y A 534-549 order
       Region 2r6y A 550-551 disorder
 Evidence X-RAY 2r6w B Reference
       Region 2r6w B 304-305 disorder
       Region 2r6w B 306-331 order
       Region 2r6w B 332-339 disorder
       Region 2r6w B 340-461 order
       Region 2r6w B 462-463 disorder
       Region 2r6w B 464-526 order
       Region 2r6w B 527-534 disorder
       Region 2r6w B 535-546 order
       Region 2r6w B 547-551 disorder
 Evidence X-RAY 2r6w A Reference
       Region 2r6w A 304-305 disorder
       Region 2r6w A 306-331 order
       Region 2r6w A 332-339 disorder
       Region 2r6w A 340-526 order
       Region 2r6w A 527-533 disorder
       Region 2r6w A 534-549 order
       Region 2r6w A 550-551 disorder
 Evidence X-RAY 1r5k C Reference
       Region 1r5k C 297-305 disorder
       Region 1r5k C 306-332 order
       Region 1r5k C 333-336 disorder
       Region 1r5k C 337-544 order
       Region 1r5k C 545-554 disorder
 Evidence X-RAY 1r5k B Reference
       Region 1r5k B 297-305 disorder
       Region 1r5k B 306-332 order
       Region 1r5k B 333-336 disorder
       Region 1r5k B 337-544 order
       Region 1r5k B 545-554 disorder
 Evidence X-RAY 1r5k A Reference
       Region 1r5k A 297-305 disorder
       Region 1r5k A 306-332 order
       Region 1r5k A 333-336 disorder
       Region 1r5k A 337-545 order
       Region 1r5k A 546-554 disorder
 Evidence X-RAY 2qxs B Reference
       Region 2qxs B 298-305 disorder
       Region 2qxs B 306-331 order
       Region 2qxs B 332-339 disorder
       Region 2qxs B 340-459 order
       Region 2qxs B 460-468 disorder
       Region 2qxs B 469-548 order
       Region 2qxs B 549-554 disorder
 Evidence X-RAY 2qxs A Reference
       Region 2qxs A 298-305 disorder
       Region 2qxs A 306-333 order
       Region 2qxs A 334-334 disorder
       Region 2qxs A 335-338 order
       Region 2qxs A 339-339 disorder
       Region 2qxs A 340-461 order
       Region 2qxs A 462-464 disorder
       Region 2qxs A 465-547 order
       Region 2qxs A 548-554 disorder
 Evidence X-RAY 2qe4 B Reference
       Region 2qe4 B 304-305 disorder
       Region 2qe4 B 306-330 order
       Region 2qe4 B 331-340 disorder
       Region 2qe4 B 341-461 order
       Region 2qe4 B 462-470 disorder
       Region 2qe4 B 471-528 order
       Region 2qe4 B 529-551 disorder
 Evidence X-RAY 2qe4 A Reference
       Region 2qe4 A 304-305 disorder
       Region 2qe4 A 306-330 order
       Region 2qe4 A 331-335 disorder
       Region 2qe4 A 336-460 order
       Region 2qe4 A 461-471 disorder
       Region 2qe4 A 472-528 order
       Region 2qe4 A 529-551 disorder
 Evidence X-RAY 2q70 B Reference
       Region 2q70 B 304-305 disorder
       Region 2q70 B 306-330 order
       Region 2q70 B 331-340 disorder
       Region 2q70 B 341-461 order
       Region 2q70 B 462-463 disorder
       Region 2q70 B 464-528 order
       Region 2q70 B 529-551 disorder
 Evidence X-RAY 2q70 A Reference
       Region 2q70 A 304-305 disorder
       Region 2q70 A 306-333 order
       Region 2q70 A 334-337 disorder
       Region 2q70 A 338-528 order
       Region 2q70 A 529-533 disorder
       Region 2q70 A 534-549 order
       Region 2q70 A 550-551 disorder
 Evidence X-RAY 4q50 H Reference
       Region 4q50 H 299-306 disorder
       Region 4q50 H 307-331 order
       Region 4q50 H 332-339 disorder
       Region 4q50 H 340-461 order
       Region 4q50 H 462-467 disorder
       Region 4q50 H 468-526 order
       Region 4q50 H 527-534 disorder
       Region 4q50 H 535-546 order
       Region 4q50 H 547-554 disorder
 Evidence X-RAY 4q50 D Reference
       Region 4q50 D 299-305 disorder
       Region 4q50 D 306-330 order
       Region 4q50 D 331-339 disorder
       Region 4q50 D 340-458 order
       Region 4q50 D 459-466 disorder
       Region 4q50 D 467-528 order
       Region 4q50 D 529-535 disorder
       Region 4q50 D 536-545 order
       Region 4q50 D 546-554 disorder
 Evidence X-RAY 4q50 G Reference
       Region 4q50 G 299-306 disorder
       Region 4q50 G 307-331 order
       Region 4q50 G 332-339 disorder
       Region 4q50 G 340-460 order
       Region 4q50 G 461-467 disorder
       Region 4q50 G 468-528 order
       Region 4q50 G 529-534 disorder
       Region 4q50 G 535-546 order
       Region 4q50 G 547-554 disorder
 Evidence X-RAY 4q50 C Reference
       Region 4q50 C 299-305 disorder
       Region 4q50 C 306-330 order
       Region 4q50 C 331-340 disorder
       Region 4q50 C 341-418 order
       Region 4q50 C 419-420 disorder
       Region 4q50 C 421-460 order
       Region 4q50 C 461-462 disorder
       Region 4q50 C 463-465 order
       Region 4q50 C 466-467 disorder
       Region 4q50 C 468-527 order
       Region 4q50 C 528-532 disorder
       Region 4q50 C 533-546 order
       Region 4q50 C 547-554 disorder
 Evidence X-RAY 4q50 E Reference
       Region 4q50 E 299-305 disorder
       Region 4q50 E 306-331 order
       Region 4q50 E 332-339 disorder
       Region 4q50 E 340-418 order
       Region 4q50 E 419-419 disorder
       Region 4q50 E 420-461 order
       Region 4q50 E 462-467 disorder
       Region 4q50 E 468-528 order
       Region 4q50 E 529-535 disorder
       Region 4q50 E 536-545 order
       Region 4q50 E 546-554 disorder
 Evidence X-RAY 4q50 B Reference
       Region 4q50 B 299-306 disorder
       Region 4q50 B 307-330 order
       Region 4q50 B 331-341 disorder
       Region 4q50 B 342-417 order
       Region 4q50 B 418-419 disorder
       Region 4q50 B 420-458 order
       Region 4q50 B 459-468 disorder
       Region 4q50 B 469-528 order
       Region 4q50 B 529-535 disorder
       Region 4q50 B 536-545 order
       Region 4q50 B 546-554 disorder
 Evidence X-RAY 4q50 F Reference
       Region 4q50 F 299-306 disorder
       Region 4q50 F 307-331 order
       Region 4q50 F 332-335 disorder
       Region 4q50 F 336-458 order
       Region 4q50 F 459-459 disorder
       Region 4q50 F 460-461 order
       Region 4q50 F 462-467 disorder
       Region 4q50 F 468-527 order
       Region 4q50 F 528-535 disorder
       Region 4q50 F 536-545 order
       Region 4q50 F 546-554 disorder
 Evidence X-RAY 4q50 A Reference
       Region 4q50 A 299-306 disorder
       Region 4q50 A 307-329 order
       Region 4q50 A 330-341 disorder
       Region 4q50 A 342-399 order
       Region 4q50 A 400-400 disorder
       Region 4q50 A 401-416 order
       Region 4q50 A 417-419 disorder
       Region 4q50 A 420-459 order
       Region 4q50 A 460-467 disorder
       Region 4q50 A 468-527 order
       Region 4q50 A 528-532 disorder
       Region 4q50 A 533-545 order
       Region 4q50 A 546-554 disorder
 Evidence X-RAY 2pog B Reference
       Region 2pog B 304-305 disorder
       Region 2pog B 306-330 order
       Region 2pog B 331-340 disorder
       Region 2pog B 341-461 order
       Region 2pog B 462-463 disorder
       Region 2pog B 464-528 order
       Region 2pog B 529-551 disorder
 Evidence X-RAY 2pog A Reference
       Region 2pog A 304-305 disorder
       Region 2pog A 306-331 order
       Region 2pog A 332-339 disorder
       Region 2pog A 340-529 order
       Region 2pog A 530-533 disorder
       Region 2pog A 534-550 order
       Region 2pog A 551-551 disorder
 Evidence X-RAY 2ouz A Reference
       Region 2ouz A 301-305 disorder
       Region 2ouz A 306-551 order
       Region 2ouz A 552-553 disorder
 Evidence X-RAY 2iok B Reference
       Region 2iok B 301-305 disorder
       Region 2iok B 306-335 order
       Region 2iok B 336-339 disorder
       Region 2iok B 340-527 order
       Region 2iok B 528-534 disorder
       Region 2iok B 535-544 order
       Region 2iok B 545-554 disorder
 Evidence X-RAY 2iok A Reference
       Region 2iok A 301-305 disorder
       Region 2iok A 306-331 order
       Region 2iok A 332-338 disorder
       Region 2iok A 339-529 order
       Region 2iok A 530-534 disorder
       Region 2iok A 535-544 order
       Region 2iok A 545-554 disorder
 Evidence X-RAY 2iog A Reference
       Region 2iog A 309-551 order
       Region 2iog A 552-554 disorder
 Evidence X-RAY 2i0j D Reference
       Region 2i0j D 304-305 disorder
       Region 2i0j D 306-332 order
       Region 2i0j D 333-340 disorder
       Region 2i0j D 341-461 order
       Region 2i0j D 462-463 disorder
       Region 2i0j D 464-528 order
       Region 2i0j D 529-535 disorder
       Region 2i0j D 536-547 order
 Evidence X-RAY 2i0j C Reference
       Region 2i0j C 304-305 disorder
       Region 2i0j C 306-528 order
       Region 2i0j C 529-547 disorder
 Evidence X-RAY 2i0j B Reference
       Region 2i0j B 304-305 disorder
       Region 2i0j B 306-332 order
       Region 2i0j B 333-339 disorder
       Region 2i0j B 340-461 order
       Region 2i0j B 462-463 disorder
       Region 2i0j B 464-528 order
       Region 2i0j B 529-534 disorder
       Region 2i0j B 535-547 order
 Evidence X-RAY 2i0j A Reference
       Region 2i0j A 304-305 disorder
       Region 2i0j A 306-461 order
       Region 2i0j A 462-463 disorder
       Region 2i0j A 464-528 order
       Region 2i0j A 529-547 disorder
 Evidence X-RAY 1g50 C Reference
       Region 1g50 C 304-547 order
       Region 1g50 C 548-550 disorder
 Evidence X-RAY 1g50 B Reference
       Region 1g50 B 304-549 order
       Region 1g50 B 550-550 disorder
 Evidence X-RAY 1g50 A Reference
       Region 1g50 A 304-550 order
 Evidence X-RAY 3ert A Reference
       Region 3ert A 297-305 disorder
       Region 3ert A 306-551 order
       Region 3ert A 552-554 disorder
 Evidence X-RAY 1err B Reference
       Region 1err B 301-305 disorder
       Region 1err B 306-331 order
       Region 1err B 332-339 disorder
       Region 1err B 340-459 order
       Region 1err B 460-468 disorder
       Region 1err B 469-529 order
       Region 1err B 530-535 disorder
       Region 1err B 536-551 order
       Region 1err B 552-553 disorder
 Evidence X-RAY 1err A Reference
       Region 1err A 301-306 disorder
       Region 1err A 307-459 order
       Region 1err A 460-469 disorder
       Region 1err A 470-528 order
       Region 1err A 529-534 disorder
       Region 1err A 535-547 order
       Region 1err A 548-553 disorder
 Evidence X-RAY 1ere F Reference
       Region 1ere F 301-304 disorder
       Region 1ere F 305-330 order
       Region 1ere F 331-336 disorder
       Region 1ere F 337-461 order
       Region 1ere F 462-464 disorder
       Region 1ere F 465-548 order
       Region 1ere F 549-553 disorder
 Evidence X-RAY 1ere E Reference
       Region 1ere E 301-304 disorder
       Region 1ere E 305-330 order
       Region 1ere E 331-336 disorder
       Region 1ere E 337-461 order
       Region 1ere E 462-464 disorder
       Region 1ere E 465-548 order
       Region 1ere E 549-553 disorder
 Evidence X-RAY 1ere D Reference
       Region 1ere D 301-304 disorder
       Region 1ere D 305-330 order
       Region 1ere D 331-336 disorder
       Region 1ere D 337-461 order
       Region 1ere D 462-464 disorder
       Region 1ere D 465-548 order
       Region 1ere D 549-553 disorder
 Evidence X-RAY 1ere C Reference
       Region 1ere C 301-304 disorder
       Region 1ere C 305-330 order
       Region 1ere C 331-336 disorder
       Region 1ere C 337-461 order
       Region 1ere C 462-464 disorder
       Region 1ere C 465-548 order
       Region 1ere C 549-553 disorder
 Evidence X-RAY 1ere B Reference
       Region 1ere B 301-304 disorder
       Region 1ere B 305-330 order
       Region 1ere B 331-336 disorder
       Region 1ere B 337-461 order
       Region 1ere B 462-464 disorder
       Region 1ere B 465-548 order
       Region 1ere B 549-553 disorder
 Evidence X-RAY 1ere A Reference
       Region 1ere A 301-304 disorder
       Region 1ere A 305-330 order
       Region 1ere A 331-336 disorder
       Region 1ere A 337-461 order
       Region 1ere A 462-464 disorder
       Region 1ere A 465-548 order
       Region 1ere A 549-553 disorder
 Evidence X-RAY 3dt3 B Reference
       Region 3dt3 B 299-305 disorder
       Region 3dt3 B 306-461 order
       Region 3dt3 B 462-463 disorder
       Region 3dt3 B 464-530 order
       Region 3dt3 B 531-531 disorder
       Region 3dt3 B 532-548 order
       Region 3dt3 B 549-551 disorder
 Evidence X-RAY 3dt3 A Reference
       Region 3dt3 A 299-305 disorder
       Region 3dt3 A 306-330 order
       Region 3dt3 A 331-337 disorder
       Region 3dt3 A 338-461 order
       Region 3dt3 A 462-462 disorder
       Region 3dt3 A 463-529 order
       Region 3dt3 A 530-531 disorder
       Region 3dt3 A 532-551 order
 Evidence X-RAY 6c42 B Reference
       Region 6c42 B 307-333 order
       Region 6c42 B 334-335 disorder
       Region 6c42 B 336-337 order
       Region 6c42 B 338-340 disorder
       Region 6c42 B 341-416 order
       Region 6c42 B 417-418 disorder
       Region 6c42 B 419-459 order
       Region 6c42 B 460-469 disorder
       Region 6c42 B 470-547 order
       Region 6c42 B 548-554 disorder
 Evidence X-RAY 6c42 A Reference
       Region 6c42 A 307-310 disorder
       Region 6c42 A 311-333 order
       Region 6c42 A 334-335 disorder
       Region 6c42 A 336-461 order
       Region 6c42 A 462-463 disorder
       Region 6c42 A 464-548 order
       Region 6c42 A 549-554 disorder
 Evidence X-RAY 5ak2 B Reference
       Region 5ak2 B 307-307 disorder
       Region 5ak2 B 308-330 order
       Region 5ak2 B 331-335 disorder
       Region 5ak2 B 336-459 order
       Region 5ak2 B 460-471 disorder
       Region 5ak2 B 472-528 order
       Region 5ak2 B 529-539 disorder
       Region 5ak2 B 540-545 order
       Region 5ak2 B 546-554 disorder
 Evidence X-RAY 5ak2 A Reference
       Region 5ak2 A 307-330 order
       Region 5ak2 A 331-340 disorder
       Region 5ak2 A 341-460 order
       Region 5ak2 A 461-467 disorder
       Region 5ak2 A 468-528 order
       Region 5ak2 A 529-533 disorder
       Region 5ak2 A 534-552 order
       Region 5ak2 A 553-554 disorder
 Evidence X-RAY 5aav B Reference
       Region 5aav B 306-330 order
       Region 5aav B 331-334 disorder
       Region 5aav B 335-417 order
       Region 5aav B 418-420 disorder
       Region 5aav B 421-457 order
       Region 5aav B 458-471 disorder
       Region 5aav B 472-526 order
       Region 5aav B 527-536 disorder
       Region 5aav B 537-545 order
       Region 5aav B 546-554 disorder
 Evidence X-RAY 5aav A Reference
       Region 5aav A 307-415 order
       Region 5aav A 416-420 disorder
       Region 5aav A 421-461 order
       Region 5aav A 462-469 disorder
       Region 5aav A 470-528 order
       Region 5aav A 529-532 disorder
       Region 5aav A 533-551 order
       Region 5aav A 552-554 disorder
 Evidence X-RAY 5aau B Reference
       Region 5aau B 307-309 disorder
       Region 5aau B 310-331 order
       Region 5aau B 332-335 disorder
       Region 5aau B 336-463 order
       Region 5aau B 464-470 disorder
       Region 5aau B 471-528 order
       Region 5aau B 529-532 disorder
       Region 5aau B 533-546 order
       Region 5aau B 547-554 disorder
 Evidence X-RAY 5aau A Reference
       Region 5aau A 307-331 order
       Region 5aau A 332-340 disorder
       Region 5aau A 341-461 order
       Region 5aau A 462-469 disorder
       Region 5aau A 470-528 order
       Region 5aau A 529-532 disorder
       Region 5aau A 533-552 order
       Region 5aau A 553-554 disorder
 Evidence X-RAY 1a52 B Reference
       Region 1a52 B 297-304 disorder
       Region 1a52 B 305-544 order
       Region 1a52 B 545-554 disorder
 Evidence X-RAY 1a52 A Reference
       Region 1a52 A 297-305 disorder
       Region 1a52 A 306-544 order
       Region 1a52 A 545-554 disorder
Seq 297-554 Hetero tetramer : Q61026
 Evidence X-RAY 2qzo B Reference
       Region 2qzo B 298-305 disorder
       Region 2qzo B 306-461 order
       Region 2qzo B 462-468 disorder
       Region 2qzo B 469-549 order
       Region 2qzo B 550-554 disorder
 Evidence X-RAY 2qzo A Reference
       Region 2qzo A 298-304 disorder
       Region 2qzo A 305-412 order
       Region 2qzo A 413-419 disorder
       Region 2qzo A 420-458 order
       Region 2qzo A 459-468 disorder
       Region 2qzo A 469-549 order
       Region 2qzo A 550-554 disorder
 Evidence X-RAY 2qxm B Reference
       Region 2qxm B 298-305 disorder
       Region 2qxm B 306-461 order
       Region 2qxm B 462-464 disorder
       Region 2qxm B 465-550 order
       Region 2qxm B 551-554 disorder
 Evidence X-RAY 2qxm A Reference
       Region 2qxm A 298-304 disorder
       Region 2qxm A 305-331 order
       Region 2qxm A 332-334 disorder
       Region 2qxm A 335-413 order
       Region 2qxm A 414-418 disorder
       Region 2qxm A 419-461 order
       Region 2qxm A 462-465 disorder
       Region 2qxm A 466-549 order
       Region 2qxm A 550-554 disorder
 Evidence X-RAY 2qse B Reference
       Region 2qse B 298-305 disorder
       Region 2qse B 306-461 order
       Region 2qse B 462-464 disorder
       Region 2qse B 465-550 order
       Region 2qse B 551-554 disorder
 Evidence X-RAY 2qse A Reference
       Region 2qse A 298-304 disorder
       Region 2qse A 305-330 order
       Region 2qse A 331-334 disorder
       Region 2qse A 335-413 order
       Region 2qse A 414-416 disorder
       Region 2qse A 417-549 order
       Region 2qse A 550-554 disorder
 Evidence X-RAY 2qr9 B Reference
       Region 2qr9 B 298-305 disorder
       Region 2qr9 B 306-461 order
       Region 2qr9 B 462-464 disorder
       Region 2qr9 B 465-550 order
       Region 2qr9 B 551-554 disorder
 Evidence X-RAY 2qr9 A Reference
       Region 2qr9 A 298-304 disorder
       Region 2qr9 A 305-331 order
       Region 2qr9 A 332-334 disorder
       Region 2qr9 A 335-549 order
       Region 2qr9 A 550-554 disorder
 Evidence X-RAY 2qh6 B Reference
       Region 2qh6 B 298-304 disorder
       Region 2qh6 B 305-332 order
       Region 2qh6 B 333-336 disorder
       Region 2qh6 B 337-461 order
       Region 2qh6 B 462-472 disorder
       Region 2qh6 B 473-547 order
       Region 2qh6 B 548-554 disorder
 Evidence X-RAY 2qh6 A Reference
       Region 2qh6 A 298-303 disorder
       Region 2qh6 A 304-332 order
       Region 2qh6 A 333-334 disorder
       Region 2qh6 A 335-461 order
       Region 2qh6 A 462-471 disorder
       Region 2qh6 A 472-532 order
       Region 2qh6 A 533-533 disorder
       Region 2qh6 A 534-548 order
       Region 2qh6 A 549-554 disorder
 Evidence X-RAY 2qgw B Reference
       Region 2qgw B 298-304 disorder
       Region 2qgw B 305-460 order
       Region 2qgw B 461-463 disorder
       Region 2qgw B 464-549 order
       Region 2qgw B 550-554 disorder
 Evidence X-RAY 2qgw A Reference
       Region 2qgw A 298-304 disorder
       Region 2qgw A 305-461 order
       Region 2qgw A 462-469 disorder
       Region 2qgw A 470-548 order
       Region 2qgw A 549-554 disorder
 Evidence X-RAY 2qgt B Reference
       Region 2qgt B 298-304 disorder
       Region 2qgt B 305-461 order
       Region 2qgt B 462-466 disorder
       Region 2qgt B 467-548 order
       Region 2qgt B 549-554 disorder
 Evidence X-RAY 2qgt A Reference
       Region 2qgt A 298-304 disorder
       Region 2qgt A 305-461 order
       Region 2qgt A 462-468 disorder
       Region 2qgt A 469-548 order
       Region 2qgt A 549-554 disorder
 Evidence X-RAY 2qab B Reference
       Region 2qab B 298-304 disorder
       Region 2qab B 305-549 order
       Region 2qab B 550-554 disorder
 Evidence X-RAY 2qab A Reference
       Region 2qab A 298-304 disorder
       Region 2qab A 305-461 order
       Region 2qab A 462-469 disorder
       Region 2qab A 470-548 order
       Region 2qab A 549-554 disorder
 Evidence X-RAY 2qa8 B Reference
       Region 2qa8 B 298-304 disorder
       Region 2qa8 B 305-459 order
       Region 2qa8 B 460-469 disorder
       Region 2qa8 B 470-549 order
       Region 2qa8 B 550-554 disorder
 Evidence X-RAY 2qa8 A Reference
       Region 2qa8 A 298-304 disorder
       Region 2qa8 A 305-330 order
       Region 2qa8 A 331-336 disorder
       Region 2qa8 A 337-461 order
       Region 2qa8 A 462-469 disorder
       Region 2qa8 A 470-548 order
       Region 2qa8 A 549-554 disorder
 Evidence X-RAY 2qa6 B Reference
       Region 2qa6 B 298-305 disorder
       Region 2qa6 B 306-461 order
       Region 2qa6 B 462-464 disorder
       Region 2qa6 B 465-550 order
       Region 2qa6 B 551-554 disorder
 Evidence X-RAY 2qa6 A Reference
       Region 2qa6 A 298-304 disorder
       Region 2qa6 A 305-332 order
       Region 2qa6 A 333-334 disorder
       Region 2qa6 A 335-549 order
       Region 2qa6 A 550-554 disorder
 Evidence X-RAY 2q6j B Reference
       Region 2q6j B 298-304 disorder
       Region 2q6j B 305-458 order
       Region 2q6j B 459-469 disorder
       Region 2q6j B 470-548 order
       Region 2q6j B 549-554 disorder
 Evidence X-RAY 2q6j A Reference
       Region 2q6j A 298-305 disorder
       Region 2q6j A 306-460 order
       Region 2q6j A 461-462 disorder
       Region 2q6j A 463-549 order
       Region 2q6j A 550-554 disorder
 Evidence X-RAY 1l2i B Reference
       Region 1l2i B 297-304 disorder
       Region 1l2i B 305-460 order
       Region 1l2i B 461-471 disorder
       Region 1l2i B 472-547 order
       Region 1l2i B 548-554 disorder
 Evidence X-RAY 1l2i A Reference
       Region 1l2i A 297-304 disorder
       Region 1l2i A 305-459 order
       Region 1l2i A 460-468 disorder
       Region 1l2i A 469-547 order
       Region 1l2i A 548-554 disorder
Seq 297-559 Hetero tetramer : IID00082Complex
 Evidence X-RAY 4znw B Reference
       Region 4znw B 301-304 disorder
       Region 4znw B 305-459 order
       Region 4znw B 460-471 disorder
       Region 4znw B 472-529 order
       Region 4znw B 530-533 disorder
       Region 4znw B 534-548 order
       Region 4znw B 549-559 disorder
 Evidence X-RAY 4znw A Reference
       Region 4znw A 301-305 disorder
       Region 4znw A 306-459 order
       Region 4znw A 460-471 disorder
       Region 4znw A 472-551 order
       Region 4znw A 552-559 disorder
 Evidence X-RAY 4znv B Reference
       Region 4znv B 301-304 disorder
       Region 4znv B 305-461 order
       Region 4znv B 462-466 disorder
       Region 4znv B 467-552 order
       Region 4znv B 553-559 disorder
 Evidence X-RAY 4znv A Reference
       Region 4znv A 301-303 disorder
       Region 4znv A 304-331 order
       Region 4znv A 332-332 disorder
       Region 4znv A 333-460 order
       Region 4znv A 461-471 disorder
       Region 4znv A 472-552 order
       Region 4znv A 553-559 disorder
 Evidence X-RAY 4znu B Reference
       Region 4znu B 301-305 disorder
       Region 4znu B 306-331 order
       Region 4znu B 332-335 disorder
       Region 4znu B 336-460 order
       Region 4znu B 461-472 disorder
       Region 4znu B 473-528 order
       Region 4znu B 529-532 disorder
       Region 4znu B 533-551 order
       Region 4znu B 552-559 disorder
 Evidence X-RAY 4znu A Reference
       Region 4znu A 301-305 disorder
       Region 4znu A 306-460 order
       Region 4znu A 461-464 disorder
       Region 4znu A 465-528 order
       Region 4znu A 529-532 disorder
       Region 4znu A 533-548 order
       Region 4znu A 549-559 disorder
 Evidence X-RAY 4znt B Reference
       Region 4znt B 301-304 disorder
       Region 4znt B 305-461 order
       Region 4znt B 462-464 disorder
       Region 4znt B 465-527 order
       Region 4znt B 528-535 disorder
       Region 4znt B 536-548 order
       Region 4znt B 549-559 disorder
 Evidence X-RAY 4znt A Reference
       Region 4znt A 301-304 disorder
       Region 4znt A 305-331 order
       Region 4znt A 332-335 disorder
       Region 4znt A 336-461 order
       Region 4znt A 462-471 disorder
       Region 4znt A 472-530 order
       Region 4znt A 531-531 disorder
       Region 4znt A 532-548 order
       Region 4znt A 549-559 disorder
 Evidence X-RAY 4zns B Reference
       Region 4zns B 301-305 disorder
       Region 4zns B 306-461 order
       Region 4zns B 462-466 disorder
       Region 4zns B 467-529 order
       Region 4zns B 530-532 disorder
       Region 4zns B 533-549 order
       Region 4zns B 550-559 disorder
 Evidence X-RAY 4zns A Reference
       Region 4zns A 301-305 disorder
       Region 4zns A 306-331 order
       Region 4zns A 332-335 disorder
       Region 4zns A 336-462 order
       Region 4zns A 463-471 disorder
       Region 4zns A 472-529 order
       Region 4zns A 530-531 disorder
       Region 4zns A 532-551 order
       Region 4zns A 552-559 disorder
 Evidence X-RAY 4znh B Reference
       Region 4znh B 301-304 disorder
       Region 4znh B 305-332 order
       Region 4znh B 333-336 disorder
       Region 4znh B 337-458 order
       Region 4znh B 459-469 disorder
       Region 4znh B 470-529 order
       Region 4znh B 530-531 disorder
       Region 4znh B 532-548 order
       Region 4znh B 549-559 disorder
 Evidence X-RAY 4znh A Reference
       Region 4znh A 301-305 disorder
       Region 4znh A 306-461 order
       Region 4znh A 462-468 disorder
       Region 4znh A 469-551 order
       Region 4znh A 552-559 disorder
 Evidence X-RAY 4zn9 B Reference
       Region 4zn9 B 301-304 disorder
       Region 4zn9 B 305-457 order
       Region 4zn9 B 458-472 disorder
       Region 4zn9 B 473-554 order
       Region 4zn9 B 555-559 disorder
 Evidence X-RAY 4zn9 A Reference
       Region 4zn9 A 301-304 disorder
       Region 4zn9 A 305-459 order
       Region 4zn9 A 460-472 disorder
       Region 4zn9 A 473-554 order
       Region 4zn9 A 555-559 disorder
 Evidence X-RAY 4zn7 B Reference
       Region 4zn7 B 301-304 disorder
       Region 4zn7 B 305-461 order
       Region 4zn7 B 462-469 disorder
       Region 4zn7 B 470-548 order
       Region 4zn7 B 549-559 disorder
 Evidence X-RAY 4zn7 A Reference
       Region 4zn7 A 301-304 disorder
       Region 4zn7 A 305-461 order
       Region 4zn7 A 462-471 disorder
       Region 4zn7 A 472-548 order
       Region 4zn7 A 549-559 disorder
 Evidence X-RAY 1zky B Reference
       Region 1zky B 298-304 disorder
       Region 1zky B 305-549 order
       Region 1zky B 550-554 disorder
 Evidence X-RAY 1zky A Reference
       Region 1zky A 298-303 disorder
       Region 1zky A 304-461 order
       Region 1zky A 462-468 disorder
       Region 1zky A 469-549 order
       Region 1zky A 550-554 disorder
 Evidence X-RAY 5u2d B Reference
       Region 5u2d B 298-302 disorder
       Region 5u2d B 303-459 order
       Region 5u2d B 460-471 disorder
       Region 5u2d B 472-553 order
       Region 5u2d B 554-554 disorder
 Evidence X-RAY 5u2d A Reference
       Region 5u2d A 298-304 disorder
       Region 5u2d A 305-461 order
       Region 5u2d A 462-464 disorder
       Region 5u2d A 465-553 order
       Region 5u2d A 554-554 disorder
 Evidence X-RAY 5tn8 B Reference
       Region 5tn8 B 298-307 disorder
       Region 5tn8 B 308-461 order
       Region 5tn8 B 462-467 disorder
       Region 5tn8 B 468-548 order
       Region 5tn8 B 549-554 disorder
 Evidence X-RAY 5tn8 A Reference
       Region 5tn8 A 298-304 disorder
       Region 5tn8 A 305-330 order
       Region 5tn8 A 331-335 disorder
       Region 5tn8 A 336-460 order
       Region 5tn8 A 461-471 disorder
       Region 5tn8 A 472-548 order
       Region 5tn8 A 549-554 disorder
 Evidence X-RAY 5tn7 B Reference
       Region 5tn7 B 298-304 disorder
       Region 5tn7 B 305-461 order
       Region 5tn7 B 462-469 disorder
       Region 5tn7 B 470-547 order
       Region 5tn7 B 548-554 disorder
 Evidence X-RAY 5tn7 A Reference
       Region 5tn7 A 298-304 disorder
       Region 5tn7 A 305-461 order
       Region 5tn7 A 462-469 disorder
       Region 5tn7 A 470-548 order
       Region 5tn7 A 549-554 disorder
 Evidence X-RAY 5tn6 B Reference
       Region 5tn6 B 298-304 disorder
       Region 5tn6 B 305-331 order
       Region 5tn6 B 332-335 disorder
       Region 5tn6 B 336-460 order
       Region 5tn6 B 461-470 disorder
       Region 5tn6 B 471-548 order
       Region 5tn6 B 549-554 disorder
 Evidence X-RAY 5tn6 A Reference
       Region 5tn6 A 298-304 disorder
       Region 5tn6 A 305-461 order
       Region 5tn6 A 462-469 disorder
       Region 5tn6 A 470-548 order
       Region 5tn6 A 549-554 disorder
 Evidence X-RAY 5tn5 B Reference
       Region 5tn5 B 298-304 disorder
       Region 5tn5 B 305-460 order
       Region 5tn5 B 461-469 disorder
       Region 5tn5 B 470-548 order
       Region 5tn5 B 549-554 disorder
 Evidence X-RAY 5tn5 A Reference
       Region 5tn5 A 298-303 disorder
       Region 5tn5 A 304-461 order
       Region 5tn5 A 462-471 disorder
       Region 5tn5 A 472-548 order
       Region 5tn5 A 549-554 disorder
 Evidence X-RAY 5tn4 B Reference
       Region 5tn4 B 298-304 disorder
       Region 5tn4 B 305-461 order
       Region 5tn4 B 462-463 disorder
       Region 5tn4 B 464-549 order
       Region 5tn4 B 550-554 disorder
 Evidence X-RAY 5tn4 A Reference
       Region 5tn4 A 298-304 disorder
       Region 5tn4 A 305-461 order
       Region 5tn4 A 462-471 disorder
       Region 5tn4 A 472-548 order
       Region 5tn4 A 549-554 disorder
 Evidence X-RAY 5tn3 B Reference
       Region 5tn3 B 298-303 disorder
       Region 5tn3 B 304-461 order
       Region 5tn3 B 462-464 disorder
       Region 5tn3 B 465-549 order
       Region 5tn3 B 550-554 disorder
 Evidence X-RAY 5tn3 A Reference
       Region 5tn3 A 298-302 disorder
       Region 5tn3 A 303-461 order
       Region 5tn3 A 462-469 disorder
       Region 5tn3 A 470-548 order
       Region 5tn3 A 549-554 disorder
 Evidence X-RAY 5tn1 B Reference
       Region 5tn1 B 298-303 disorder
       Region 5tn1 B 304-461 order
       Region 5tn1 B 462-463 disorder
       Region 5tn1 B 464-550 order
       Region 5tn1 B 551-554 disorder
 Evidence X-RAY 5tn1 A Reference
       Region 5tn1 A 298-300 disorder
       Region 5tn1 A 301-331 order
       Region 5tn1 A 332-334 disorder
       Region 5tn1 A 335-548 order
       Region 5tn1 A 549-554 disorder
 Evidence X-RAY 5tmz B Reference
       Region 5tmz B 298-303 disorder
       Region 5tmz B 304-461 order
       Region 5tmz B 462-463 disorder
       Region 5tmz B 464-548 order
       Region 5tmz B 549-554 disorder
 Evidence X-RAY 5tmz A Reference
       Region 5tmz A 298-303 disorder
       Region 5tmz A 304-461 order
       Region 5tmz A 462-470 disorder
       Region 5tmz A 471-548 order
       Region 5tmz A 549-554 disorder
 Evidence X-RAY 5tmw B Reference
       Region 5tmw B 298-304 disorder
       Region 5tmw B 305-333 order
       Region 5tmw B 334-336 disorder
       Region 5tmw B 337-462 order
       Region 5tmw B 463-464 disorder
       Region 5tmw B 465-549 order
       Region 5tmw B 550-554 disorder
 Evidence X-RAY 5tmw A Reference
       Region 5tmw A 298-301 disorder
       Region 5tmw A 302-461 order
       Region 5tmw A 462-468 disorder
       Region 5tmw A 469-548 order
       Region 5tmw A 549-554 disorder
 Evidence X-RAY 5tmv B Reference
       Region 5tmv B 298-303 disorder
       Region 5tmv B 304-461 order
       Region 5tmv B 462-464 disorder
       Region 5tmv B 465-530 order
       Region 5tmv B 531-533 disorder
       Region 5tmv B 534-548 order
       Region 5tmv B 549-554 disorder
 Evidence X-RAY 5tmv A Reference
       Region 5tmv A 298-303 disorder
       Region 5tmv A 304-460 order
       Region 5tmv A 461-469 disorder
       Region 5tmv A 470-548 order
       Region 5tmv A 549-554 disorder
 Evidence X-RAY 5tmu B Reference
       Region 5tmu B 298-303 disorder
       Region 5tmu B 304-461 order
       Region 5tmu B 462-471 disorder
       Region 5tmu B 472-548 order
       Region 5tmu B 549-554 disorder
 Evidence X-RAY 5tmu A Reference
       Region 5tmu A 298-304 disorder
       Region 5tmu A 305-461 order
       Region 5tmu A 462-464 disorder
       Region 5tmu A 465-548 order
       Region 5tmu A 549-554 disorder
 Evidence X-RAY 5tmt B Reference
       Region 5tmt B 298-303 disorder
       Region 5tmt B 304-460 order
       Region 5tmt B 461-471 disorder
       Region 5tmt B 472-548 order
       Region 5tmt B 549-554 disorder
 Evidence X-RAY 5tmt A Reference
       Region 5tmt A 298-304 disorder
       Region 5tmt A 305-417 order
       Region 5tmt A 418-420 disorder
       Region 5tmt A 421-460 order
       Region 5tmt A 461-464 disorder
       Region 5tmt A 465-548 order
       Region 5tmt A 549-554 disorder
 Evidence X-RAY 5tms B Reference
       Region 5tms B 298-301 disorder
       Region 5tms B 302-460 order
       Region 5tms B 461-464 disorder
       Region 5tms B 465-548 order
       Region 5tms B 549-554 disorder
 Evidence X-RAY 5tms A Reference
       Region 5tms A 298-304 disorder
       Region 5tms A 305-461 order
       Region 5tms A 462-471 disorder
       Region 5tms A 472-548 order
       Region 5tms A 549-554 disorder
 Evidence X-RAY 5tmr B Reference
       Region 5tmr B 298-303 disorder
       Region 5tmr B 304-461 order
       Region 5tmr B 462-469 disorder
       Region 5tmr B 470-548 order
       Region 5tmr B 549-554 disorder
 Evidence X-RAY 5tmr A Reference
       Region 5tmr A 298-303 disorder
       Region 5tmr A 304-461 order
       Region 5tmr A 462-464 disorder
       Region 5tmr A 465-548 order
       Region 5tmr A 549-554 disorder
 Evidence X-RAY 5tmq B Reference
       Region 5tmq B 298-302 disorder
       Region 5tmq B 303-461 order
       Region 5tmq B 462-464 disorder
       Region 5tmq B 465-548 order
       Region 5tmq B 549-554 disorder
 Evidence X-RAY 5tmq A Reference
       Region 5tmq A 298-304 disorder
       Region 5tmq A 305-461 order
       Region 5tmq A 462-471 disorder
       Region 5tmq A 472-548 order
       Region 5tmq A 549-554 disorder
 Evidence X-RAY 5tmo B Reference
       Region 5tmo B 298-304 disorder
       Region 5tmo B 305-461 order
       Region 5tmo B 462-466 disorder
       Region 5tmo B 467-548 order
       Region 5tmo B 549-554 disorder
 Evidence X-RAY 5tmo A Reference
       Region 5tmo A 298-303 disorder
       Region 5tmo A 304-461 order
       Region 5tmo A 462-471 disorder
       Region 5tmo A 472-548 order
       Region 5tmo A 549-554 disorder
 Evidence X-RAY 5tmm B Reference
       Region 5tmm B 298-304 disorder
       Region 5tmm B 305-331 order
       Region 5tmm B 332-335 disorder
       Region 5tmm B 336-460 order
       Region 5tmm B 461-471 disorder
       Region 5tmm B 472-529 order
       Region 5tmm B 530-536 disorder
       Region 5tmm B 537-548 order
       Region 5tmm B 549-554 disorder
 Evidence X-RAY 5tmm A Reference
       Region 5tmm A 298-305 disorder
       Region 5tmm A 306-332 order
       Region 5tmm A 333-336 disorder
       Region 5tmm A 337-415 order
       Region 5tmm A 416-417 disorder
       Region 5tmm A 418-461 order
       Region 5tmm A 462-471 disorder
       Region 5tmm A 472-531 order
       Region 5tmm A 532-535 disorder
       Region 5tmm A 536-548 order
       Region 5tmm A 549-554 disorder
 Evidence X-RAY 5tml B Reference
       Region 5tml B 298-304 disorder
       Region 5tml B 305-532 order
       Region 5tml B 533-535 disorder
       Region 5tml B 536-548 order
       Region 5tml B 549-554 disorder
 Evidence X-RAY 5tml A Reference
       Region 5tml A 298-302 disorder
       Region 5tml A 303-461 order
       Region 5tml A 462-471 disorder
       Region 5tml A 472-531 order
       Region 5tml A 532-535 disorder
       Region 5tml A 536-551 order
       Region 5tml A 552-554 disorder
 Evidence X-RAY 5tm9 B Reference
       Region 5tm9 B 298-304 disorder
       Region 5tm9 B 305-332 order
       Region 5tm9 B 333-335 disorder
       Region 5tm9 B 336-460 order
       Region 5tm9 B 461-471 disorder
       Region 5tm9 B 472-529 order
       Region 5tm9 B 530-554 disorder
 Evidence X-RAY 5tm9 A Reference
       Region 5tm9 A 298-304 disorder
       Region 5tm9 A 305-461 order
       Region 5tm9 A 462-469 disorder
       Region 5tm9 A 470-527 order
       Region 5tm9 A 528-554 disorder
 Evidence X-RAY 5tm8 B Reference
       Region 5tm8 B 298-303 disorder
       Region 5tm8 B 304-331 order
       Region 5tm8 B 332-335 disorder
       Region 5tm8 B 336-461 order
       Region 5tm8 B 462-471 disorder
       Region 5tm8 B 472-529 order
       Region 5tm8 B 530-532 disorder
       Region 5tm8 B 533-548 order
       Region 5tm8 B 549-554 disorder
 Evidence X-RAY 5tm8 A Reference
       Region 5tm8 A 298-304 disorder
       Region 5tm8 A 305-461 order
       Region 5tm8 A 462-466 disorder
       Region 5tm8 A 467-530 order
       Region 5tm8 A 531-534 disorder
       Region 5tm8 A 535-548 order
       Region 5tm8 A 549-554 disorder
 Evidence X-RAY 5tm7 B Reference
       Region 5tm7 B 298-304 disorder
       Region 5tm7 B 305-531 order
       Region 5tm7 B 532-535 disorder
       Region 5tm7 B 536-548 order
       Region 5tm7 B 549-554 disorder
 Evidence X-RAY 5tm7 A Reference
       Region 5tm7 A 298-303 disorder
       Region 5tm7 A 304-463 order
       Region 5tm7 A 464-471 disorder
       Region 5tm7 A 472-529 order
       Region 5tm7 A 530-534 disorder
       Region 5tm7 A 535-550 order
       Region 5tm7 A 551-554 disorder
 Evidence X-RAY 5tm6 B Reference
       Region 5tm6 B 298-303 disorder
       Region 5tm6 B 304-461 order
       Region 5tm6 B 462-463 disorder
       Region 5tm6 B 464-548 order
       Region 5tm6 B 549-554 disorder
 Evidence X-RAY 5tm6 A Reference
       Region 5tm6 A 298-303 disorder
       Region 5tm6 A 304-333 order
       Region 5tm6 A 334-335 disorder
       Region 5tm6 A 336-462 order
       Region 5tm6 A 463-471 disorder
       Region 5tm6 A 472-548 order
       Region 5tm6 A 549-554 disorder
 Evidence X-RAY 5tm5 B Reference
       Region 5tm5 B 298-303 disorder
       Region 5tm5 B 304-418 order
       Region 5tm5 B 419-420 disorder
       Region 5tm5 B 421-461 order
       Region 5tm5 B 462-471 disorder
       Region 5tm5 B 472-548 order
       Region 5tm5 B 549-554 disorder
 Evidence X-RAY 5tm5 A Reference
       Region 5tm5 A 298-304 disorder
       Region 5tm5 A 305-461 order
       Region 5tm5 A 462-466 disorder
       Region 5tm5 A 467-548 order
       Region 5tm5 A 549-554 disorder
 Evidence X-RAY 5tm4 B Reference
       Region 5tm4 B 298-304 disorder
       Region 5tm4 B 305-331 order
       Region 5tm4 B 332-337 disorder
       Region 5tm4 B 338-460 order
       Region 5tm4 B 461-472 disorder
       Region 5tm4 B 473-528 order
       Region 5tm4 B 529-536 disorder
       Region 5tm4 B 537-548 order
       Region 5tm4 B 549-554 disorder
 Evidence X-RAY 5tm4 A Reference
       Region 5tm4 A 298-304 disorder
       Region 5tm4 A 305-461 order
       Region 5tm4 A 462-469 disorder
       Region 5tm4 A 470-528 order
       Region 5tm4 A 529-536 disorder
       Region 5tm4 A 537-548 order
       Region 5tm4 A 549-554 disorder
 Evidence X-RAY 5tm3 B Reference
       Region 5tm3 B 298-302 disorder
       Region 5tm3 B 303-461 order
       Region 5tm3 B 462-464 disorder
       Region 5tm3 B 465-548 order
       Region 5tm3 B 549-554 disorder
 Evidence X-RAY 5tm3 A Reference
       Region 5tm3 A 298-304 disorder
       Region 5tm3 A 305-332 order
       Region 5tm3 A 333-335 disorder
       Region 5tm3 A 336-461 order
       Region 5tm3 A 462-471 disorder
       Region 5tm3 A 472-548 order
       Region 5tm3 A 549-554 disorder
 Evidence X-RAY 5tm2 B Reference
       Region 5tm2 B 298-306 disorder
       Region 5tm2 B 307-336 order
       Region 5tm2 B 337-337 disorder
       Region 5tm2 B 338-461 order
       Region 5tm2 B 462-467 disorder
       Region 5tm2 B 468-533 order
       Region 5tm2 B 534-535 disorder
       Region 5tm2 B 536-546 order
       Region 5tm2 B 547-554 disorder
 Evidence X-RAY 5tm2 A Reference
       Region 5tm2 A 298-305 disorder
       Region 5tm2 A 306-330 order
       Region 5tm2 A 331-336 disorder
       Region 5tm2 A 337-417 order
       Region 5tm2 A 418-420 disorder
       Region 5tm2 A 421-460 order
       Region 5tm2 A 461-471 disorder
       Region 5tm2 A 472-530 order
       Region 5tm2 A 531-534 disorder
       Region 5tm2 A 535-546 order
       Region 5tm2 A 547-554 disorder
 Evidence X-RAY 5tm1 B Reference
       Region 5tm1 B 298-307 disorder
       Region 5tm1 B 308-336 order
       Region 5tm1 B 337-337 disorder
       Region 5tm1 B 338-460 order
       Region 5tm1 B 461-469 disorder
       Region 5tm1 B 470-532 order
       Region 5tm1 B 533-535 disorder
       Region 5tm1 B 536-546 order
       Region 5tm1 B 547-554 disorder
 Evidence X-RAY 5tm1 A Reference
       Region 5tm1 A 298-305 disorder
       Region 5tm1 A 306-330 order
       Region 5tm1 A 331-336 disorder
       Region 5tm1 A 337-460 order
       Region 5tm1 A 461-472 disorder
       Region 5tm1 A 473-530 order
       Region 5tm1 A 531-535 disorder
       Region 5tm1 A 536-548 order
       Region 5tm1 A 549-554 disorder
 Evidence X-RAY 5tly B Reference
       Region 5tly B 298-304 disorder
       Region 5tly B 305-461 order
       Region 5tly B 462-466 disorder
       Region 5tly B 467-532 order
       Region 5tly B 533-535 disorder
       Region 5tly B 536-548 order
       Region 5tly B 549-554 disorder
 Evidence X-RAY 5tly A Reference
       Region 5tly A 298-304 disorder
       Region 5tly A 305-330 order
       Region 5tly A 331-333 disorder
       Region 5tly A 334-460 order
       Region 5tly A 461-469 disorder
       Region 5tly A 470-549 order
       Region 5tly A 550-554 disorder
 Evidence X-RAY 5tlx B Reference
       Region 5tlx B 298-304 disorder
       Region 5tlx B 305-461 order
       Region 5tlx B 462-463 disorder
       Region 5tlx B 464-548 order
       Region 5tlx B 549-554 disorder
 Evidence X-RAY 5tlx A Reference
       Region 5tlx A 298-304 disorder
       Region 5tlx A 305-461 order
       Region 5tlx A 462-471 disorder
       Region 5tlx A 472-548 order
       Region 5tlx A 549-554 disorder
 Evidence X-RAY 5tlv B Reference
       Region 5tlv B 298-304 disorder
       Region 5tlv B 305-461 order
       Region 5tlv B 462-463 disorder
       Region 5tlv B 464-548 order
       Region 5tlv B 549-554 disorder
 Evidence X-RAY 5tlv A Reference
       Region 5tlv A 298-303 disorder
       Region 5tlv A 304-463 order
       Region 5tlv A 464-469 disorder
       Region 5tlv A 470-548 order
       Region 5tlv A 549-554 disorder
 Evidence X-RAY 5tlu B Reference
       Region 5tlu B 298-304 disorder
       Region 5tlu B 305-460 order
       Region 5tlu B 461-467 disorder
       Region 5tlu B 468-549 order
       Region 5tlu B 550-554 disorder
 Evidence X-RAY 5tlu A Reference
       Region 5tlu A 298-304 disorder
       Region 5tlu A 305-331 order
       Region 5tlu A 332-335 disorder
       Region 5tlu A 336-460 order
       Region 5tlu A 461-471 disorder
       Region 5tlu A 472-548 order
       Region 5tlu A 549-554 disorder
 Evidence X-RAY 5tlt B Reference
       Region 5tlt B 298-304 disorder
       Region 5tlt B 305-460 order
       Region 5tlt B 461-465 disorder
       Region 5tlt B 466-549 order
       Region 5tlt B 550-554 disorder
 Evidence X-RAY 5tlt A Reference
       Region 5tlt A 298-302 disorder
       Region 5tlt A 303-459 order
       Region 5tlt A 460-471 disorder
       Region 5tlt A 472-548 order
       Region 5tlt A 549-554 disorder
 Evidence X-RAY 5tlp B Reference
       Region 5tlp B 298-304 disorder
       Region 5tlp B 305-331 order
       Region 5tlp B 332-337 disorder
       Region 5tlp B 338-458 order
       Region 5tlp B 459-469 disorder
       Region 5tlp B 470-528 order
       Region 5tlp B 529-554 disorder
 Evidence X-RAY 5tlp A Reference
       Region 5tlp A 298-304 disorder
       Region 5tlp A 305-333 order
       Region 5tlp A 334-335 disorder
       Region 5tlp A 336-461 order
       Region 5tlp A 462-469 disorder
       Region 5tlp A 470-548 order
       Region 5tlp A 549-554 disorder
 Evidence X-RAY 5tlo B Reference
       Region 5tlo B 298-304 disorder
       Region 5tlo B 305-334 order
       Region 5tlo B 335-335 disorder
       Region 5tlo B 336-460 order
       Region 5tlo B 461-471 disorder
       Region 5tlo B 472-548 order
       Region 5tlo B 549-554 disorder
 Evidence X-RAY 5tlo A Reference
       Region 5tlo A 298-305 disorder
       Region 5tlo A 306-332 order
       Region 5tlo A 333-334 disorder
       Region 5tlo A 335-413 order
       Region 5tlo A 414-418 disorder
       Region 5tlo A 419-461 order
       Region 5tlo A 462-466 disorder
       Region 5tlo A 467-529 order
       Region 5tlo A 530-531 disorder
       Region 5tlo A 532-548 order
       Region 5tlo A 549-554 disorder
 Evidence X-RAY 5tlm B Reference
       Region 5tlm B 298-305 disorder
       Region 5tlm B 306-333 order
       Region 5tlm B 334-336 disorder
       Region 5tlm B 337-459 order
       Region 5tlm B 460-472 disorder
       Region 5tlm B 473-548 order
       Region 5tlm B 549-554 disorder
 Evidence X-RAY 5tlm A Reference
       Region 5tlm A 298-305 disorder
       Region 5tlm A 306-417 order
       Region 5tlm A 418-418 disorder
       Region 5tlm A 419-460 order
       Region 5tlm A 461-470 disorder
       Region 5tlm A 471-529 order
       Region 5tlm A 530-535 disorder
       Region 5tlm A 536-548 order
       Region 5tlm A 549-554 disorder
 Evidence X-RAY 5tll B Reference
       Region 5tll B 298-304 disorder
       Region 5tll B 305-331 order
       Region 5tll B 332-332 disorder
       Region 5tll B 333-460 order
       Region 5tll B 461-469 disorder
       Region 5tll B 470-548 order
       Region 5tll B 549-554 disorder
 Evidence X-RAY 5tll A Reference
       Region 5tll A 298-304 disorder
       Region 5tll A 305-460 order
       Region 5tll A 461-469 disorder
       Region 5tll A 470-548 order
       Region 5tll A 549-554 disorder
 Evidence X-RAY 5tlg B Reference
       Region 5tlg B 298-304 disorder
       Region 5tlg B 305-461 order
       Region 5tlg B 462-469 disorder
       Region 5tlg B 470-548 order
       Region 5tlg B 549-554 disorder
 Evidence X-RAY 5tlg A Reference
       Region 5tlg A 298-304 disorder
       Region 5tlg A 305-331 order
       Region 5tlg A 332-336 disorder
       Region 5tlg A 337-461 order
       Region 5tlg A 462-471 disorder
       Region 5tlg A 472-548 order
       Region 5tlg A 549-554 disorder
 Evidence X-RAY 5tlf B Reference
       Region 5tlf B 298-304 disorder
       Region 5tlf B 305-414 order
       Region 5tlf B 415-417 disorder
       Region 5tlf B 418-461 order
       Region 5tlf B 462-465 disorder
       Region 5tlf B 466-532 order
       Region 5tlf B 533-534 disorder
       Region 5tlf B 535-548 order
       Region 5tlf B 549-554 disorder
 Evidence X-RAY 5tlf A Reference
       Region 5tlf A 298-303 disorder
       Region 5tlf A 304-461 order
       Region 5tlf A 462-469 disorder
       Region 5tlf A 470-548 order
       Region 5tlf A 549-554 disorder
 Evidence X-RAY 5tld B Reference
       Region 5tld B 298-304 disorder
       Region 5tld B 305-336 order
       Region 5tld B 337-337 disorder
       Region 5tld B 338-460 order
       Region 5tld B 461-467 disorder
       Region 5tld B 468-531 order
       Region 5tld B 532-532 disorder
       Region 5tld B 533-548 order
       Region 5tld B 549-554 disorder
 Evidence X-RAY 5tld A Reference
       Region 5tld A 298-304 disorder
       Region 5tld A 305-331 order
       Region 5tld A 332-334 disorder
       Region 5tld A 335-460 order
       Region 5tld A 461-471 disorder
       Region 5tld A 472-548 order
       Region 5tld A 549-554 disorder
 Evidence X-RAY 5t1z B Reference
       Region 5t1z B 305-331 order
       Region 5t1z B 332-333 disorder
       Region 5t1z B 334-461 order
       Region 5t1z B 462-465 disorder
       Region 5t1z B 466-548 order
       Region 5t1z B 549-554 disorder
 Evidence X-RAY 5t1z A Reference
       Region 5t1z A 305-461 order
       Region 5t1z A 462-466 disorder
       Region 5t1z A 467-549 order
       Region 5t1z A 550-554 disorder
 Evidence X-RAY 4pxm B Reference
       Region 4pxm B 299-304 disorder
       Region 4pxm B 305-330 order
       Region 4pxm B 331-337 disorder
       Region 4pxm B 338-460 order
       Region 4pxm B 461-471 disorder
       Region 4pxm B 472-548 order
       Region 4pxm B 549-554 disorder
 Evidence X-RAY 4pxm A Reference
       Region 4pxm A 299-306 disorder
       Region 4pxm A 307-459 order
       Region 4pxm A 460-472 disorder
       Region 4pxm A 473-549 order
       Region 4pxm A 550-554 disorder
 Evidence X-RAY 4pps B Reference
       Region 4pps B 305-461 order
       Region 4pps B 462-469 disorder
       Region 4pps B 470-548 order
 Evidence X-RAY 4pps A Reference
       Region 4pps A 305-358 order
       Region 4pps A 359-359 disorder
       Region 4pps A 360-461 order
       Region 4pps A 462-466 disorder
       Region 4pps A 467-548 order
 Evidence X-RAY 4ppp B Reference
       Region 4ppp B 305-308 disorder
       Region 4ppp B 309-461 order
       Region 4ppp B 462-466 disorder
       Region 4ppp B 467-548 order
 Evidence X-RAY 4ppp A Reference
       Region 4ppp A 305-330 order
       Region 4ppp A 331-336 disorder
       Region 4ppp A 337-461 order
       Region 4ppp A 462-471 disorder
       Region 4ppp A 472-548 order
 Evidence X-RAY 4pp6 B Reference
       Region 4pp6 B 305-332 order
       Region 4pp6 B 333-336 disorder
       Region 4pp6 B 337-460 order
       Region 4pp6 B 461-470 disorder
       Region 4pp6 B 471-548 order
 Evidence X-RAY 4pp6 A Reference
       Region 4pp6 A 305-461 order
       Region 4pp6 A 462-471 disorder
       Region 4pp6 A 472-548 order
 Evidence X-RAY 2p15 B Reference
       Region 2p15 B 298-305 disorder
       Region 2p15 B 306-461 order
       Region 2p15 B 462-464 disorder
       Region 2p15 B 465-550 order
       Region 2p15 B 551-554 disorder
 Evidence X-RAY 2p15 A Reference
       Region 2p15 A 298-304 disorder
       Region 2p15 A 305-331 order
       Region 2p15 A 332-334 disorder
       Region 2p15 A 335-549 order
       Region 2p15 A 550-554 disorder
 Evidence X-RAY 5kro B Reference
       Region 5kro B 298-305 disorder
       Region 5kro B 306-336 order
       Region 5kro B 337-337 disorder
       Region 5kro B 338-414 order
       Region 5kro B 415-417 disorder
       Region 5kro B 418-460 order
       Region 5kro B 461-469 disorder
       Region 5kro B 470-533 order
       Region 5kro B 534-534 disorder
       Region 5kro B 535-547 order
       Region 5kro B 548-554 disorder
 Evidence X-RAY 5kro A Reference
       Region 5kro A 298-305 disorder
       Region 5kro A 306-331 order
       Region 5kro A 332-334 disorder
       Region 5kro A 335-460 order
       Region 5kro A 461-471 disorder
       Region 5kro A 472-548 order
       Region 5kro A 549-554 disorder
 Evidence X-RAY 5krm B Reference
       Region 5krm B 298-304 disorder
       Region 5krm B 305-333 order
       Region 5krm B 334-334 disorder
       Region 5krm B 335-461 order
       Region 5krm B 462-465 disorder
       Region 5krm B 466-549 order
       Region 5krm B 550-554 disorder
 Evidence X-RAY 5krm A Reference
       Region 5krm A 298-304 disorder
       Region 5krm A 305-461 order
       Region 5krm A 462-469 disorder
       Region 5krm A 470-549 order
       Region 5krm A 550-554 disorder
 Evidence X-RAY 5krl B Reference
       Region 5krl B 298-304 disorder
       Region 5krl B 305-330 order
       Region 5krl B 331-335 disorder
       Region 5krl B 336-460 order
       Region 5krl B 461-470 disorder
       Region 5krl B 471-532 order
       Region 5krl B 533-533 disorder
       Region 5krl B 534-548 order
       Region 5krl B 549-554 disorder
 Evidence X-RAY 5krl A Reference
       Region 5krl A 298-304 disorder
       Region 5krl A 305-461 order
       Region 5krl A 462-469 disorder
       Region 5krl A 470-548 order
       Region 5krl A 549-554 disorder
 Evidence X-RAY 5krk B Reference
       Region 5krk B 298-305 disorder
       Region 5krk B 306-330 order
       Region 5krk B 331-333 disorder
       Region 5krk B 334-414 order
       Region 5krk B 415-418 disorder
       Region 5krk B 419-460 order
       Region 5krk B 461-468 disorder
       Region 5krk B 469-529 order
       Region 5krk B 530-535 disorder
       Region 5krk B 536-547 order
       Region 5krk B 548-554 disorder
 Evidence X-RAY 5krk A Reference
       Region 5krk A 298-304 disorder
       Region 5krk A 305-331 order
       Region 5krk A 332-335 disorder
       Region 5krk A 336-460 order
       Region 5krk A 461-471 disorder
       Region 5krk A 472-532 order
       Region 5krk A 533-533 disorder
       Region 5krk A 534-548 order
       Region 5krk A 549-554 disorder
 Evidence X-RAY 5krj B Reference
       Region 5krj B 298-305 disorder
       Region 5krj B 306-461 order
       Region 5krj B 462-469 disorder
       Region 5krj B 470-528 order
       Region 5krj B 529-534 disorder
       Region 5krj B 535-548 order
       Region 5krj B 549-554 disorder
 Evidence X-RAY 5krj A Reference
       Region 5krj A 298-303 disorder
       Region 5krj A 304-332 order
       Region 5krj A 333-335 disorder
       Region 5krj A 336-460 order
       Region 5krj A 461-471 disorder
       Region 5krj A 472-548 order
       Region 5krj A 549-554 disorder
 Evidence X-RAY 5kri B Reference
       Region 5kri B 298-305 disorder
       Region 5kri B 306-334 order
       Region 5kri B 335-335 disorder
       Region 5kri B 336-461 order
       Region 5kri B 462-468 disorder
       Region 5kri B 469-533 order
       Region 5kri B 534-535 disorder
       Region 5kri B 536-548 order
       Region 5kri B 549-554 disorder
 Evidence X-RAY 5kri A Reference
       Region 5kri A 298-304 disorder
       Region 5kri A 305-331 order
       Region 5kri A 332-333 disorder
       Region 5kri A 334-461 order
       Region 5kri A 462-469 disorder
       Region 5kri A 470-548 order
       Region 5kri A 549-554 disorder
 Evidence X-RAY 5krh B Reference
       Region 5krh B 298-304 disorder
       Region 5krh B 305-414 order
       Region 5krh B 415-416 disorder
       Region 5krh B 417-461 order
       Region 5krh B 462-466 disorder
       Region 5krh B 467-548 order
       Region 5krh B 549-554 disorder
 Evidence X-RAY 5krh A Reference
       Region 5krh A 298-304 disorder
       Region 5krh A 305-332 order
       Region 5krh A 333-334 disorder
       Region 5krh A 335-461 order
       Region 5krh A 462-472 disorder
       Region 5krh A 473-548 order
       Region 5krh A 549-554 disorder
 Evidence X-RAY 5krf B Reference
       Region 5krf B 298-304 disorder
       Region 5krf B 305-416 order
       Region 5krf B 417-420 disorder
       Region 5krf B 421-460 order
       Region 5krf B 461-465 disorder
       Region 5krf B 466-549 order
       Region 5krf B 550-554 disorder
 Evidence X-RAY 5krf A Reference
       Region 5krf A 298-303 disorder
       Region 5krf A 304-460 order
       Region 5krf A 461-471 disorder
       Region 5krf A 472-548 order
       Region 5krf A 549-554 disorder
 Evidence X-RAY 5krc B Reference
       Region 5krc B 298-304 disorder
       Region 5krc B 305-461 order
       Region 5krc B 462-469 disorder
       Region 5krc B 470-550 order
       Region 5krc B 551-554 disorder
 Evidence X-RAY 5krc A Reference
       Region 5krc A 298-303 disorder
       Region 5krc A 304-332 order
       Region 5krc A 333-334 disorder
       Region 5krc A 335-461 order
       Region 5krc A 462-471 disorder
       Region 5krc A 472-548 order
       Region 5krc A 549-554 disorder
 Evidence X-RAY 5kra F Reference
       Region 5kra F 298-304 disorder
       Region 5kra F 305-417 order
       Region 5kra F 418-419 disorder
       Region 5kra F 420-460 order
       Region 5kra F 461-466 disorder
       Region 5kra F 467-549 order
       Region 5kra F 550-554 disorder
 Evidence X-RAY 5kra E Reference
       Region 5kra E 298-304 disorder
       Region 5kra E 305-331 order
       Region 5kra E 332-336 disorder
       Region 5kra E 337-461 order
       Region 5kra E 462-471 disorder
       Region 5kra E 472-533 order
       Region 5kra E 534-534 disorder
       Region 5kra E 535-548 order
       Region 5kra E 549-554 disorder
 Evidence X-RAY 5kra B Reference
       Region 5kra B 298-304 disorder
       Region 5kra B 305-414 order
       Region 5kra B 415-417 disorder
       Region 5kra B 418-461 order
       Region 5kra B 462-463 disorder
       Region 5kra B 464-549 order
       Region 5kra B 550-554 disorder
 Evidence X-RAY 5kra A Reference
       Region 5kra A 298-304 disorder
       Region 5kra A 305-331 order
       Region 5kra A 332-336 disorder
       Region 5kra A 337-414 order
       Region 5kra A 415-417 disorder
       Region 5kra A 418-461 order
       Region 5kra A 462-471 disorder
       Region 5kra A 472-548 order
       Region 5kra A 549-554 disorder
 Evidence X-RAY 5kr9 B Reference
       Region 5kr9 B 298-304 disorder
       Region 5kr9 B 305-459 order
       Region 5kr9 B 460-470 disorder
       Region 5kr9 B 471-548 order
       Region 5kr9 B 549-554 disorder
 Evidence X-RAY 5kr9 A Reference
       Region 5kr9 A 298-303 disorder
       Region 5kr9 A 304-461 order
       Region 5kr9 A 462-471 disorder
       Region 5kr9 A 472-549 order
       Region 5kr9 A 550-554 disorder
 Evidence X-RAY 5kce B Reference
       Region 5kce B 298-304 disorder
       Region 5kce B 303-304 disorder
       Region 5kce B 305-529 order
       Region 5kce B 530-534 disorder
       Region 5kce B 535-548 order
       Region 5kce B 549-554 disorder
       Region 5kce B 549-549 disorder
 Evidence X-RAY 5kce A Reference
       Region 5kce A 298-302 disorder
       Region 5kce A 303-331 order
       Region 5kce A 332-340 disorder
       Region 5kce A 341-457 order
       Region 5kce A 458-472 disorder
       Region 5kce A 473-549 order
       Region 5kce A 550-554 disorder
 Evidence X-RAY 5hyr B Reference
       Region 5hyr B 302-306 disorder
       Region 5hyr B 307-331 order
       Region 5hyr B 332-337 disorder
       Region 5hyr B 338-460 order
       Region 5hyr B 461-472 disorder
       Region 5hyr B 473-547 order
       Region 5hyr B 548-559 disorder
 Evidence X-RAY 5hyr A Reference
       Region 5hyr A 302-306 disorder
       Region 5hyr A 307-461 order
       Region 5hyr A 462-472 disorder
       Region 5hyr A 473-547 order
       Region 5hyr A 548-548 disorder
       Region 5hyr A 549-549 order
       Region 5hyr A 550-559 disorder
 Evidence X-RAY 2g5o B Reference
       Region 2g5o B 298-303 disorder
       Region 2g5o B 304-462 order
       Region 2g5o B 463-470 disorder
       Region 2g5o B 471-550 order
       Region 2g5o B 551-554 disorder
 Evidence X-RAY 2g5o A Reference
       Region 2g5o A 298-303 disorder
       Region 2g5o A 304-461 order
       Region 2g5o A 462-468 disorder
       Region 2g5o A 469-548 order
       Region 2g5o A 549-554 disorder
 Evidence X-RAY 2g44 B Reference
       Region 2g44 B 298-305 disorder
       Region 2g44 B 306-461 order
       Region 2g44 B 462-471 disorder
       Region 2g44 B 472-552 order
       Region 2g44 B 553-554 disorder
 Evidence X-RAY 2g44 A Reference
       Region 2g44 A 298-304 disorder
       Region 2g44 A 305-461 order
       Region 2g44 A 462-468 disorder
       Region 2g44 A 469-548 order
       Region 2g44 A 549-554 disorder
 Evidence X-RAY 2fai B Reference
       Region 2fai B 298-303 disorder
       Region 2fai B 304-548 order
       Region 2fai B 549-554 disorder
 Evidence X-RAY 2fai A Reference
       Region 2fai A 298-304 disorder
       Region 2fai A 305-461 order
       Region 2fai A 462-469 disorder
       Region 2fai A 470-548 order
       Region 2fai A 549-554 disorder
 Evidence X-RAY 3erd B Reference
       Region 3erd B 297-304 disorder
       Region 3erd B 305-461 order
       Region 3erd B 462-469 disorder
       Region 3erd B 470-549 order
       Region 3erd B 550-554 disorder
 Evidence X-RAY 3erd A Reference
       Region 3erd A 297-304 disorder
       Region 3erd A 305-549 order
       Region 3erd A 550-554 disorder
 Evidence X-RAY 5eit B Reference
       Region 5eit B 298-305 disorder
       Region 5eit B 306-460 order
       Region 5eit B 461-470 disorder
       Region 5eit B 471-550 order
       Region 5eit B 551-554 disorder
 Evidence X-RAY 5eit A Reference
       Region 5eit A 298-304 disorder
       Region 5eit A 305-460 order
       Region 5eit A 461-471 disorder
       Region 5eit A 472-549 order
       Region 5eit A 550-554 disorder
 Evidence X-RAY 5ei1 B Reference
       Region 5ei1 B 298-305 disorder
       Region 5ei1 B 306-335 order
       Region 5ei1 B 336-337 disorder
       Region 5ei1 B 338-459 order
       Region 5ei1 B 460-468 disorder
       Region 5ei1 B 469-549 order
       Region 5ei1 B 550-554 disorder
 Evidence X-RAY 5ei1 A Reference
       Region 5ei1 A 298-305 disorder
       Region 5ei1 A 306-332 order
       Region 5ei1 A 333-334 disorder
       Region 5ei1 A 335-461 order
       Region 5ei1 A 462-470 disorder
       Region 5ei1 A 471-548 order
       Region 5ei1 A 549-554 disorder
 Evidence X-RAY 5ehj B Reference
       Region 5ehj B 298-304 disorder
       Region 5ehj B 305-336 order
       Region 5ehj B 337-337 disorder
       Region 5ehj B 338-413 order
       Region 5ehj B 414-417 disorder
       Region 5ehj B 418-461 order
       Region 5ehj B 462-466 disorder
       Region 5ehj B 467-548 order
       Region 5ehj B 549-554 disorder
 Evidence X-RAY 5ehj A Reference
       Region 5ehj A 298-304 disorder
       Region 5ehj A 305-416 order
       Region 5ehj A 417-420 disorder
       Region 5ehj A 421-459 order
       Region 5ehj A 460-470 disorder
       Region 5ehj A 471-548 order
       Region 5ehj A 549-554 disorder
 Evidence X-RAY 5egv B Reference
       Region 5egv B 298-307 disorder
       Region 5egv B 308-334 order
       Region 5egv B 335-336 disorder
       Region 5egv B 337-461 order
       Region 5egv B 462-469 disorder
       Region 5egv B 470-549 order
       Region 5egv B 550-554 disorder
 Evidence X-RAY 5egv A Reference
       Region 5egv A 298-303 disorder
       Region 5egv A 304-330 order
       Region 5egv A 331-336 disorder
       Region 5egv A 337-460 order
       Region 5egv A 461-470 disorder
       Region 5egv A 471-548 order
       Region 5egv A 549-554 disorder
 Evidence X-RAY 5e1c B Reference
       Region 5e1c B 298-304 disorder
       Region 5e1c B 305-461 order
       Region 5e1c B 462-464 disorder
       Region 5e1c B 465-548 order
       Region 5e1c B 549-554 disorder
 Evidence X-RAY 5e1c A Reference
       Region 5e1c A 298-303 disorder
       Region 5e1c A 304-332 order
       Region 5e1c A 333-333 disorder
       Region 5e1c A 334-461 order
       Region 5e1c A 462-469 disorder
       Region 5e1c A 470-549 order
       Region 5e1c A 550-554 disorder
 Evidence X-RAY 5e19 B Reference
       Region 5e19 B 298-304 disorder
       Region 5e19 B 305-461 order
       Region 5e19 B 462-467 disorder
       Region 5e19 B 468-548 order
       Region 5e19 B 549-554 disorder
 Evidence X-RAY 5e19 A Reference
       Region 5e19 A 298-304 disorder
       Region 5e19 A 305-460 order
       Region 5e19 A 461-471 disorder
       Region 5e19 A 472-548 order
       Region 5e19 A 549-554 disorder
 Evidence X-RAY 5e15 B Reference
       Region 5e15 B 298-304 disorder
       Region 5e15 B 305-418 order
       Region 5e15 B 419-420 disorder
       Region 5e15 B 421-460 order
       Region 5e15 B 461-467 disorder
       Region 5e15 B 468-529 order
       Region 5e15 B 530-532 disorder
       Region 5e15 B 533-549 order
       Region 5e15 B 550-554 disorder
 Evidence X-RAY 5e15 A Reference
       Region 5e15 A 298-302 disorder
       Region 5e15 A 303-331 order
       Region 5e15 A 332-340 disorder
       Region 5e15 A 341-414 order
       Region 5e15 A 415-420 disorder
       Region 5e15 A 421-458 order
       Region 5e15 A 459-471 disorder
       Region 5e15 A 472-548 order
       Region 5e15 A 549-554 disorder
 Evidence X-RAY 5e14 B Reference
       Region 5e14 B 298-304 disorder
       Region 5e14 B 305-461 order
       Region 5e14 B 462-466 disorder
       Region 5e14 B 467-528 order
       Region 5e14 B 529-531 disorder
       Region 5e14 B 532-549 order
       Region 5e14 B 550-554 disorder
 Evidence X-RAY 5e14 A Reference
       Region 5e14 A 298-304 disorder
       Region 5e14 A 305-334 order
       Region 5e14 A 335-336 disorder
       Region 5e14 A 337-461 order
       Region 5e14 A 462-471 disorder
       Region 5e14 A 472-548 order
       Region 5e14 A 549-554 disorder
 Evidence X-RAY 5e0x B Reference
       Region 5e0x B 298-304 disorder
       Region 5e0x B 305-331 order
       Region 5e0x B 332-335 disorder
       Region 5e0x B 336-461 order
       Region 5e0x B 462-471 disorder
       Region 5e0x B 472-548 order
       Region 5e0x B 549-554 disorder
 Evidence X-RAY 5e0x A Reference
       Region 5e0x A 298-304 disorder
       Region 5e0x A 305-461 order
       Region 5e0x A 462-470 disorder
       Region 5e0x A 471-529 order
       Region 5e0x A 530-534 disorder
       Region 5e0x A 535-548 order
       Region 5e0x A 549-554 disorder
 Evidence X-RAY 5e0w B Reference
       Region 5e0w B 298-304 disorder
       Region 5e0w B 305-330 order
       Region 5e0w B 331-333 disorder
       Region 5e0w B 334-460 order
       Region 5e0w B 461-471 disorder
       Region 5e0w B 472-548 order
       Region 5e0w B 549-554 disorder
 Evidence X-RAY 5e0w A Reference
       Region 5e0w A 298-304 disorder
       Region 5e0w A 305-460 order
       Region 5e0w A 461-465 disorder
       Region 5e0w A 466-530 order
       Region 5e0w A 531-535 disorder
       Region 5e0w A 536-548 order
       Region 5e0w A 549-554 disorder
 Evidence X-RAY 5dzi B Reference
       Region 5dzi B 298-305 disorder
       Region 5dzi B 306-462 order
       Region 5dzi B 463-466 disorder
       Region 5dzi B 467-548 order
       Region 5dzi B 549-554 disorder
 Evidence X-RAY 5dzi A Reference
       Region 5dzi A 298-303 disorder
       Region 5dzi A 304-461 order
       Region 5dzi A 462-471 disorder
       Region 5dzi A 472-548 order
       Region 5dzi A 549-554 disorder
 Evidence X-RAY 5dzh B Reference
       Region 5dzh B 298-304 disorder
       Region 5dzh B 305-414 order
       Region 5dzh B 415-418 disorder
       Region 5dzh B 419-461 order
       Region 5dzh B 462-466 disorder
       Region 5dzh B 467-531 order
       Region 5dzh B 532-533 disorder
       Region 5dzh B 534-550 order
       Region 5dzh B 551-554 disorder
 Evidence X-RAY 5dzh A Reference
       Region 5dzh A 298-303 disorder
       Region 5dzh A 304-460 order
       Region 5dzh A 461-471 disorder
       Region 5dzh A 472-549 order
       Region 5dzh A 550-554 disorder
 Evidence X-RAY 5dz3 B Reference
       Region 5dz3 B 298-304 disorder
       Region 5dz3 B 305-414 order
       Region 5dz3 B 415-416 disorder
       Region 5dz3 B 417-459 order
       Region 5dz3 B 460-464 disorder
       Region 5dz3 B 465-549 order
       Region 5dz3 B 550-554 disorder
 Evidence X-RAY 5dz3 A Reference
       Region 5dz3 A 298-304 disorder
       Region 5dz3 A 305-331 order
       Region 5dz3 A 332-333 disorder
       Region 5dz3 A 334-459 order
       Region 5dz3 A 460-471 disorder
       Region 5dz3 A 472-549 order
       Region 5dz3 A 550-554 disorder
 Evidence X-RAY 5dz1 B Reference
       Region 5dz1 B 298-304 disorder
       Region 5dz1 B 305-461 order
       Region 5dz1 B 462-464 disorder
       Region 5dz1 B 465-548 order
       Region 5dz1 B 549-554 disorder
 Evidence X-RAY 5dz1 A Reference
       Region 5dz1 A 298-302 disorder
       Region 5dz1 A 303-459 order
       Region 5dz1 A 460-472 disorder
       Region 5dz1 A 473-530 order
       Region 5dz1 A 531-531 disorder
       Region 5dz1 A 532-548 order
       Region 5dz1 A 549-554 disorder
 Evidence X-RAY 5dz0 B Reference
       Region 5dz0 B 298-304 disorder
       Region 5dz0 B 305-415 order
       Region 5dz0 B 416-420 disorder
       Region 5dz0 B 421-459 order
       Region 5dz0 B 460-465 disorder
       Region 5dz0 B 466-549 order
       Region 5dz0 B 550-554 disorder
 Evidence X-RAY 5dz0 A Reference
       Region 5dz0 A 298-303 disorder
       Region 5dz0 A 304-460 order
       Region 5dz0 A 461-469 disorder
       Region 5dz0 A 470-548 order
       Region 5dz0 A 549-554 disorder
 Evidence X-RAY 5dyd B Reference
       Region 5dyd B 298-307 disorder
       Region 5dyd B 308-336 order
       Region 5dyd B 337-339 disorder
       Region 5dyd B 340-461 order
       Region 5dyd B 462-467 disorder
       Region 5dyd B 468-531 order
       Region 5dyd B 532-532 disorder
       Region 5dyd B 533-548 order
       Region 5dyd B 549-554 disorder
 Evidence X-RAY 5dyd A Reference
       Region 5dyd A 298-305 disorder
       Region 5dyd A 306-331 order
       Region 5dyd A 332-336 disorder
       Region 5dyd A 337-460 order
       Region 5dyd A 461-472 disorder
       Region 5dyd A 473-532 order
       Region 5dyd A 533-533 disorder
       Region 5dyd A 534-548 order
       Region 5dyd A 549-554 disorder
 Evidence X-RAY 5dyb B Reference
       Region 5dyb B 298-304 disorder
       Region 5dyb B 305-416 order
       Region 5dyb B 417-420 disorder
       Region 5dyb B 421-460 order
       Region 5dyb B 461-466 disorder
       Region 5dyb B 467-548 order
       Region 5dyb B 549-554 disorder
 Evidence X-RAY 5dyb A Reference
       Region 5dyb A 298-304 disorder
       Region 5dyb A 305-331 order
       Region 5dyb A 332-333 disorder
       Region 5dyb A 334-459 order
       Region 5dyb A 460-472 disorder
       Region 5dyb A 473-548 order
       Region 5dyb A 549-554 disorder
 Evidence X-RAY 5dy8 B Reference
       Region 5dy8 B 298-304 disorder
       Region 5dy8 B 305-413 order
       Region 5dy8 B 414-418 disorder
       Region 5dy8 B 419-460 order
       Region 5dy8 B 461-465 disorder
       Region 5dy8 B 466-549 order
       Region 5dy8 B 550-554 disorder
 Evidence X-RAY 5dy8 A Reference
       Region 5dy8 A 298-303 disorder
       Region 5dy8 A 304-459 order
       Region 5dy8 A 460-471 disorder
       Region 5dy8 A 472-548 order
       Region 5dy8 A 549-554 disorder
 Evidence X-RAY 5dxr B Reference
       Region 5dxr B 298-304 disorder
       Region 5dxr B 305-461 order
       Region 5dxr B 462-469 disorder
       Region 5dxr B 470-548 order
       Region 5dxr B 549-554 disorder
 Evidence X-RAY 5dxr A Reference
       Region 5dxr A 298-303 disorder
       Region 5dxr A 304-461 order
       Region 5dxr A 462-471 disorder
       Region 5dxr A 472-548 order
       Region 5dxr A 549-554 disorder
 Evidence X-RAY 5dxq B Reference
       Region 5dxq B 298-303 disorder
       Region 5dxq B 304-415 order
       Region 5dxq B 416-417 disorder
       Region 5dxq B 418-460 order
       Region 5dxq B 461-471 disorder
       Region 5dxq B 472-548 order
       Region 5dxq B 549-554 disorder
 Evidence X-RAY 5dxq A Reference
       Region 5dxq A 298-305 disorder
       Region 5dxq A 306-331 order
       Region 5dxq A 332-336 disorder
       Region 5dxq A 337-461 order
       Region 5dxq A 462-471 disorder
       Region 5dxq A 472-532 order
       Region 5dxq A 533-533 disorder
       Region 5dxq A 534-548 order
       Region 5dxq A 549-554 disorder
 Evidence X-RAY 5dxp B Reference
       Region 5dxp B 298-305 disorder
       Region 5dxp B 306-418 order
       Region 5dxp B 419-420 disorder
       Region 5dxp B 421-459 order
       Region 5dxp B 460-470 disorder
       Region 5dxp B 471-548 order
       Region 5dxp B 549-554 disorder
 Evidence X-RAY 5dxp A Reference
       Region 5dxp A 298-304 disorder
       Region 5dxp A 305-332 order
       Region 5dxp A 333-340 disorder
       Region 5dxp A 341-459 order
       Region 5dxp A 460-472 disorder
       Region 5dxp A 473-547 order
       Region 5dxp A 548-554 disorder
 Evidence X-RAY 5dxm B Reference
       Region 5dxm B 298-304 disorder
       Region 5dxm B 305-461 order
       Region 5dxm B 462-467 disorder
       Region 5dxm B 468-547 order
       Region 5dxm B 548-554 disorder
 Evidence X-RAY 5dxm A Reference
       Region 5dxm A 298-304 disorder
       Region 5dxm A 305-461 order
       Region 5dxm A 462-471 disorder
       Region 5dxm A 472-548 order
       Region 5dxm A 549-554 disorder
 Evidence X-RAY 5dxk B Reference
       Region 5dxk B 298-304 disorder
       Region 5dxk B 305-461 order
       Region 5dxk B 462-467 disorder
       Region 5dxk B 468-549 order
       Region 5dxk B 550-554 disorder
 Evidence X-RAY 5dxk A Reference
       Region 5dxk A 298-304 disorder
       Region 5dxk A 305-461 order
       Region 5dxk A 462-471 disorder
       Region 5dxk A 472-548 order
       Region 5dxk A 549-554 disorder
 Evidence X-RAY 5dwj B Reference
       Region 5dwj B 298-304 disorder
       Region 5dwj B 305-336 order
       Region 5dwj B 337-337 disorder
       Region 5dwj B 338-414 order
       Region 5dwj B 415-420 disorder
       Region 5dwj B 421-460 order
       Region 5dwj B 461-469 disorder
       Region 5dwj B 470-549 order
       Region 5dwj B 550-554 disorder
 Evidence X-RAY 5dwj A Reference
       Region 5dwj A 298-304 disorder
       Region 5dwj A 305-333 order
       Region 5dwj A 334-336 disorder
       Region 5dwj A 337-461 order
       Region 5dwj A 462-471 disorder
       Region 5dwj A 472-548 order
       Region 5dwj A 549-554 disorder
 Evidence X-RAY 5dwi B Reference
       Region 5dwi B 298-304 disorder
       Region 5dwi B 305-335 order
       Region 5dwi B 336-337 disorder
       Region 5dwi B 338-460 order
       Region 5dwi B 461-469 disorder
       Region 5dwi B 470-532 order
       Region 5dwi B 533-534 disorder
       Region 5dwi B 535-548 order
       Region 5dwi B 549-554 disorder
 Evidence X-RAY 5dwi A Reference
       Region 5dwi A 298-304 disorder
       Region 5dwi A 305-334 order
       Region 5dwi A 335-336 disorder
       Region 5dwi A 337-460 order
       Region 5dwi A 461-470 disorder
       Region 5dwi A 471-548 order
       Region 5dwi A 549-554 disorder
 Evidence X-RAY 5dwg B Reference
       Region 5dwg B 298-309 disorder
       Region 5dwg B 310-332 order
       Region 5dwg B 333-337 disorder
       Region 5dwg B 338-416 order
       Region 5dwg B 417-419 disorder
       Region 5dwg B 420-459 order
       Region 5dwg B 460-469 disorder
       Region 5dwg B 470-531 order
       Region 5dwg B 532-535 disorder
       Region 5dwg B 536-547 order
       Region 5dwg B 548-554 disorder
 Evidence X-RAY 5dwg A Reference
       Region 5dwg A 298-304 disorder
       Region 5dwg A 305-330 order
       Region 5dwg A 331-336 disorder
       Region 5dwg A 337-419 order
       Region 5dwg A 420-420 disorder
       Region 5dwg A 421-460 order
       Region 5dwg A 461-471 disorder
       Region 5dwg A 472-532 order
       Region 5dwg A 533-533 disorder
       Region 5dwg A 534-548 order
       Region 5dwg A 549-554 disorder
 Evidence X-RAY 5dwe B Reference
       Region 5dwe B 298-304 disorder
       Region 5dwe B 305-336 order
       Region 5dwe B 337-337 disorder
       Region 5dwe B 338-414 order
       Region 5dwe B 415-419 disorder
       Region 5dwe B 420-460 order
       Region 5dwe B 461-470 disorder
       Region 5dwe B 471-549 order
       Region 5dwe B 550-554 disorder
 Evidence X-RAY 5dwe A Reference
       Region 5dwe A 298-304 disorder
       Region 5dwe A 305-333 order
       Region 5dwe A 334-335 disorder
       Region 5dwe A 336-461 order
       Region 5dwe A 462-471 disorder
       Region 5dwe A 472-552 order
       Region 5dwe A 553-554 disorder
 Evidence X-RAY 5dvv B Reference
       Region 5dvv B 298-308 disorder
       Region 5dvv B 309-331 order
       Region 5dvv B 332-340 disorder
       Region 5dvv B 341-411 order
       Region 5dvv B 412-419 disorder
       Region 5dvv B 420-460 order
       Region 5dvv B 461-472 disorder
       Region 5dvv B 473-547 order
       Region 5dvv B 548-554 disorder
 Evidence X-RAY 5dvv A Reference
       Region 5dvv A 298-309 disorder
       Region 5dvv A 310-330 order
       Region 5dvv A 331-339 disorder
       Region 5dvv A 340-412 order
       Region 5dvv A 413-421 disorder
       Region 5dvv A 422-460 order
       Region 5dvv A 461-466 disorder
       Region 5dvv A 467-527 order
       Region 5dvv A 528-533 disorder
       Region 5dvv A 534-548 order
       Region 5dvv A 549-554 disorder
 Evidence X-RAY 5dvs B Reference
       Region 5dvs B 298-305 disorder
       Region 5dvs B 306-336 order
       Region 5dvs B 337-338 disorder
       Region 5dvs B 339-414 order
       Region 5dvs B 415-420 disorder
       Region 5dvs B 421-460 order
       Region 5dvs B 461-471 disorder
       Region 5dvs B 472-532 order
       Region 5dvs B 533-533 disorder
       Region 5dvs B 534-548 order
       Region 5dvs B 549-554 disorder
 Evidence X-RAY 5dvs A Reference
       Region 5dvs A 298-305 disorder
       Region 5dvs A 306-334 order
       Region 5dvs A 335-335 disorder
       Region 5dvs A 336-461 order
       Region 5dvs A 462-471 disorder
       Region 5dvs A 472-547 order
       Region 5dvs A 548-554 disorder
 Evidence X-RAY 5duh B Reference
       Region 5duh B 298-304 disorder
       Region 5duh B 305-334 order
       Region 5duh B 335-336 disorder
       Region 5duh B 337-459 order
       Region 5duh B 460-469 disorder
       Region 5duh B 470-549 order
       Region 5duh B 550-554 disorder
 Evidence X-RAY 5duh A Reference
       Region 5duh A 298-304 disorder
       Region 5duh A 305-461 order
       Region 5duh A 462-469 disorder
       Region 5duh A 470-548 order
       Region 5duh A 549-554 disorder
 Evidence X-RAY 5dug B Reference
       Region 5dug B 298-304 disorder
       Region 5dug B 305-459 order
       Region 5dug B 460-469 disorder
       Region 5dug B 470-548 order
       Region 5dug B 549-554 disorder
 Evidence X-RAY 5dug A Reference
       Region 5dug A 298-305 disorder
       Region 5dug A 306-461 order
       Region 5dug A 462-470 disorder
       Region 5dug A 471-548 order
       Region 5dug A 549-554 disorder
 Evidence X-RAY 5due B Reference
       Region 5due B 298-303 disorder
       Region 5due B 304-461 order
       Region 5due B 462-465 disorder
       Region 5due B 466-549 order
       Region 5due B 550-554 disorder
 Evidence X-RAY 5due A Reference
       Region 5due A 298-304 disorder
       Region 5due A 305-462 order
       Region 5due A 463-471 disorder
       Region 5due A 472-548 order
       Region 5due A 549-554 disorder
 Evidence X-RAY 5du5 B Reference
       Region 5du5 B 298-305 disorder
       Region 5du5 B 306-461 order
       Region 5du5 B 462-468 disorder
       Region 5du5 B 469-532 order
       Region 5du5 B 533-534 disorder
       Region 5du5 B 535-549 order
       Region 5du5 B 550-554 disorder
 Evidence X-RAY 5du5 A Reference
       Region 5du5 A 298-304 disorder
       Region 5du5 A 305-331 order
       Region 5du5 A 332-335 disorder
       Region 5du5 A 336-461 order
       Region 5du5 A 462-470 disorder
       Region 5du5 A 471-548 order
       Region 5du5 A 549-554 disorder
 Evidence X-RAY 5dtv B Reference
       Region 5dtv B 298-304 disorder
       Region 5dtv B 305-461 order
       Region 5dtv B 462-467 disorder
       Region 5dtv B 468-548 order
       Region 5dtv B 549-554 disorder
 Evidence X-RAY 5dtv A Reference
       Region 5dtv A 298-304 disorder
       Region 5dtv A 305-332 order
       Region 5dtv A 333-335 disorder
       Region 5dtv A 336-460 order
       Region 5dtv A 461-471 disorder
       Region 5dtv A 472-548 order
       Region 5dtv A 549-554 disorder
 Evidence X-RAY 5drm B Reference
       Region 5drm B 298-304 disorder
       Region 5drm B 305-331 order
       Region 5drm B 332-336 disorder
       Region 5drm B 337-462 order
       Region 5drm B 463-463 disorder
       Region 5drm B 464-529 order
       Region 5drm B 530-532 disorder
       Region 5drm B 533-548 order
       Region 5drm B 549-554 disorder
 Evidence X-RAY 5drm A Reference
       Region 5drm A 298-304 disorder
       Region 5drm A 305-460 order
       Region 5drm A 461-465 disorder
       Region 5drm A 466-548 order
       Region 5drm A 549-554 disorder
 Evidence X-RAY 5drj B Reference
       Region 5drj B 298-304 disorder
       Region 5drj B 305-461 order
       Region 5drj B 462-464 disorder
       Region 5drj B 465-549 order
       Region 5drj B 550-554 disorder
 Evidence X-RAY 5drj A Reference
       Region 5drj A 298-304 disorder
       Region 5drj A 305-461 order
       Region 5drj A 462-471 disorder
       Region 5drj A 472-548 order
       Region 5drj A 549-554 disorder
 Evidence X-RAY 5dp0 B Reference
       Region 5dp0 B 298-304 disorder
       Region 5dp0 B 305-414 order
       Region 5dp0 B 415-420 disorder
       Region 5dp0 B 421-461 order
       Region 5dp0 B 462-467 disorder
       Region 5dp0 B 468-548 order
       Region 5dp0 B 549-554 disorder
 Evidence X-RAY 5dp0 A Reference
       Region 5dp0 A 298-304 disorder
       Region 5dp0 A 305-331 order
       Region 5dp0 A 332-334 disorder
       Region 5dp0 A 335-414 order
       Region 5dp0 A 415-416 disorder
       Region 5dp0 A 417-461 order
       Region 5dp0 A 462-471 disorder
       Region 5dp0 A 472-548 order
       Region 5dp0 A 549-554 disorder
 Evidence X-RAY 5dmf B Reference
       Region 5dmf B 298-305 disorder
       Region 5dmf B 306-459 order
       Region 5dmf B 460-469 disorder
       Region 5dmf B 470-548 order
       Region 5dmf B 549-554 disorder
 Evidence X-RAY 5dmf A Reference
       Region 5dmf A 298-304 disorder
       Region 5dmf A 305-461 order
       Region 5dmf A 462-469 disorder
       Region 5dmf A 470-548 order
       Region 5dmf A 549-554 disorder
 Evidence X-RAY 5dmc B Reference
       Region 5dmc B 298-304 disorder
       Region 5dmc B 305-336 order
       Region 5dmc B 337-337 disorder
       Region 5dmc B 338-416 order
       Region 5dmc B 417-419 disorder
       Region 5dmc B 420-461 order
       Region 5dmc B 462-467 disorder
       Region 5dmc B 468-531 order
       Region 5dmc B 532-533 disorder
       Region 5dmc B 534-547 order
       Region 5dmc B 548-554 disorder
 Evidence X-RAY 5dmc A Reference
       Region 5dmc A 298-304 disorder
       Region 5dmc A 305-331 order
       Region 5dmc A 332-336 disorder
       Region 5dmc A 337-418 order
       Region 5dmc A 419-420 disorder
       Region 5dmc A 421-460 order
       Region 5dmc A 461-471 disorder
       Region 5dmc A 472-532 order
       Region 5dmc A 533-534 disorder
       Region 5dmc A 535-547 order
       Region 5dmc A 548-554 disorder
 Evidence X-RAY 5dlr B Reference
       Region 5dlr B 298-304 disorder
       Region 5dlr B 305-416 order
       Region 5dlr B 417-418 disorder
       Region 5dlr B 419-461 order
       Region 5dlr B 462-465 disorder
       Region 5dlr B 466-550 order
       Region 5dlr B 551-554 disorder
 Evidence X-RAY 5dlr A Reference
       Region 5dlr A 298-303 disorder
       Region 5dlr A 304-459 order
       Region 5dlr A 460-471 disorder
       Region 5dlr A 472-548 order
       Region 5dlr A 549-554 disorder
 Evidence X-RAY 5dl4 B Reference
       Region 5dl4 B 298-304 disorder
       Region 5dl4 B 305-461 order
       Region 5dl4 B 462-465 disorder
       Region 5dl4 B 466-548 order
       Region 5dl4 B 549-554 disorder
 Evidence X-RAY 5dl4 A Reference
       Region 5dl4 A 298-303 disorder
       Region 5dl4 A 304-333 order
       Region 5dl4 A 334-335 disorder
       Region 5dl4 A 336-461 order
       Region 5dl4 A 462-469 disorder
       Region 5dl4 A 470-550 order
       Region 5dl4 A 551-554 disorder
 Evidence X-RAY 5dks B Reference
       Region 5dks B 298-306 disorder
       Region 5dks B 307-417 order
       Region 5dks B 418-420 disorder
       Region 5dks B 421-461 order
       Region 5dks B 462-468 disorder
       Region 5dks B 469-529 order
       Region 5dks B 530-534 disorder
       Region 5dks B 535-548 order
       Region 5dks B 549-554 disorder
 Evidence X-RAY 5dks A Reference
       Region 5dks A 298-304 disorder
       Region 5dks A 305-330 order
       Region 5dks A 331-335 disorder
       Region 5dks A 336-461 order
       Region 5dks A 462-470 disorder
       Region 5dks A 471-528 order
       Region 5dks A 529-533 disorder
       Region 5dks A 534-548 order
       Region 5dks A 549-554 disorder
 Evidence X-RAY 5dkg B Reference
       Region 5dkg B 298-304 disorder
       Region 5dkg B 305-460 order
       Region 5dkg B 461-463 disorder
       Region 5dkg B 464-529 order
       Region 5dkg B 530-531 disorder
       Region 5dkg B 532-549 order
       Region 5dkg B 550-554 disorder
 Evidence X-RAY 5dkg A Reference
       Region 5dkg A 298-303 disorder
       Region 5dkg A 304-461 order
       Region 5dkg A 462-471 disorder
       Region 5dkg A 472-530 order
       Region 5dkg A 531-534 disorder
       Region 5dkg A 535-548 order
       Region 5dkg A 549-554 disorder
 Evidence X-RAY 5dke B Reference
       Region 5dke B 298-304 disorder
       Region 5dke B 305-458 order
       Region 5dke B 459-469 disorder
       Region 5dke B 470-528 order
       Region 5dke B 529-532 disorder
       Region 5dke B 533-554 order
 Evidence X-RAY 5dke A Reference
       Region 5dke A 298-304 disorder
       Region 5dke A 305-330 order
       Region 5dke A 331-340 disorder
       Region 5dke A 341-458 order
       Region 5dke A 459-471 disorder
       Region 5dke A 472-548 order
       Region 5dke A 549-554 disorder
 Evidence X-RAY 5dkb B Reference
       Region 5dkb B 298-305 disorder
       Region 5dkb B 306-459 order
       Region 5dkb B 460-469 disorder
       Region 5dkb B 470-533 order
       Region 5dkb B 534-534 disorder
       Region 5dkb B 535-548 order
       Region 5dkb B 549-554 disorder
 Evidence X-RAY 5dkb A Reference
       Region 5dkb A 298-304 disorder
       Region 5dkb A 305-461 order
       Region 5dkb A 462-471 disorder
       Region 5dkb A 472-530 order
       Region 5dkb A 531-534 disorder
       Region 5dkb A 535-548 order
       Region 5dkb A 549-554 disorder
 Evidence X-RAY 5dk9 B Reference
       Region 5dk9 B 298-304 disorder
       Region 5dk9 B 305-460 order
       Region 5dk9 B 461-467 disorder
       Region 5dk9 B 468-532 order
       Region 5dk9 B 533-534 disorder
       Region 5dk9 B 535-548 order
       Region 5dk9 B 549-554 disorder
 Evidence X-RAY 5dk9 A Reference
       Region 5dk9 A 298-305 disorder
       Region 5dk9 A 306-460 order
       Region 5dk9 A 461-472 disorder
       Region 5dk9 A 473-530 order
       Region 5dk9 A 531-531 disorder
       Region 5dk9 A 532-548 order
       Region 5dk9 A 549-554 disorder
 Evidence X-RAY 5dig B Reference
       Region 5dig B 298-304 disorder
       Region 5dig B 305-461 order
       Region 5dig B 462-464 disorder
       Region 5dig B 465-549 order
       Region 5dig B 550-554 disorder
 Evidence X-RAY 5dig A Reference
       Region 5dig A 298-302 disorder
       Region 5dig A 303-461 order
       Region 5dig A 462-468 disorder
       Region 5dig A 469-550 order
       Region 5dig A 551-554 disorder
 Evidence X-RAY 5die B Reference
       Region 5die B 298-304 disorder
       Region 5die B 305-332 order
       Region 5die B 333-334 disorder
       Region 5die B 335-460 order
       Region 5die B 461-466 disorder
       Region 5die B 467-533 order
       Region 5die B 534-534 disorder
       Region 5die B 535-548 order
       Region 5die B 549-554 disorder
 Evidence X-RAY 5die A Reference
       Region 5die A 298-304 disorder
       Region 5die A 305-461 order
       Region 5die A 462-469 disorder
       Region 5die A 470-548 order
       Region 5die A 549-554 disorder
 Evidence X-RAY 5did B Reference
       Region 5did B 298-304 disorder
       Region 5did B 305-549 order
       Region 5did B 550-554 disorder
 Evidence X-RAY 5did A Reference
       Region 5did A 298-304 disorder
       Region 5did A 305-461 order
       Region 5did A 462-463 disorder
       Region 5did A 464-550 order
       Region 5did A 551-554 disorder
 Evidence X-RAY 5di7 B Reference
       Region 5di7 B 298-304 disorder
       Region 5di7 B 305-549 order
       Region 5di7 B 550-554 disorder
 Evidence X-RAY 5di7 A Reference
       Region 5di7 A 298-304 disorder
       Region 5di7 A 305-461 order
       Region 5di7 A 462-464 disorder
       Region 5di7 A 465-548 order
       Region 5di7 A 549-554 disorder
 Evidence X-RAY 2b23 B Reference
       Region 2b23 B 298-304 disorder
       Region 2b23 B 305-461 order
       Region 2b23 B 462-471 disorder
       Region 2b23 B 472-547 order
       Region 2b23 B 548-554 disorder
 Evidence X-RAY 2b23 A Reference
       Region 2b23 A 298-304 disorder
       Region 2b23 A 305-332 order
       Region 2b23 A 333-336 disorder
       Region 2b23 A 337-461 order
       Region 2b23 A 462-472 disorder
       Region 2b23 A 473-548 order
       Region 2b23 A 549-554 disorder
 Evidence X-RAY 2b1z B Reference
       Region 2b1z B 298-304 disorder
       Region 2b1z B 305-462 order
       Region 2b1z B 463-466 disorder
       Region 2b1z B 467-470 order
       Region 2b1z B 471-471 disorder
       Region 2b1z B 472-547 order
       Region 2b1z B 548-554 disorder
 Evidence X-RAY 2b1z A Reference
       Region 2b1z A 298-304 disorder
       Region 2b1z A 305-461 order
       Region 2b1z A 462-470 disorder
       Region 2b1z A 471-548 order
       Region 2b1z A 549-554 disorder
 Evidence X-RAY 2b1v B Reference
       Region 2b1v B 298-304 disorder
       Region 2b1v B 305-547 order
       Region 2b1v B 548-548 disorder
       Region 2b1v B 549-549 order
       Region 2b1v B 550-554 disorder
 Evidence X-RAY 2b1v A Reference
       Region 2b1v A 298-304 disorder
       Region 2b1v A 305-461 order
       Region 2b1v A 462-469 disorder
       Region 2b1v A 470-548 order
       Region 2b1v A 549-554 disorder
Seq 298-307 Hetero dimer : IID00128Complex
 Evidence X-RAY 3cbp B Reference
       Region 3cbp B 298-298 disorder
       Region 3cbp B 299-302 order
       Region 3cbp B 303-307 disorder
 Evidence X-RAY 3cbo B Reference
       Region 3cbo B 298-298 disorder
       Region 3cbo B 299-303 order
       Region 3cbo B 304-307 disorder
 Evidence X-RAY 3cbm B Reference
       Region 3cbm B 298-304 order
       Region 3cbm B 305-307 disorder
Seq 298-550 Hetero dimer : IID50249Complex
 Evidence X-RAY 3l03 B Reference
       Region 3l03 B 298-304 disorder
       Region 3l03 B 305-463 order
       Region 3l03 B 464-466 disorder
       Region 3l03 B 467-550 order
 Evidence X-RAY 3l03 A Reference
       Region 3l03 A 298-304 disorder
       Region 3l03 A 305-460 order
       Region 3l03 A 461-468 disorder
       Region 3l03 A 469-548 order
       Region 3l03 A 549-550 disorder
Seq 298-550 Hetero tetramer : IID50249Complex
 Evidence X-RAY 3hm1 B Reference
       Region 3hm1 B 298-302 disorder
       Region 3hm1 B 303-462 order
       Region 3hm1 B 463-471 disorder
       Region 3hm1 B 472-550 order
 Evidence X-RAY 3hm1 A Reference
       Region 3hm1 A 298-305 disorder
       Region 3hm1 A 306-461 order
       Region 3hm1 A 462-469 disorder
       Region 3hm1 A 470-548 order
       Region 3hm1 A 549-550 disorder
 Evidence X-RAY 3hlv B Reference
       Region 3hlv B 298-303 disorder
       Region 3hlv B 304-462 order
       Region 3hlv B 463-467 disorder
       Region 3hlv B 468-548 order
       Region 3hlv B 549-550 disorder
 Evidence X-RAY 3hlv A Reference
       Region 3hlv A 298-303 disorder
       Region 3hlv A 304-332 order
       Region 3hlv A 333-335 disorder
       Region 3hlv A 336-462 order
       Region 3hlv A 463-464 disorder
       Region 3hlv A 465-548 order
       Region 3hlv A 549-550 disorder
Seq 298-595 Hetero tetramer : P02751
 Evidence X-RAY 2ocf A Reference
       Region 2ocf A 298-304 disorder
       Region 2ocf A 305-460 order
       Region 2ocf A 461-471 disorder
       Region 2ocf A 472-548 order
       Region 2ocf A 549-595 disorder
Seq 299-553 Homo tetramer :
 Evidence X-RAY 3osa D Reference
       Region 3osa D 299-304 disorder
       Region 3osa D 305-331 order
       Region 3osa D 332-340 disorder
       Region 3osa D 341-415 order
       Region 3osa D 416-418 disorder
       Region 3osa D 419-461 order
       Region 3osa D 462-466 disorder
       Region 3osa D 467-547 order
       Region 3osa D 548-553 disorder
 Evidence X-RAY 3osa C Reference
       Region 3osa C 299-304 disorder
       Region 3osa C 305-331 order
       Region 3osa C 332-340 disorder
       Region 3osa C 341-415 order
       Region 3osa C 416-418 disorder
       Region 3osa C 419-546 order
       Region 3osa C 547-553 disorder
 Evidence X-RAY 3osa B Reference
       Region 3osa B 299-305 disorder
       Region 3osa B 306-416 order
       Region 3osa B 417-417 disorder
       Region 3osa B 418-531 order
       Region 3osa B 532-532 disorder
       Region 3osa B 533-546 order
       Region 3osa B 547-553 disorder
 Evidence X-RAY 3osa A Reference
       Region 3osa A 299-305 disorder
       Region 3osa A 306-416 order
       Region 3osa A 417-417 disorder
       Region 3osa A 418-530 order
       Region 3osa A 531-531 disorder
       Region 3osa A 532-546 order
       Region 3osa A 547-553 disorder
 Evidence X-RAY 3os8 D Reference
       Region 3os8 D 299-304 disorder
       Region 3os8 D 305-332 order
       Region 3os8 D 333-340 disorder
       Region 3os8 D 341-461 order
       Region 3os8 D 462-466 disorder
       Region 3os8 D 467-547 order
       Region 3os8 D 548-553 disorder
 Evidence X-RAY 3os8 C Reference
       Region 3os8 C 299-304 disorder
       Region 3os8 C 305-332 order
       Region 3os8 C 333-340 disorder
       Region 3os8 C 341-546 order
       Region 3os8 C 547-553 disorder
 Evidence X-RAY 3os8 B Reference
       Region 3os8 B 299-305 disorder
       Region 3os8 B 306-546 order
       Region 3os8 B 547-553 disorder
 Evidence X-RAY 3os8 A Reference
       Region 3os8 A 299-305 disorder
       Region 3os8 A 306-546 order
       Region 3os8 A 547-553 disorder
Seq 299-553 Homo tetramer :
 Evidence X-RAY 3os9 A Reference
       Region 3os9 A 299-306 disorder
       Region 3os9 A 307-461 order
       Region 3os9 A 462-463 disorder
       Region 3os9 A 464-472 order
       Region 3os9 A 473-473 disorder
       Region 3os9 A 474-528 order
       Region 3os9 A 529-532 disorder
       Region 3os9 A 533-546 order
       Region 3os9 A 547-553 disorder
 Evidence X-RAY 3os9 B Reference
       Region 3os9 B 299-305 disorder
       Region 3os9 B 306-415 order
       Region 3os9 B 416-418 disorder
       Region 3os9 B 419-461 order
       Region 3os9 B 462-467 disorder
       Region 3os9 B 468-528 order
       Region 3os9 B 529-532 disorder
       Region 3os9 B 533-546 order
       Region 3os9 B 547-553 disorder
 Evidence X-RAY 3os9 C Reference
       Region 3os9 C 299-304 disorder
       Region 3os9 C 305-331 order
       Region 3os9 C 332-340 disorder
       Region 3os9 C 341-414 order
       Region 3os9 C 415-420 disorder
       Region 3os9 C 421-461 order
       Region 3os9 C 462-462 disorder
       Region 3os9 C 463-527 order
       Region 3os9 C 528-532 disorder
       Region 3os9 C 533-546 order
       Region 3os9 C 547-553 disorder
 Evidence X-RAY 3os9 D Reference
       Region 3os9 D 299-305 disorder
       Region 3os9 D 306-330 order
       Region 3os9 D 331-340 disorder
       Region 3os9 D 341-414 order
       Region 3os9 D 415-420 disorder
       Region 3os9 D 421-460 order
       Region 3os9 D 461-468 disorder
       Region 3os9 D 469-526 order
       Region 3os9 D 527-533 disorder
       Region 3os9 D 534-544 order
       Region 3os9 D 545-553 disorder
Seq 301-550 Homo trimer :
 Evidence X-RAY 1qku A Reference
       Region 1qku A 301-550 order
 Evidence X-RAY 1qku B Reference
       Region 1qku B 301-303 disorder
       Region 1qku B 304-550 order
 Evidence X-RAY 1qku C Reference
       Region 1qku C 301-303 disorder
       Region 1qku C 304-550 order
Seq 302-552 Hetero dimer : IID00083Complex
 Evidence X-RAY 3uud B Reference
       Region 3uud B 302-303 disorder
       Region 3uud B 304-461 order
       Region 3uud B 462-471 disorder
       Region 3uud B 472-550 order
       Region 3uud B 551-552 disorder
 Evidence X-RAY 3uud A Reference
       Region 3uud A 302-304 disorder
       Region 3uud A 305-461 order
       Region 3uud A 462-464 disorder
       Region 3uud A 465-549 order
       Region 3uud A 550-552 disorder
 Evidence X-RAY 3uua B Reference
       Region 3uua B 302-304 disorder
       Region 3uua B 305-331 order
       Region 3uua B 332-335 disorder
       Region 3uua B 336-461 order
       Region 3uua B 462-471 disorder
       Region 3uua B 472-548 order
       Region 3uua B 549-552 disorder
 Evidence X-RAY 3uua A Reference
       Region 3uua A 302-304 disorder
       Region 3uua A 305-461 order
       Region 3uua A 462-463 disorder
       Region 3uua A 464-548 order
       Region 3uua A 549-552 disorder
 Evidence X-RAY 3uu7 B Reference
       Region 3uu7 B 302-303 disorder
       Region 3uu7 B 304-461 order
       Region 3uu7 B 462-471 disorder
       Region 3uu7 B 472-548 order
       Region 3uu7 B 549-552 disorder
 Evidence X-RAY 3uu7 A Reference
       Region 3uu7 A 302-305 disorder
       Region 3uu7 A 306-461 order
       Region 3uu7 A 462-466 disorder
       Region 3uu7 A 467-549 order
       Region 3uu7 A 550-552 disorder
Seq 302-552 Hetero tetramer : IID00083Complex
 Evidence X-RAY 4tv1 B Reference
       Region 4tv1 B 302-305 disorder
       Region 4tv1 B 306-335 order
       Region 4tv1 B 336-336 disorder
       Region 4tv1 B 337-461 order
       Region 4tv1 B 462-470 disorder
       Region 4tv1 B 471-548 order
       Region 4tv1 B 549-552 disorder
 Evidence X-RAY 4tv1 A Reference
       Region 4tv1 A 302-304 disorder
       Region 4tv1 A 305-461 order
       Region 4tv1 A 462-469 disorder
       Region 4tv1 A 470-548 order
       Region 4tv1 A 549-552 disorder
 Evidence X-RAY 4tuz B Reference
       Region 4tuz B 302-304 disorder
       Region 4tuz B 305-462 order
       Region 4tuz B 463-463 disorder
       Region 4tuz B 464-549 order
       Region 4tuz B 550-552 disorder
 Evidence X-RAY 4tuz A Reference
       Region 4tuz A 302-304 disorder
       Region 4tuz A 305-461 order
       Region 4tuz A 462-469 disorder
       Region 4tuz A 470-549 order
       Region 4tuz A 550-552 disorder
 Evidence X-RAY 4mgd B Reference
       Region 4mgd B 302-302 disorder
       Region 4mgd B 303-461 order
       Region 4mgd B 462-471 disorder
       Region 4mgd B 472-548 order
       Region 4mgd B 549-552 disorder
 Evidence X-RAY 4mgd A Reference
       Region 4mgd A 302-304 disorder
       Region 4mgd A 305-416 order
       Region 4mgd A 417-418 disorder
       Region 4mgd A 419-461 order
       Region 4mgd A 462-463 disorder
       Region 4mgd A 464-549 order
       Region 4mgd A 550-552 disorder
 Evidence X-RAY 4mgc B Reference
       Region 4mgc B 302-304 disorder
       Region 4mgc B 305-461 order
       Region 4mgc B 462-469 disorder
       Region 4mgc B 470-549 order
       Region 4mgc B 550-552 disorder
 Evidence X-RAY 4mgc A Reference
       Region 4mgc A 302-305 disorder
       Region 4mgc A 306-335 order
       Region 4mgc A 336-336 disorder
       Region 4mgc A 337-461 order
       Region 4mgc A 462-466 disorder
       Region 4mgc A 467-549 order
       Region 4mgc A 550-552 disorder
 Evidence X-RAY 4mgb B Reference
       Region 4mgb B 302-302 disorder
       Region 4mgb B 303-333 order
       Region 4mgb B 334-334 disorder
       Region 4mgb B 335-461 order
       Region 4mgb B 462-472 disorder
       Region 4mgb B 473-548 order
       Region 4mgb B 549-552 disorder
 Evidence X-RAY 4mgb A Reference
       Region 4mgb A 302-304 disorder
       Region 4mgb A 305-416 order
       Region 4mgb A 417-418 disorder
       Region 4mgb A 419-461 order
       Region 4mgb A 462-463 disorder
       Region 4mgb A 464-548 order
       Region 4mgb A 549-552 disorder
 Evidence X-RAY 4mga B Reference
       Region 4mga B 302-302 disorder
       Region 4mga B 303-461 order
       Region 4mga B 462-471 disorder
       Region 4mga B 472-548 order
       Region 4mga B 549-552 disorder
 Evidence X-RAY 4mga A Reference
       Region 4mga A 302-304 disorder
       Region 4mga A 305-417 order
       Region 4mga A 418-419 disorder
       Region 4mga A 420-461 order
       Region 4mga A 462-463 disorder
       Region 4mga A 464-549 order
       Region 4mga A 550-552 disorder
 Evidence X-RAY 4mg9 B Reference
       Region 4mg9 B 302-303 disorder
       Region 4mg9 B 304-333 order
       Region 4mg9 B 334-336 disorder
       Region 4mg9 B 337-461 order
       Region 4mg9 B 462-470 disorder
       Region 4mg9 B 471-548 order
       Region 4mg9 B 549-552 disorder
 Evidence X-RAY 4mg9 A Reference
       Region 4mg9 A 302-304 disorder
       Region 4mg9 A 305-461 order
       Region 4mg9 A 462-463 disorder
       Region 4mg9 A 464-548 order
       Region 4mg9 A 549-552 disorder
 Evidence X-RAY 4mg8 B Reference
       Region 4mg8 B 302-302 disorder
       Region 4mg8 B 303-461 order
       Region 4mg8 B 462-471 disorder
       Region 4mg8 B 472-549 order
       Region 4mg8 B 550-552 disorder
 Evidence X-RAY 4mg8 A Reference
       Region 4mg8 A 302-304 disorder
       Region 4mg8 A 305-461 order
       Region 4mg8 A 462-463 disorder
       Region 4mg8 A 464-548 order
       Region 4mg8 A 549-552 disorder
 Evidence X-RAY 4mg7 B Reference
       Region 4mg7 B 302-302 disorder
       Region 4mg7 B 303-461 order
       Region 4mg7 B 462-472 disorder
       Region 4mg7 B 473-548 order
       Region 4mg7 B 549-552 disorder
 Evidence X-RAY 4mg7 A Reference
       Region 4mg7 A 302-304 disorder
       Region 4mg7 A 305-414 order
       Region 4mg7 A 415-418 disorder
       Region 4mg7 A 419-461 order
       Region 4mg7 A 462-463 disorder
       Region 4mg7 A 464-549 order
       Region 4mg7 A 550-552 disorder
 Evidence X-RAY 4mg6 B Reference
       Region 4mg6 B 302-302 disorder
       Region 4mg6 B 303-462 order
       Region 4mg6 B 463-472 disorder
       Region 4mg6 B 473-548 order
       Region 4mg6 B 549-552 disorder
 Evidence X-RAY 4mg6 A Reference
       Region 4mg6 A 302-304 disorder
       Region 4mg6 A 305-414 order
       Region 4mg6 A 415-420 disorder
       Region 4mg6 A 421-461 order
       Region 4mg6 A 462-464 disorder
       Region 4mg6 A 465-548 order
       Region 4mg6 A 549-552 disorder
 Evidence X-RAY 4mg5 B Reference
       Region 4mg5 B 302-302 disorder
       Region 4mg5 B 303-461 order
       Region 4mg5 B 462-471 disorder
       Region 4mg5 B 472-548 order
       Region 4mg5 B 549-552 disorder
 Evidence X-RAY 4mg5 A Reference
       Region 4mg5 A 302-304 disorder
       Region 4mg5 A 305-461 order
       Region 4mg5 A 462-463 disorder
       Region 4mg5 A 464-547 order
       Region 4mg5 A 548-552 disorder
 Evidence X-RAY 5jmm B Reference
       Region 5jmm B 302-303 disorder
       Region 5jmm B 304-461 order
       Region 5jmm B 462-471 disorder
       Region 5jmm B 472-548 order
       Region 5jmm B 549-552 disorder
 Evidence X-RAY 5jmm A Reference
       Region 5jmm A 302-305 disorder
       Region 5jmm A 306-413 order
       Region 5jmm A 414-420 disorder
       Region 5jmm A 421-461 order
       Region 5jmm A 462-466 disorder
       Region 5jmm A 467-548 order
       Region 5jmm A 549-552 disorder
Seq 303-549 Hetero dimer : IID50084Complex
 Evidence X-RAY 4dma B Reference
       Region 4dma B 303-461 order
       Region 4dma B 462-472 disorder
       Region 4dma B 473-548 order
       Region 4dma B 549-549 disorder
 Evidence X-RAY 4dma A Reference
       Region 4dma A 303-304 disorder
       Region 4dma A 305-461 order
       Region 4dma A 462-468 disorder
       Region 4dma A 469-549 order
Seq 304-533 Hetero dodecamer :
 Evidence X-RAY 2jf9 C Reference
       Region 2jf9 C 304-304 disorder
       Region 2jf9 C 305-458 order
       Region 2jf9 C 459-469 disorder
       Region 2jf9 C 470-529 order
       Region 2jf9 C 530-533 disorder
 Evidence X-RAY 2jf9 B Reference
       Region 2jf9 B 304-304 disorder
       Region 2jf9 B 305-332 order
       Region 2jf9 B 333-340 disorder
       Region 2jf9 B 341-460 order
       Region 2jf9 B 461-468 disorder
       Region 2jf9 B 469-529 order
       Region 2jf9 B 530-533 disorder
 Evidence X-RAY 2jf9 A Reference
       Region 2jf9 A 304-304 disorder
       Region 2jf9 A 305-460 order
       Region 2jf9 A 461-469 disorder
       Region 2jf9 A 470-528 order
       Region 2jf9 A 529-533 disorder
Seq 304-533 Hetero tetramer :
 Evidence X-RAY 2jfa A Reference
       Region 2jfa A 304-304 disorder
       Region 2jfa A 305-331 order
       Region 2jfa A 332-335 disorder
       Region 2jfa A 336-529 order
       Region 2jfa A 530-533 disorder
 Evidence X-RAY 2jfa B Reference
       Region 2jfa B 304-305 disorder
       Region 2jfa B 306-528 order
       Region 2jfa B 529-533 disorder
Seq 304-547 Hetero tetramer :
 Evidence X-RAY 1pcg A Reference
       Region 1pcg A 304-334 order
       Region 1pcg A 335-335 disorder
       Region 1pcg A 336-462 order
       Region 1pcg A 463-473 disorder
       Region 1pcg A 474-547 order
 Evidence X-RAY 1pcg B Reference
       Region 1pcg B 304-462 order
       Region 1pcg B 463-463 disorder
       Region 1pcg B 464-547 order
Seq 304-554 Monomer :
 Evidence X-RAY 1qkt A Reference
       Region 1qkt A 304-551 order
 Evidence X-RAY 5fqv A Reference
       Region 5fqv A 307-337 order
       Region 5fqv A 338-340 disorder
       Region 5fqv A 341-461 order
       Region 5fqv A 462-464 disorder
       Region 5fqv A 465-545 order
       Region 5fqv A 546-554 disorder
 Evidence X-RAY 5fqt A Reference
       Region 5fqt A 307-337 order
       Region 5fqt A 338-340 disorder
       Region 5fqt A 341-461 order
       Region 5fqt A 462-464 disorder
       Region 5fqt A 465-545 order
       Region 5fqt A 546-554 disorder
 Evidence X-RAY 5fqs A Reference
       Region 5fqs A 307-337 order
       Region 5fqs A 338-340 disorder
       Region 5fqs A 341-461 order
       Region 5fqs A 462-464 disorder
       Region 5fqs A 465-545 order
       Region 5fqs A 546-554 disorder
 Evidence X-RAY 5fqr A Reference
       Region 5fqr A 307-337 order
       Region 5fqr A 338-340 disorder
       Region 5fqr A 341-461 order
       Region 5fqr A 462-464 disorder
       Region 5fqr A 465-528 order
       Region 5fqr A 529-533 disorder
       Region 5fqr A 534-545 order
       Region 5fqr A 546-554 disorder
 Evidence X-RAY 5fqp A Reference
       Region 5fqp A 307-548 order
       Region 5fqp A 549-554 disorder
 Evidence X-RAY 5acc A Reference
       Region 5acc A 307-337 order
       Region 5acc A 338-340 disorder
       Region 5acc A 341-461 order
       Region 5acc A 462-464 disorder
       Region 5acc A 465-528 order
       Region 5acc A 529-533 disorder
       Region 5acc A 534-545 order
       Region 5acc A 546-554 disorder
 Evidence X-RAY 5gtr A Reference
       Region 5gtr A 305-330 order
       Region 5gtr A 331-337 disorder
       Region 5gtr A 338-547 order
 Evidence X-RAY 5gs4 A Reference
       Region 5gs4 A 305-330 order
       Region 5gs4 A 331-337 disorder
       Region 5gs4 A 338-547 order
 Evidence X-RAY 2ayr A Reference
       Region 2ayr A 304-305 disorder
       Region 2ayr A 306-551 order
Seq 305-533 Hetero tetramer :
 Evidence X-RAY 2bj4 A Reference
       Region 2bj4 A 305-330 order
       Region 2bj4 A 331-335 disorder
       Region 2bj4 A 336-462 order
       Region 2bj4 A 463-463 disorder
       Region 2bj4 A 464-528 order
       Region 2bj4 A 529-533 disorder
 Evidence X-RAY 2bj4 B Reference
       Region 2bj4 B 305-460 order
       Region 2bj4 B 461-464 disorder
       Region 2bj4 B 465-529 order
       Region 2bj4 B 530-533 disorder
Seq 305-549 Hetero tetramer :
 Evidence X-RAY 1x7r A Reference
       Region 1x7r A 305-305 disorder
       Region 1x7r A 306-330 order
       Region 1x7r A 331-337 disorder
       Region 1x7r A 338-547 order
       Region 1x7r A 548-549 disorder
Seq 305-549 Hetero tetramer :
 Evidence X-RAY 1x7e A Reference
       Region 1x7e A 305-461 order
       Region 1x7e A 462-468 disorder
       Region 1x7e A 469-549 order
 Evidence X-RAY 1x7e B Reference
       Region 1x7e B 305-461 order
       Region 1x7e B 462-468 disorder
       Region 1x7e B 469-549 order
Seq 305-549 Hetero dimer : IID00082Complex
 Evidence X-RAY 1gwr B Reference
       Region 1gwr B 305-333 order
       Region 1gwr B 334-335 disorder
       Region 1gwr B 336-461 order
       Region 1gwr B 462-464 disorder
       Region 1gwr B 465-548 order
       Region 1gwr B 549-549 disorder
 Evidence X-RAY 1gwr A Reference
       Region 1gwr A 305-305 disorder
       Region 1gwr A 306-331 order
       Region 1gwr A 332-334 disorder
       Region 1gwr A 335-461 order
       Region 1gwr A 462-464 disorder
       Region 1gwr A 465-549 order
Seq 305-554 Hetero dimer :
 Evidence X-RAY 6cbz B Reference
       Region 6cbz B 305-306 disorder
       Region 6cbz B 307-329 order
       Region 6cbz B 330-336 disorder
       Region 6cbz B 337-460 order
       Region 6cbz B 461-471 disorder
       Region 6cbz B 472-548 order
       Region 6cbz B 549-554 disorder
Seq 305-554 Hetero dimer :
 Evidence X-RAY 6cbz A Reference
       Region 6cbz A 305-308 disorder
       Region 6cbz A 309-460 order
       Region 6cbz A 461-472 disorder
       Region 6cbz A 473-549 order
       Region 6cbz A 550-554 disorder
Seqdisorder 584-595
 Evidence X-RAY 5n10 D Reference
       Region 5n10 D 584-595 disorder
Seq 584-595 Hetero tetramer : IID00038Complex
 Evidence X-RAY 5n10 F Reference
       Region 5n10 F 584-590 disorder
       Region 5n10 F 591-595 order
 Evidence X-RAY 5n10 C Reference
       Region 5n10 C 584-595 order
Seq 585-595 Hetero tetramer : IID00301Complex
 Evidence X-RAY 4jdd B Reference
       Region 4jdd B 585-590 disorder
       Region 4jdd B 591-595 order
 Evidence X-RAY 4jc3 B Reference
       Region 4jc3 B 585-590 disorder
       Region 4jc3 B 591-595 order
SeqProS verified 220-236 This region is ordered when this protein binds upon DNA as a dimer. Homo dimer :
       Region 1hcq A 180-252 order
       Region 1hcq B 182-252 order
       Region 1hcq E 180-252 order
       Region 1hcq F 218-252 order
       Region 220-236 disorder
SeqProS verified 297-305 Hetero trimer : IID50309Complex
       Region 5t0x B 287-305 order
       Region 5t0x C 287-305 order
       Region 1r5k A 297-305 disorder
SeqProS verified 297-305 Hetero dimer : IID50309Complex
       Region 2llo B 287-305 order
       Region 1r5k A 297-305 disorder
SeqProS verified 297-305 Hetero dimer : IID50309Complex
       Region 2llq B 287-305 order
       Region 1r5k A 297-305 disorder
SeqProS verified 298-304 Hetero dimer : IID00128Complex
       Region 3cbp B 299-302 order
       Region 3cbo B 299-303 order
       Region 3cbm B 298-304 order
       Region 1r5k A 297-305 disorder
Seqphosphorylation
    104-104 Phosphoserine; by CDK2
    106-106 Phosphoserine; by CDK2
    118-118 Phosphoserine
    167-167 Phosphoserine; by CK2
    537-537 Phosphotyrosine; by Tyr-kinases
 
Prediction
NeProc
Disorder 1-181,248-312,549-595
Order 182-247,313-548
ProS 40-82,108-113,248-268,581-595
AlphaFold
Disorder 1-180,216-216,254-304,457-471,549-595
Order 181-215,217-253,305-456,472-548
Pfam Hmmer
PF02159 1-181 4.4e-137
PF00105 183-258 4.6e-51
PF00104 351-543 3.4e-51
SEG 58-70 ,102-119 ,249-264 ,495-511
Function
Function in SwissProt
Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE-independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial association with multiprotein coactivator complexes through LXXLL motifs of their respective components. Mutual transrepression occurs between the estrogen receptor (ER) and NF-kappa-B in a cell-type specific manner. Decreases NF-kappa-B DNA-binding activity and inhibits NF-kappa-B-mediated transcription from the IL6 promoter and displace RELA/p65 and associated coregulators from the promoter. Recruited to the NF-kappa-B response element of the CCL2 and IL8 promoters and can displace CREBBP. Present with NF-kappa-B components RELA/p65 and NFKB1/p50 on ERE sequences. Can also act synergistically with NF-kappa-B to activate transcription involving respective recruitment adjacent response elements; the function involves CREBBP. Can activate the transcriptional activity of TFF1. Also mediates membrane-initiated estrogen signaling involving various kinase cascades. Essential for MTA1-mediated transcriptional regulation of BRCA1 and BCAS3 (PubMed:17922032).
Isoform 3
Involved in activation of NOS3 and endothelial nitric oxide production (PubMed:21937726). Isoforms lacking one or several functional domains are thought to modulate transcriptional activity by competitive ligand or DNA binding and/or heterodimerization with the full-length receptor (PubMed:10970861). Binds to ERE and inhibits isoform 1 (PubMed:10970861).
Biological Process
Diagram with PDB data
ESR1/SMYD2Structural Basis of Estrogen Receptor Alpha Methylation Mediated by Histone Methyltransferase SmyD2
ESR1/ESR1/calm1Solution NMR-derived structure of calmodulin bound with ER alpha peptides
ESR1/SETD7SET7/9-ER-AdoHcy complex
ESR1/SFN14-3-3 protein interaction with Estrogen Receptor Alpha provides a novel drug target interface
See also
Diagram with PDB data
Ncoa1/ESR1Crystal structure of ERa LBD in complex with RU100132
NCOA1/RARACrystal structure of RARalpha ligand binding domain in complex with an agonist ligand (Am580) and a coactivator fragment