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IID00025
 UniprotP14921
ProteinProtein C-ets-1
GeneETS1
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
441
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 276-441 Homo dimer :
 Evidence X-RAY 3wu0 B Reference
       Region 3wu0 B 276-300 disorder
       Region 3wu0 B 301-436 order
       Region 3wu0 B 437-441 disorder
 Evidence X-RAY 3wu0 A Reference
       Region 3wu0 A 276-300 disorder
       Region 3wu0 A 301-440 order
       Region 3wu0 A 441-441 disorder
 Evidence X-RAY 3wtz B Reference
       Region 3wtz B 276-300 disorder
       Region 3wtz B 301-436 order
       Region 3wtz B 437-441 disorder
 Evidence X-RAY 3wtz A Reference
       Region 3wtz A 276-300 disorder
       Region 3wtz A 301-310 order
       Region 3wtz A 311-315 disorder
       Region 3wtz A 316-440 order
       Region 3wtz A 441-441 disorder
 Evidence X-RAY 3ri4 D Reference
       Region 3ri4 D 280-301 disorder
       Region 3ri4 D 302-437 order
       Region 3ri4 D 438-441 disorder
 Evidence X-RAY 3ri4 A Reference
       Region 3ri4 A 280-301 disorder
       Region 3ri4 A 302-437 order
       Region 3ri4 A 438-441 disorder
 Evidence X-RAY 2nny B Reference
       Region 2nny B 280-307 disorder
       Region 2nny B 308-436 order
       Region 2nny B 437-441 disorder
 Evidence X-RAY 2nny A Reference
       Region 2nny A 280-307 disorder
       Region 2nny A 308-436 order
       Region 2nny A 437-441 disorder
 Evidence X-RAY 3mfk B Reference
       Region 3mfk B 280-301 disorder
       Region 3mfk B 302-437 order
       Region 3mfk B 438-441 disorder
 Evidence X-RAY 3mfk A Reference
       Region 3mfk A 280-301 disorder
       Region 3mfk A 302-439 order
       Region 3mfk A 440-441 disorder
 Evidence X-RAY 1gvj B Reference
       Region 1gvj B 297-441 order
 Evidence X-RAY 1gvj A Reference
       Region 1gvj A 297-436 order
       Region 1gvj A 437-441 disorder
Seq 276-441 Hetero trimer :
 Evidence X-RAY 3wty H Reference
       Region 3wty H 276-332 disorder
       Region 3wty H 333-433 order
       Region 3wty H 434-441 disorder
 Evidence X-RAY 3wty C Reference
       Region 3wty C 276-318 disorder
       Region 3wty C 319-436 order
       Region 3wty C 437-441 disorder
 Evidence X-RAY 3wtx H Reference
       Region 3wtx H 276-333 disorder
       Region 3wtx H 334-433 order
       Region 3wtx H 434-441 disorder
 Evidence X-RAY 3wtx C Reference
       Region 3wtx C 276-333 disorder
       Region 3wtx C 334-436 order
       Region 3wtx C 437-441 disorder
 Evidence X-RAY 3wtw H Reference
       Region 3wtw H 276-332 disorder
       Region 3wtw H 333-433 order
       Region 3wtw H 434-441 disorder
 Evidence X-RAY 3wtw C Reference
       Region 3wtw C 276-318 disorder
       Region 3wtw C 319-436 order
       Region 3wtw C 437-441 disorder
 Evidence X-RAY 3wtv H Reference
       Region 3wtv H 276-332 disorder
       Region 3wtv H 333-433 order
       Region 3wtv H 434-441 disorder
 Evidence X-RAY 3wtv C Reference
       Region 3wtv C 276-318 disorder
       Region 3wtv C 319-436 order
       Region 3wtv C 437-441 disorder
 Evidence X-RAY 3wtu H Reference
       Region 3wtu H 276-332 disorder
       Region 3wtu H 333-433 order
       Region 3wtu H 434-441 disorder
 Evidence X-RAY 3wtu C Reference
       Region 3wtu C 276-318 disorder
       Region 3wtu C 319-436 order
       Region 3wtu C 437-441 disorder
 Evidence X-RAY 3wtt H Reference
       Region 3wtt H 276-332 disorder
       Region 3wtt H 333-425 order
       Region 3wtt H 426-441 disorder
 Evidence X-RAY 3wtt C Reference
       Region 3wtt C 276-318 disorder
       Region 3wtt C 319-436 order
       Region 3wtt C 437-441 disorder
 Evidence X-RAY 3wts H Reference
       Region 3wts H 276-332 disorder
       Region 3wts H 333-433 order
       Region 3wts H 434-441 disorder
 Evidence X-RAY 3wts C Reference
       Region 3wts C 276-318 disorder
       Region 3wts C 319-436 order
       Region 3wts C 437-441 disorder
Seq 296-441 Hetero dimer : Q03347
 Evidence X-RAY 4l18 F Reference
       Region 4l18 F 296-331 disorder
       Region 4l18 F 332-437 order
       Region 4l18 F 438-441 disorder
 Evidence X-RAY 4l18 B Reference
       Region 4l18 B 296-332 disorder
       Region 4l18 B 333-439 order
       Region 4l18 B 440-441 disorder
 Evidence X-RAY 4l0z B Reference
       Region 4l0z B 296-331 disorder
       Region 4l0z B 332-432 order
       Region 4l0z B 433-441 disorder
Seq 296-441 Hetero dimer :
 Evidence X-RAY 3wu1 B Reference
       Region 3wu1 B 333-437 order
       Region 3wu1 B 438-441 disorder
 Evidence X-RAY 4l0y B Reference
       Region 4l0y B 296-333 disorder
       Region 4l0y B 334-437 order
       Region 4l0y B 438-441 disorder
Seq 320-415 Monomer :
 Evidence NMR 2stw A Reference
       Region 2stw A 320-415 order
 Evidence NMR 2stt A Reference
       Region 2stt A 320-415 order
       Region 2stt A 331-333 high_rmsd
Seq 331-440 Hetero dimer :
 Evidence X-RAY 4lg0 B Reference
       Region 4lg0 B 331-332 disorder
       Region 4lg0 B 333-438 order
       Region 4lg0 B 439-440 disorder
Seqphosphorylation
    223-223 Phosphotyrosine
    38-38 Phosphothreonine; by MAPK
    251-251 Phosphoserine
    265-265 Phosphothreonine
    254-254 Phosphoserine
    270-270 Phosphoserine
    267-267 Phosphoserine
    282-282 Phosphoserine
    285-285 Phosphoserine
Seqacetylation
    15-15 N6-acetyllysine; alternate
    8-8 N6-acetyllysine; alternate
    305-305 N6-acetyllysine
 
Prediction
NeProc
Disorder 1-42,140-332,439-441
Order 43-139,333-438
ProS 1-25,31-42,140-202,209-292,305-310,316-332,439-441
AlphaFold
Disorder 1-48,136-301,310-317,439-441
Order 49-135,302-309,318-438
Pfam Hmmer
PF02198 53-136 2.1e-48
PF00178 334-417 3.3e-64
SEG 266-278
Function
Function in SwissProt
Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion.