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IID00062
 UniprotP68431
ProteinHistone H3.1
GeneH3C1
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
136
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-16 Hetero dimer : IID00377Complex
 Evidence X-RAY 2co0 D Reference
       Region 2co0 D 2-6 order
       Region 2co0 D 7-16 disorder
 Evidence X-RAY 2co0 B Reference
       Region 2co0 B 2-6 order
       Region 2co0 B 7-16 disorder
 Evidence X-RAY 4a7j B Reference
       Region 4a7j B 1-1 disorder
       Region 4a7j B 2-7 order
       Region 4a7j B 8-16 disorder
Seq 1-136 Hetero tetradecamer : IID00016Complex,IID00058Complex
 Evidence X-RAY 5gse O Reference
       Region 5gse O 1-39 disorder
       Region 5gse O 40-135 order
       Region 5gse O 136-136 disorder
 Evidence X-RAY 5gse K Reference
       Region 5gse K 1-47 disorder
       Region 5gse K 48-135 order
       Region 5gse K 136-136 disorder
 Evidence X-RAY 5gse E Reference
       Region 5gse E 1-38 disorder
       Region 5gse E 39-135 order
       Region 5gse E 136-136 disorder
 Evidence X-RAY 5gse A Reference
       Region 5gse A 1-39 disorder
       Region 5gse A 40-135 order
       Region 5gse A 136-136 disorder
Seq 1-136 Hetero octamer : IID00016Complex,IID00058Complex
 Evidence X-RAY 4ym5 E Reference
       Region 4ym5 E 1-38 disorder
       Region 4ym5 E 39-135 order
       Region 4ym5 E 136-136 disorder
 Evidence X-RAY 4ym5 A Reference
       Region 4ym5 A 1-38 disorder
       Region 4ym5 A 39-136 order
 Evidence X-RAY 3w97 E Reference
       Region 3w97 E 1-37 disorder
       Region 3w97 E 38-136 order
 Evidence X-RAY 3w97 A Reference
       Region 3w97 A 1-38 disorder
       Region 3w97 A 39-135 order
       Region 3w97 A 136-136 disorder
 Evidence X-RAY 5jrg E Reference
       Region 5jrg E 1-37 disorder
       Region 5jrg E 38-136 order
 Evidence X-RAY 5jrg A Reference
       Region 5jrg A 1-38 disorder
       Region 5jrg A 39-135 order
       Region 5jrg A 136-136 disorder
 Evidence X-RAY 5cpk E Reference
       Region 5cpk E 1-38 disorder
       Region 5cpk E 39-136 order
 Evidence X-RAY 5cpk A Reference
       Region 5cpk A 1-38 disorder
       Region 5cpk A 39-135 order
       Region 5cpk A 136-136 disorder
 Evidence X-RAY 5cpi E Reference
       Region 5cpi E 1-38 disorder
       Region 5cpi E 39-136 order
 Evidence X-RAY 5cpi A Reference
       Region 5cpi A 1-38 disorder
       Region 5cpi A 39-135 order
       Region 5cpi A 136-136 disorder
 Evidence X-RAY 5b2j E Reference
       Region 5b2j E 1-37 disorder
       Region 5b2j E 38-136 order
 Evidence X-RAY 5b2j A Reference
       Region 5b2j A 1-37 disorder
       Region 5b2j A 38-136 order
 Evidence X-RAY 5b2i E Reference
       Region 5b2i E 1-37 disorder
       Region 5b2i E 38-136 order
 Evidence X-RAY 5b2i A Reference
       Region 5b2i A 1-37 disorder
       Region 5b2i A 38-136 order
 Evidence X-RAY 5b24 E Reference
       Region 5b24 E 1-37 disorder
       Region 5b24 E 38-136 order
 Evidence X-RAY 5b24 A Reference
       Region 5b24 A 1-38 disorder
       Region 5b24 A 39-135 order
       Region 5b24 A 136-136 disorder
 Evidence X-RAY 3azm E Reference
       Region 3azm E 1-37 disorder
       Region 3azm E 38-136 order
 Evidence X-RAY 3azm A Reference
       Region 3azm A 1-38 disorder
       Region 3azm A 39-136 order
 Evidence X-RAY 3azj E Reference
       Region 3azj E 1-37 disorder
       Region 3azj E 38-135 order
       Region 3azj E 136-136 disorder
 Evidence X-RAY 3azj A Reference
       Region 3azj A 1-38 disorder
       Region 3azj A 39-135 order
       Region 3azj A 136-136 disorder
 Evidence X-RAY 3azg E Reference
       Region 3azg E 1-37 disorder
       Region 3azg E 38-136 order
 Evidence X-RAY 3azg A Reference
       Region 3azg A 1-38 disorder
       Region 3azg A 39-135 order
       Region 3azg A 136-136 disorder
 Evidence X-RAY 3ayw E Reference
       Region 3ayw E 1-37 disorder
       Region 3ayw E 38-134 order
       Region 3ayw E 135-136 disorder
 Evidence X-RAY 3ayw A Reference
       Region 3ayw A 1-38 disorder
       Region 3ayw A 39-135 order
       Region 3ayw A 136-136 disorder
 Evidence X-RAY 5avc E Reference
       Region 5avc E 1-37 disorder
       Region 5avc E 38-136 order
 Evidence X-RAY 5avc A Reference
       Region 5avc A 1-37 disorder
       Region 5avc A 38-136 order
 Evidence X-RAY 5avb E Reference
       Region 5avb E 1-37 disorder
       Region 5avb E 38-136 order
 Evidence X-RAY 5avb A Reference
       Region 5avb A 1-37 disorder
       Region 5avb A 38-136 order
 Evidence X-RAY 5av9 E Reference
       Region 5av9 E 1-37 disorder
       Region 5av9 E 38-136 order
 Evidence X-RAY 5av9 A Reference
       Region 5av9 A 1-37 disorder
       Region 5av9 A 38-136 order
 Evidence X-RAY 5av8 E Reference
       Region 5av8 E 1-37 disorder
       Region 5av8 E 38-136 order
 Evidence X-RAY 5av8 A Reference
       Region 5av8 A 1-37 disorder
       Region 5av8 A 38-136 order
 Evidence X-RAY 5av6 E Reference
       Region 5av6 E 1-37 disorder
       Region 5av6 E 38-136 order
 Evidence X-RAY 5av6 A Reference
       Region 5av6 A 1-37 disorder
       Region 5av6 A 38-136 order
 Evidence X-RAY 5av5 E Reference
       Region 5av5 E 1-37 disorder
       Region 5av5 E 38-136 order
 Evidence X-RAY 5av5 A Reference
       Region 5av5 A 1-37 disorder
       Region 5av5 A 38-136 order
 Evidence X-RAY 3afa E Reference
       Region 3afa E 1-37 disorder
       Region 3afa E 38-136 order
 Evidence X-RAY 3afa A Reference
       Region 3afa A 1-38 disorder
       Region 3afa A 39-135 order
       Region 3afa A 136-136 disorder
Seq 1-136 Hetero octamer : IID00058Complex,IID00614Complex
 Evidence X-RAY 3waa E Reference
       Region 3waa E 1-37 disorder
       Region 3waa E 38-136 order
 Evidence X-RAY 3waa A Reference
       Region 3waa A 1-38 disorder
       Region 3waa A 39-135 order
       Region 3waa A 136-136 disorder
Seq 1-136 Hetero octamer : IID00016Complex,IID00058Complex
 Evidence X-RAY 5cpj E Reference
       Region 5cpj E 1-38 disorder
       Region 5cpj E 39-135 order
       Region 5cpj E 136-136 disorder
 Evidence X-RAY 5cpj A Reference
       Region 5cpj A 1-41 disorder
       Region 5cpj A 42-135 order
       Region 5cpj A 136-136 disorder
 Evidence X-RAY 3azn E Reference
       Region 3azn E 1-37 disorder
       Region 3azn E 38-136 order
 Evidence X-RAY 3azn A Reference
       Region 3azn A 1-38 disorder
       Region 3azn A 39-135 order
       Region 3azn A 136-136 disorder
 Evidence X-RAY 3azl E Reference
       Region 3azl E 1-37 disorder
       Region 3azl E 38-136 order
 Evidence X-RAY 3azl A Reference
       Region 3azl A 1-38 disorder
       Region 3azl A 39-135 order
       Region 3azl A 136-136 disorder
 Evidence X-RAY 3azk E Reference
       Region 3azk E 1-37 disorder
       Region 3azk E 38-136 order
 Evidence X-RAY 3azk A Reference
       Region 3azk A 1-38 disorder
       Region 3azk A 39-135 order
       Region 3azk A 136-136 disorder
 Evidence X-RAY 3azi E Reference
       Region 3azi E 1-37 disorder
       Region 3azi E 38-136 order
 Evidence X-RAY 3azi A Reference
       Region 3azi A 1-38 disorder
       Region 3azi A 39-136 order
 Evidence X-RAY 3azh E Reference
       Region 3azh E 1-37 disorder
       Region 3azh E 38-136 order
 Evidence X-RAY 3azh A Reference
       Region 3azh A 1-38 disorder
       Region 3azh A 39-135 order
       Region 3azh A 136-136 disorder
 Evidence X-RAY 3azf E Reference
       Region 3azf E 1-37 disorder
       Region 3azf E 38-136 order
 Evidence X-RAY 3azf A Reference
       Region 3azf A 1-38 disorder
       Region 3azf A 39-135 order
       Region 3azf A 136-136 disorder
 Evidence X-RAY 3aze E Reference
       Region 3aze E 1-37 disorder
       Region 3aze E 38-136 order
 Evidence X-RAY 3aze A Reference
       Region 3aze A 1-38 disorder
       Region 3aze A 39-135 order
       Region 3aze A 136-136 disorder
Seq 1-136 Hetero octamer : IID00016Complex,IID00058Complex
 Evidence X-RAY 4ym6 E Reference
       Region 4ym6 E 1-37 disorder
       Region 4ym6 E 38-136 order
 Evidence X-RAY 4ym6 A Reference
       Region 4ym6 A 1-38 disorder
       Region 4ym6 A 39-135 order
       Region 4ym6 A 136-136 disorder
 Evidence X-RAY 3w99 E Reference
       Region 3w99 E 1-37 disorder
       Region 3w99 E 38-136 order
 Evidence X-RAY 3w99 A Reference
       Region 3w99 A 1-38 disorder
       Region 3w99 A 39-135 order
       Region 3w99 A 136-136 disorder
 Evidence X-RAY 3w98 E Reference
       Region 3w98 E 29-37 disorder
       Region 3w98 E 38-136 order
 Evidence X-RAY 3w98 A Reference
       Region 3w98 A 29-38 disorder
       Region 3w98 A 39-135 order
       Region 3w98 A 136-136 disorder
 Evidence X-RAY 3w96 E Reference
       Region 3w96 E 1-38 disorder
       Region 3w96 E 39-136 order
 Evidence X-RAY 3w96 A Reference
       Region 3w96 A 1-39 disorder
       Region 3w96 A 40-135 order
       Region 3w96 A 136-136 disorder
Seq 1-136 Hetero octamer : IID00016Complex,IID00019Complex,IID00058Complex
 Evidence X-RAY 5b31 E Reference
       Region 5b31 E 1-38 disorder
       Region 5b31 E 39-135 order
       Region 5b31 E 136-136 disorder
 Evidence X-RAY 5b31 A Reference
       Region 5b31 A 1-38 disorder
       Region 5b31 A 39-135 order
       Region 5b31 A 136-136 disorder
Seq 1-136 Hetero tetramer : IID00058Complex,IID00182Complex,IID00715Complex
 Evidence X-RAY 5c3i V Reference
       Region 5c3i V 1-59 disorder
       Region 5c3i V 60-135 order
       Region 5c3i V 136-136 disorder
 Evidence X-RAY 5c3i R Reference
       Region 5c3i R 1-60 disorder
       Region 5c3i R 61-134 order
       Region 5c3i R 135-136 disorder
 Evidence X-RAY 5c3i N Reference
       Region 5c3i N 1-59 disorder
       Region 5c3i N 60-135 order
       Region 5c3i N 136-136 disorder
 Evidence X-RAY 5c3i F Reference
       Region 5c3i F 1-47 disorder
       Region 5c3i F 48-135 order
       Region 5c3i F 136-136 disorder
 Evidence X-RAY 5c3i J Reference
       Region 5c3i J 1-51 disorder
       Region 5c3i J 52-135 order
       Region 5c3i J 136-136 disorder
Seq 1-136 Hetero nonamer : IID00016Complex,IID00058Complex
 Evidence X-RAY 5gtc E Reference
       Region 5gtc E 1-38 disorder
       Region 5gtc E 39-136 order
 Evidence X-RAY 5gtc A Reference
       Region 5gtc A 1-38 disorder
       Region 5gtc A 39-135 order
       Region 5gtc A 136-136 disorder
Seq 1-136 Hetero octamer : IID00019Complex,IID00058Complex
 Evidence X-RAY 3wa9 E Reference
       Region 3wa9 E 1-37 disorder
       Region 3wa9 E 38-135 order
       Region 3wa9 E 136-136 disorder
 Evidence X-RAY 3wa9 A Reference
       Region 3wa9 A 1-38 disorder
       Region 3wa9 A 39-135 order
       Region 3wa9 A 136-136 disorder
Seq 1-136 Hetero octamer : IID00016Complex,IID00058Complex
 Evidence X-RAY 3wkj E Reference
       Region 3wkj E 1-38 disorder
       Region 3wkj E 39-136 order
 Evidence X-RAY 3wkj A Reference
       Region 3wkj A 1-38 disorder
       Region 3wkj A 39-135 order
       Region 3wkj A 136-136 disorder
Seq 1-136 Hetero octamer : IID00016Complex,IID00058Complex
 Evidence X-RAY 2cv5 E Reference
       Region 2cv5 E 1-37 disorder
       Region 2cv5 E 38-136 order
 Evidence X-RAY 2cv5 A Reference
       Region 2cv5 A 1-38 disorder
       Region 2cv5 A 39-135 order
       Region 2cv5 A 136-136 disorder
Seq 1-136 Hetero tetramer : IID00058Complex,IID00182Complex,IID00715Complex
 Evidence X-RAY 5c3i B Reference
       Region 5c3i B 1-48 disorder
       Region 5c3i B 49-135 order
       Region 5c3i B 136-136 disorder
Seq 2-6 Hetero dimer : IID50141Complex,IID90020Complex
 Evidence X-RAY 3mp1 P Reference
       Region 3mp1 P 2-6 order
Seq 2-7 Hetero dimer : Q56A73
 Evidence X-RAY 4uy4 C Reference
       Region 4uy4 C 2-7 order
 Evidence X-RAY 4uy4 D Reference
       Region 4uy4 D 2-7 order
Seq 2-7 Hetero dimer : IID00186Complex
 Evidence X-RAY 4a0n C Reference
       Region 4a0n C 2-5 order
       Region 4a0n C 6-7 disorder
 Evidence X-RAY 4a0j D Reference
       Region 4a0j D 2-6 order
       Region 4a0j D 7-7 disorder
 Evidence X-RAY 4a0j C Reference
       Region 4a0j C 2-7 order
Seq 2-8 Hetero dimer : IID00336Complex
 Evidence X-RAY 4qbs P Reference
       Region 4qbs P 2-8 order
 Evidence X-RAY 4qbr E Reference
       Region 4qbr E 2-8 order
 Evidence X-RAY 4qbr P Reference
       Region 4qbr P 2-8 order
Seq 2-9 Hetero trimer : IID00336Complex
 Evidence X-RAY 4qbq P Reference
       Region 4qbq P 2-9 order
Seq 2-9 Hetero tetramer : IID00327Complex
 Evidence X-RAY 3zvy C Reference
       Region 3zvy C 2-6 order
       Region 3zvy C 7-9 disorder
 Evidence X-RAY 3zvy D Reference
       Region 3zvy D 2-6 order
       Region 3zvy D 7-9 disorder
Seq 2-10 Hetero dimer : IID00327Complex
 Evidence X-RAY 3sow D Reference
       Region 3sow D 2-7 order
       Region 3sow D 8-10 disorder
 Evidence X-RAY 3sow C Reference
       Region 3sow C 2-7 order
       Region 3sow C 8-10 disorder
 Evidence X-RAY 3sou E Reference
       Region 3sou E 2-9 order
       Region 3sou E 10-10 disorder
 Evidence X-RAY 3sou D Reference
       Region 3sou D 2-9 order
       Region 3sou D 10-10 disorder
Seq 2-10 Hetero dimer : IID00379Complex
 Evidence X-RAY 3lqj T Reference
       Region 3lqj T 2-7 order
       Region 3lqj T 8-10 disorder
 Evidence X-RAY 3lqj Q Reference
       Region 3lqj Q 2-7 order
       Region 3lqj Q 8-10 disorder
 Evidence X-RAY 3lqi T Reference
       Region 3lqi T 2-10 order
 Evidence X-RAY 3lqi S Reference
       Region 3lqi S 2-8 order
       Region 3lqi S 9-10 disorder
 Evidence X-RAY 3lqi R Reference
       Region 3lqi R 2-7 order
       Region 3lqi R 8-10 disorder
Seq 2-10 Hetero dimer : IID00071Complex
 Evidence X-RAY 2ri7 P Reference
       Region 2ri7 P 2-7 order
       Region 2ri7 P 8-10 disorder
Seq 2-10 Hetero trimer : Q96EQ9
 Evidence X-RAY 4c1q C Reference
       Region 4c1q C 2-8 order
       Region 4c1q C 9-10 disorder
Seq 2-10 Hetero dimer : IID00128Complex
 Evidence X-RAY 1o9s L Reference
       Region 1o9s L 2-7 order
       Region 1o9s L 8-10 disorder
 Evidence X-RAY 1o9s K Reference
       Region 1o9s K 2-10 order
Seq 2-11 Hetero dimer : P29375
 Evidence X-RAY 5c11 B Reference
       Region 5c11 B 2-8 order
       Region 5c11 B 9-11 disorder
Seq 2-11 Hetero tetramer : Q5VWG9
 Evidence X-RAY 5c13 H Reference
       Region 5c13 H 2-7 order
       Region 5c13 H 8-11 disorder
 Evidence X-RAY 5c13 D Reference
       Region 5c13 D 2-7 order
       Region 5c13 D 8-11 disorder
 Evidence X-RAY 5c13 P Reference
       Region 5c13 P 2-7 order
       Region 5c13 P 8-11 disorder
 Evidence X-RAY 5c13 F Reference
       Region 5c13 F 2-7 order
       Region 5c13 F 8-11 disorder
Seq 2-11 Hetero dimer : Q9UNL4
 Evidence X-RAY 2vnf D Reference
       Region 2vnf D 2-11 order
 Evidence X-RAY 2vnf B Reference
       Region 2vnf B 2-7 order
       Region 2vnf B 8-11 disorder
Seq 2-11 Hetero dimer : IID00289Complex
 Evidence X-RAY 3o37 H Reference
       Region 3o37 H 2-11 order
 Evidence X-RAY 3o37 G Reference
       Region 3o37 G 2-11 order
 Evidence X-RAY 3o37 F Reference
       Region 3o37 F 2-11 order
 Evidence X-RAY 3o37 E Reference
       Region 3o37 E 2-11 order
Seq 2-13 Hetero dimer : P21784
 Evidence X-RAY 2v89 D Reference
       Region 2v89 D 2-10 order
 Evidence X-RAY 2v89 E Reference
       Region 2v89 E 2-10 order
 Evidence X-RAY 2v85 E Reference
       Region 2v85 E 2-10 order
       Region 2v85 E 11-13 disorder
 Evidence X-RAY 2v85 D Reference
       Region 2v85 D 2-13 order
Seq 2-13 Hetero dimer : Q9BTC0
 Evidence X-RAY 4l7x U Reference
       Region 4l7x U 2-8 order
       Region 4l7x U 9-13 disorder
Seq 2-13 Hetero trimer :
 Evidence X-RAY 4yhz P Reference
       Region 4yhz P 2-10 order
       Region 4yhz P 11-13 disorder
Seq 2-13 Hetero trimer : O75151
 Evidence X-RAY 3kqi B Reference
       Region 3kqi B 2-7 order
       Region 3kqi B 8-13 disorder
Seq 2-14 Hetero dimer : IID00322Complex
 Evidence NMR 2l75 B Reference
       Region 2l75 B 2-12 order
       Region 2l75 B 13-14 disorder
Seq 2-16 Hetero dimer : Q86UU0,Q9BRQ0
 Evidence X-RAY 4up0 F Reference
       Region 4up0 F 2-7 order
       Region 4up0 F 8-16 disorder
Seq 2-16 Hetero dimer : P23497
 Evidence X-RAY 5fb1 C Reference
       Region 5fb1 C 2-9 order
       Region 5fb1 C 10-16 disorder
Seq 2-16 Hetero tetramer : IID00003Complex
 Evidence X-RAY 2b2v D Reference
       Region 2b2v D 2-7 order
       Region 2b2v D 8-16 disorder
 Evidence X-RAY 2b2u D Reference
       Region 2b2u D 2-6 order
       Region 2b2u D 7-16 disorder
Seq 2-16 Hetero dimer : IID50064Complex
 Evidence X-RAY 1q3l P Reference
       Region 1q3l P 2-5 disorder
       Region 1q3l P 6-11 order
       Region 1q3l P 12-16 disorder
Seq 2-16 Hetero tetramer : IID00186Complex
 Evidence X-RAY 3uik Q Reference
       Region 3uik Q 2-5 order
       Region 3uik Q 6-11 disorder
 Evidence X-RAY 3uik P Reference
       Region 3uik P 2-5 order
       Region 3uik P 6-11 disorder
 Evidence X-RAY 3uii Q Reference
       Region 3uii Q 2-5 order
       Region 3uii Q 6-11 disorder
 Evidence X-RAY 3uii P Reference
       Region 3uii P 2-5 order
       Region 3uii P 6-11 disorder
 Evidence X-RAY 3uig Q Reference
       Region 3uig Q 2-6 order
       Region 3uig Q 7-16 disorder
 Evidence X-RAY 3uig P Reference
       Region 3uig P 2-6 order
       Region 3uig P 7-16 disorder
 Evidence X-RAY 3uef D Reference
       Region 3uef D 2-5 order
       Region 3uef D 6-13 disorder
 Evidence X-RAY 3uef B Reference
       Region 3uef B 2-6 order
       Region 3uef B 7-13 disorder
 Evidence X-RAY 3uee D Reference
       Region 3uee D 2-6 order
       Region 3uee D 7-13 disorder
 Evidence X-RAY 3uee B Reference
       Region 3uee B 2-6 order
       Region 3uee B 7-13 disorder
Seq 2-16 Hetero trimer : IID00500Complex
 Evidence X-RAY 3b95 P Reference
       Region 3b95 P 2-4 order
       Region 3b95 P 5-7 disorder
       Region 3b95 P 8-14 order
       Region 3b95 P 15-16 disorder
Seq 2-16 Hetero dimer : IID00303Complex
 Evidence NMR 2lbm C Reference
       Region 2lbm C 2-16 order
Seq 2-16 Hetero dimer : P23497
 Evidence X-RAY 5fb0 F Reference
       Region 5fb0 F 2-11 order
       Region 5fb0 F 12-16 disorder
 Evidence X-RAY 5fb0 D Reference
       Region 5fb0 D 2-11 order
       Region 5fb0 D 12-16 disorder
Seq 2-16 Hetero tetramer : Q504Y3
 Evidence X-RAY 4z0r D Reference
       Region 4z0r D 2-11 order
       Region 4z0r D 12-16 disorder
Seq 2-17 Hetero decamer :
 Evidence X-RAY 4yhp Q Reference
       Region 4yhp Q 2-12 order
       Region 4yhp Q 13-17 disorder
 Evidence X-RAY 4yhp P Reference
       Region 4yhp P 2-12 order
       Region 4yhp P 13-17 disorder
Seq 2-19 Hetero trimer : IID00255Complex
 Evidence X-RAY 2vpg R Reference
       Region 2vpg R 2-8 order
       Region 2vpg R 9-19 disorder
 Evidence X-RAY 2vpg P Reference
       Region 2vpg P 2-8 order
       Region 2vpg P 9-19 disorder
Seq 2-20 Hetero tetramer : IID00003Complex
 Evidence X-RAY 2b2w D Reference
       Region 2b2w D 2-6 order
       Region 2b2w D 7-20 disorder
 Evidence X-RAY 2b2t D Reference
       Region 2b2t D 2-6 order
       Region 2b2t D 7-20 disorder
Seq 2-21 Monomer : IID00336Complex
 Evidence X-RAY 3a1b A Reference
       Region 3a1b A 2-10 order
       Region 3a1b A 11-17 disorder
       Region 3a1b A 18-21 order
Seq 2-21 Hetero dimer : IID00487Complex
 Evidence X-RAY 4fwf E Reference
       Region 4fwf E 2-14 order
       Region 4fwf E 15-21 disorder
Seq 2-21 Hetero trimer : IID00009Complex
 Evidence X-RAY 2x0l C Reference
       Region 2x0l C 6-17 order
 Evidence X-RAY 5h6r C Reference
       Region 5h6r C 2-15 order
       Region 5h6r C 16-21 disorder
 Evidence X-RAY 5h6q C Reference
       Region 5h6q C 2-16 order
       Region 5h6q C 17-21 disorder
Seq 2-21 Hetero dimer : IID00418Complex
 Evidence NMR 2kwk B Reference
       Region 2kwk B 2-11 order
       Region 2kwk B 12-21 disorder
 Evidence NMR 2kwj B Reference
       Region 2kwj B 2-21 order
       Region 2kwj B 20-21 high_rmsd
Seq 2-22 Hetero trimer : IID00009Complex
 Evidence X-RAY 2uxn E Reference
       Region 2uxn E 2-8 order
       Region 2uxn E 9-22 disorder
Seq 2-22 Hetero dimer : IID00489Complex
 Evidence X-RAY 3v43 Q Reference
       Region 3v43 Q 2-8 order
       Region 3v43 Q 9-19 disorder
 Evidence X-RAY 4llb D Reference
       Region 4llb D 2-16 order
       Region 4llb D 17-22 disorder
 Evidence X-RAY 4llb C Reference
       Region 4llb C 2-16 order
       Region 4llb C 17-22 disorder
 Evidence X-RAY 4lka B Reference
       Region 4lka B 2-13 order
       Region 4lka B 14-22 disorder
 Evidence X-RAY 4lk9 B Reference
       Region 4lk9 B 2-14 order
       Region 4lk9 B 15-22 disorder
Seq 2-29 Hetero dimer : IID00505Complex
 Evidence X-RAY 3u5p P Reference
       Region 3u5p P 2-13 order
       Region 3u5p P 14-15 disorder
       Region 3u5p P 16-19 order
       Region 3u5p P 20-29 disorder
 Evidence X-RAY 3u5p O Reference
       Region 3u5p O 2-19 order
       Region 3u5p O 20-29 disorder
 Evidence X-RAY 3u5p N Reference
       Region 3u5p N 2-13 order
       Region 3u5p N 14-15 disorder
       Region 3u5p N 16-19 order
       Region 3u5p N 20-29 disorder
 Evidence X-RAY 3u5p M Reference
       Region 3u5p M 2-20 order
       Region 3u5p M 21-29 disorder
 Evidence X-RAY 3u5p L Reference
       Region 3u5p L 2-19 order
       Region 3u5p L 20-29 disorder
 Evidence X-RAY 3u5p K Reference
       Region 3u5p K 2-13 order
       Region 3u5p K 14-15 disorder
       Region 3u5p K 16-19 order
       Region 3u5p K 20-29 disorder
 Evidence X-RAY 3u5p J Reference
       Region 3u5p J 2-13 order
       Region 3u5p J 14-15 disorder
       Region 3u5p J 16-19 order
       Region 3u5p J 20-29 disorder
 Evidence X-RAY 3u5p I Reference
       Region 3u5p I 2-19 order
       Region 3u5p I 20-29 disorder
 Evidence X-RAY 3u5o P Reference
       Region 3u5o P 2-21 order
       Region 3u5o P 22-23 disorder
 Evidence X-RAY 3u5o O Reference
       Region 3u5o O 2-21 order
       Region 3u5o O 22-23 disorder
 Evidence X-RAY 3u5o N Reference
       Region 3u5o N 2-21 order
       Region 3u5o N 22-23 disorder
 Evidence X-RAY 3u5o M Reference
       Region 3u5o M 2-21 order
       Region 3u5o M 22-23 disorder
 Evidence X-RAY 3u5o L Reference
       Region 3u5o L 2-21 order
       Region 3u5o L 22-23 disorder
 Evidence X-RAY 3u5o K Reference
       Region 3u5o K 2-21 order
       Region 3u5o K 22-23 disorder
 Evidence X-RAY 3u5o J Reference
       Region 3u5o J 2-21 order
       Region 3u5o J 22-23 disorder
 Evidence X-RAY 3u5o I Reference
       Region 3u5o I 2-21 order
       Region 3u5o I 22-23 disorder
 Evidence X-RAY 3u5n D Reference
       Region 3u5n D 2-21 order
 Evidence X-RAY 3u5n C Reference
       Region 3u5n C 2-11 order
       Region 3u5n C 12-21 disorder
Seq 2-136 Hetero octamer : IID00016Complex,IID00058Complex
 Evidence X-RAY 3x1s E Reference
       Region 3x1s E 2-38 disorder
       Region 3x1s E 39-136 order
 Evidence X-RAY 3x1s A Reference
       Region 3x1s A 2-39 disorder
       Region 3x1s A 40-135 order
       Region 3x1s A 136-136 disorder
Seq 2-136 Hetero octamer : IID00058Complex,Q96QV6
 Evidence X-RAY 5gsu E Reference
       Region 5gsu E 2-37 disorder
       Region 5gsu E 38-136 order
 Evidence X-RAY 5gsu A Reference
       Region 5gsu A 2-37 disorder
       Region 5gsu A 38-136 order
Seq 2-136 Hetero octamer : IID00058Complex,Q96QV6
 Evidence X-RAY 5gt0 E Reference
       Region 5gt0 E 2-37 disorder
       Region 5gt0 E 38-136 order
 Evidence X-RAY 5gt0 A Reference
       Region 5gt0 A 2-37 disorder
       Region 5gt0 A 38-136 order
Seq 2-136 Hetero octamer : IID00058Complex,P20671
 Evidence X-RAY 5gt3 E Reference
       Region 5gt3 E 2-37 disorder
       Region 5gt3 E 38-136 order
 Evidence X-RAY 5gt3 A Reference
       Region 5gt3 A 2-38 disorder
       Region 5gt3 A 39-136 order
Seq 2-136 Hetero octamer : IID00016Complex,IID00058Complex
 Evidence X-RAY 3x1v E Reference
       Region 3x1v E 2-37 disorder
       Region 3x1v E 38-136 order
 Evidence X-RAY 3x1v A Reference
       Region 3x1v A 2-38 disorder
       Region 3x1v A 39-136 order
Seq 2-136 Hetero octamer : IID00058Complex,Q8CGP4
 Evidence X-RAY 3x1u E Reference
       Region 3x1u E 2-37 disorder
       Region 3x1u E 38-136 order
 Evidence X-RAY 3x1u A Reference
       Region 3x1u A 2-38 disorder
       Region 3x1u A 39-136 order
Seq 2-136 Hetero octamer : IID00058Complex,Q8CGP4
 Evidence X-RAY 3x1t E Reference
       Region 3x1t E 2-38 disorder
       Region 3x1t E 39-136 order
 Evidence X-RAY 3x1t A Reference
       Region 3x1t A 2-38 disorder
       Region 3x1t A 39-136 order
Seq 4-9 Hetero dimer : IID00552Complex
 Evidence X-RAY 5hjb B Reference
       Region 5hjb B 4-9 order
Seq 4-12 Hetero tetramer : IID00500Complex
 Evidence X-RAY 4i51 D Reference
       Region 4i51 D 4-5 disorder
       Region 4i51 D 6-12 order
 Evidence X-RAY 4i51 C Reference
       Region 4i51 C 4-12 order
Seq 4-14 Hetero tetramer : IID00250Complex
 Evidence X-RAY 5jj0 G Reference
       Region 5jj0 G 4-12 order
       Region 5jj0 G 13-14 disorder
 Evidence X-RAY 5jj0 F Reference
       Region 5jj0 F 4-4 disorder
       Region 5jj0 F 5-12 order
       Region 5jj0 F 13-14 disorder
 Evidence X-RAY 5jiy G Reference
       Region 5jiy G 4-12 order
       Region 5jiy G 13-14 disorder
 Evidence X-RAY 5jiy F Reference
       Region 5jiy F 4-4 disorder
       Region 5jiy F 5-12 order
       Region 5jiy F 13-14 disorder
 Evidence X-RAY 5jin G Reference
       Region 5jin G 4-12 order
       Region 5jin G 13-14 disorder
 Evidence X-RAY 5jin F Reference
       Region 5jin F 4-4 disorder
       Region 5jin F 5-12 order
       Region 5jin F 13-14 disorder
 Evidence X-RAY 5jhn G Reference
       Region 5jhn G 4-12 order
       Region 5jhn G 13-14 disorder
 Evidence X-RAY 5jhn F Reference
       Region 5jhn F 4-4 disorder
       Region 5jhn F 5-12 order
       Region 5jhn F 13-14 disorder
Seq 5-14 Hetero dimer : Q8IE47
 Evidence X-RAY 3u3d B Reference
       Region 3u3d B 5-6 disorder
       Region 3u3d B 7-13 order
       Region 3u3d B 14-14 disorder
 Evidence X-RAY 3u31 B Reference
       Region 3u31 B 5-6 disorder
       Region 3u31 B 7-12 order
       Region 3u31 B 13-14 disorder
Seq 5-14 Hetero dimer : IID00486Complex
 Evidence X-RAY 3zg6 F Reference
       Region 3zg6 F 5-14 order
Seq 5-15 Hetero tetramer : Q7JXA8
 Evidence X-RAY 4u68 F Reference
       Region 4u68 F 5-11 order
       Region 4u68 F 12-15 disorder
 Evidence X-RAY 4u68 E Reference
       Region 4u68 E 5-11 order
       Region 4u68 E 12-15 disorder
 Evidence X-RAY 4u68 D Reference
       Region 4u68 D 5-11 order
       Region 4u68 D 12-15 disorder
Seq 5-16 Hetero dimer : IID00502Complex
 Evidence X-RAY 3riy C Reference
       Region 3riy C 5-6 disorder
       Region 3riy C 7-13 order
       Region 3riy C 14-16 disorder
 Evidence X-RAY 3riy D Reference
       Region 3riy D 5-6 disorder
       Region 3riy D 7-14 order
       Region 3riy D 15-16 disorder
 Evidence X-RAY 3rig D Reference
       Region 3rig D 5-6 disorder
       Region 3rig D 7-12 order
       Region 3rig D 13-16 disorder
 Evidence X-RAY 3rig C Reference
       Region 3rig C 5-6 disorder
       Region 3rig C 7-12 order
       Region 3rig C 13-16 disorder
 Evidence X-RAY 4f56 D Reference
       Region 4f56 D 5-6 disorder
       Region 4f56 D 7-13 order
       Region 4f56 D 14-16 disorder
 Evidence X-RAY 4f56 C Reference
       Region 4f56 C 5-6 disorder
       Region 4f56 C 7-13 order
       Region 4f56 C 14-16 disorder
 Evidence X-RAY 4f4u D Reference
       Region 4f4u D 5-6 disorder
       Region 4f4u D 7-13 order
       Region 4f4u D 14-16 disorder
 Evidence X-RAY 4f4u C Reference
       Region 4f4u C 5-6 disorder
       Region 4f4u C 7-13 order
       Region 4f4u C 14-16 disorder
Seq 7-13 Hetero dimer : Q8IXJ6
 Evidence X-RAY 4y6l D Reference
       Region 4y6l D 7-13 order
 Evidence X-RAY 4y6l C Reference
       Region 4y6l C 7-13 order
Seq 7-16 Hetero dimer : IID00481Complex
 Evidence X-RAY 4hon G Reference
       Region 4hon G 7-7 disorder
       Region 4hon G 8-14 order
       Region 4hon G 15-16 disorder
 Evidence X-RAY 4hon F Reference
       Region 4hon F 7-16 order
Seq 8-15 Hetero dimer : O94953
 Evidence X-RAY 4lxl D Reference
       Region 4lxl D 8-15 order
Seq 8-15 Hetero dimer : IID00360Complex
 Evidence X-RAY 3u4s D Reference
       Region 3u4s D 8-13 order
       Region 3u4s D 14-15 disorder
 Evidence X-RAY 3u4s C Reference
       Region 3u4s C 8-15 order
 Evidence X-RAY 2ox0 D Reference
       Region 2ox0 D 8-15 order
 Evidence X-RAY 2ox0 C Reference
       Region 2ox0 C 8-15 order
 Evidence X-RAY 2ot7 D Reference
       Region 2ot7 D 8-15 order
 Evidence X-RAY 2ot7 C Reference
       Region 2ot7 C 8-15 order
 Evidence X-RAY 2oq6 D Reference
       Region 2oq6 D 8-15 order
 Evidence X-RAY 2oq6 C Reference
       Region 2oq6 C 8-15 order
Seq 8-15 Hetero dimer : IID00061Complex
 Evidence X-RAY 2c1n E Reference
       Region 2c1n E 8-15 order
 Evidence X-RAY 2c1n C Reference
       Region 2c1n C 8-15 order
Seq 8-15 Hetero tetramer : IID00061Complex
 Evidence X-RAY 2c1j D Reference
       Region 2c1j D 8-15 order
 Evidence X-RAY 2c1j C Reference
       Region 2c1j C 8-15 order
Seq 10-20 Hetero dimer : IID00374Complex
 Evidence X-RAY 5ffv D Reference
       Region 5ffv D 10-10 disorder
       Region 5ffv D 11-18 order
       Region 5ffv D 19-20 disorder
 Evidence X-RAY 5ffv C Reference
       Region 5ffv C 10-10 disorder
       Region 5ffv C 11-18 order
       Region 5ffv C 19-20 disorder
Seq 12-28 Hetero dimer : IID00094Complex
 Evidence X-RAY 5j3v C Reference
       Region 5j3v C 12-28 order
Seq 12-28 Hetero dimer : IID00094Complex
 Evidence X-RAY 5j3v D Reference
       Region 5j3v D 12-28 order
Seq 13-25 Hetero dimer : IID00552Complex
 Evidence NMR 2ndg B Reference
       Region 2ndg B 13-25 order
 Evidence NMR 2ndf B Reference
       Region 2ndf B 13-25 order
Seq 14-33 Hetero dimer : IID00289Complex
 Evidence X-RAY 3o35 E Reference
       Region 3o35 E 24-25 disorder
       Region 3o35 E 26-30 order
       Region 3o35 E 31-32 disorder
 Evidence X-RAY 3o34 B Reference
       Region 3o34 B 14-22 disorder
       Region 3o34 B 23-33 order
Seq 15-21 Hetero octamer : IID00552Complex
 Evidence X-RAY 5hjd M Reference
       Region 5hjd M 15-21 order
 Evidence X-RAY 5hjd J Reference
       Region 5hjd J 15-15 disorder
       Region 5hjd J 16-21 order
 Evidence X-RAY 5hjd I Reference
       Region 5hjd I 15-15 disorder
       Region 5hjd I 16-20 order
       Region 5hjd I 21-21 disorder
 Evidence X-RAY 5hjd H Reference
       Region 5hjd H 15-15 disorder
       Region 5hjd H 16-20 order
       Region 5hjd H 21-21 disorder
 Evidence X-RAY 5hjd L Reference
       Region 5hjd L 15-21 order
 Evidence X-RAY 5hjd F Reference
       Region 5hjd F 15-15 disorder
       Region 5hjd F 16-20 order
       Region 5hjd F 21-21 disorder
 Evidence X-RAY 5hjd D Reference
       Region 5hjd D 15-21 order
 Evidence X-RAY 5hjd B Reference
       Region 5hjd B 15-21 order
Seq 16-24 Hetero dimer : Q15059
 Evidence X-RAY 5hjc B Reference
       Region 5hjc B 16-24 order
Seq 16-40 Hetero dimer : Q03111
 Evidence X-RAY 5j9s B Reference
       Region 5j9s B 16-24 disorder
       Region 5j9s B 25-30 order
       Region 5j9s B 31-40 disorder
Seq 18-39 Hetero dimer : IID00431Complex
 Evidence X-RAY 3avr B Reference
       Region 3avr B 18-34 order
       Region 3avr B 35-39 disorder
Seq 20-29 Hetero decamer : IID00360Complex
 Evidence X-RAY 5d6y d Reference
       Region 5d6y d 20-20 disorder
       Region 5d6y d 21-27 order
       Region 5d6y d 28-29 disorder
 Evidence X-RAY 5d6y c Reference
       Region 5d6y c 20-20 disorder
       Region 5d6y c 21-27 order
       Region 5d6y c 28-29 disorder
 Evidence X-RAY 5d6y b Reference
       Region 5d6y b 20-28 order
       Region 5d6y b 29-29 disorder
 Evidence X-RAY 5d6y a Reference
       Region 5d6y a 20-28 order
       Region 5d6y a 29-29 disorder
Seq 20-30 Hetero dimer : P55197
 Evidence X-RAY 5dah C Reference
       Region 5dah C 20-20 disorder
       Region 5dah C 21-29 order
       Region 5dah C 30-30 disorder
 Evidence X-RAY 5dah D Reference
       Region 5dah D 20-20 disorder
       Region 5dah D 21-29 order
       Region 5dah D 30-30 disorder
Seq 22-34 Hetero pentamer : IID00727Complex
 Evidence X-RAY 5hyn T Reference
       Region 5hyn T 22-22 disorder
       Region 5hyn T 23-31 order
       Region 5hyn T 32-34 disorder
 Evidence X-RAY 5hyn O Reference
       Region 5hyn O 22-22 disorder
       Region 5hyn O 23-31 order
       Region 5hyn O 32-34 disorder
 Evidence X-RAY 5hyn I Reference
       Region 5hyn I 22-22 disorder
       Region 5hyn I 23-31 order
       Region 5hyn I 32-34 disorder
 Evidence X-RAY 5hyn D Reference
       Region 5hyn D 22-22 disorder
       Region 5hyn D 23-31 order
       Region 5hyn D 32-34 disorder
Seq 22-43 Hetero dimer : Q8R5C8
 Evidence X-RAY 4n4h B Reference
       Region 4n4h B 22-29 disorder
       Region 4n4h B 30-40 order
       Region 4n4h B 41-43 disorder
Seq 23-33 Hetero trimer : G0RYC6,G0S8H7,IID50297Complex
 Evidence X-RAY 5kjh D Reference
       Region 5kjh D 23-23 disorder
       Region 5kjh D 24-31 order
       Region 5kjh D 32-33 disorder
Seq 24-30 Hetero tetramer : Q8VDS3
 Evidence X-RAY 4x3k D Reference
       Region 4x3k D 24-30 order
 Evidence X-RAY 4x3k C Reference
       Region 4x3k C 24-30 order
Seq 24-32 Hetero dimer :
 Evidence X-RAY 3o35 D Reference
       Region 3o35 D 24-32 disorder
Seq 25-32 Hetero dimer : Q9ULM3
 Evidence X-RAY 5iql B Reference
       Region 5iql B 25-32 order
Seq 26-33 Hetero dimer : IID90012Complex
 Evidence X-RAY 3kmt I Reference
       Region 3kmt I 26-33 order
 Evidence X-RAY 3kmt H Reference
       Region 3kmt H 26-33 order
 Evidence X-RAY 3kmt G Reference
       Region 3kmt G 26-33 order
Seq 30-44 Hetero trimer : P59997
 Evidence X-RAY 4tn7 F Reference
       Region 4tn7 F 30-39 order
       Region 4tn7 F 40-44 disorder
 Evidence X-RAY 4tn7 E Reference
       Region 4tn7 E 30-39 order
       Region 4tn7 E 40-44 disorder
Seq 32-42 Hetero dimer : IID00480Complex
 Evidence NMR 4bd3 B Reference
       Region 4bd3 B 32-42 order
Seq 32-42 Hetero dimer : IID00432Complex
 Evidence NMR 2m0o B Reference
       Region 2m0o B 32-42 order
Seq 35-136 Hetero pentamer : IID00058Complex,Q9Y5B9
 Evidence X-RAY 4z2m I Reference
       Region 4z2m I 35-60 disorder
       Region 4z2m I 61-136 order
 Evidence X-RAY 4z2m G Reference
       Region 4z2m G 35-58 disorder
       Region 4z2m G 59-135 order
       Region 4z2m G 136-136 disorder
Seq 45-58 Hetero dimer : IID00092Complex
 Evidence X-RAY 5gh9 B Reference
       Region 5gh9 B 45-52 disorder
       Region 5gh9 B 53-58 order
Seq 74-84 Hetero dimer : Q7Z4V5
 Evidence X-RAY 3qj6 T Reference
       Region 3qj6 T 74-76 disorder
       Region 3qj6 T 77-81 order
       Region 3qj6 T 82-84 disorder
Seq 131-136 Monomer :
 Evidence NMR 1ct6 A Reference
       Region 1ct6 A 131-136 order
 Evidence NMR 1cs9 A Reference
       Region 1cs9 A 131-136 order
SeqProS verified 2-6 Hetero tetramer : IID00003Complex
       Region 2b2w D 2-6 order
       Region 2b2t D 2-6 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-6 Hetero tetramer : IID00186Complex
       Region 3uee B 2-6 order
       Region 3uee D 2-6 order
       Region 3uef B 2-6 order
       Region 3uef D 2-5 order
       Region 3uig P 2-6 order
       Region 3uig Q 2-6 order
       Region 3uik P 2-5 order
       Region 3uik Q 2-5 order
       Region 3uii P 2-5 order
       Region 3uii Q 2-5 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-7 Hetero dimer : IID00377Complex
       Region 4a7j B 2-7 order
       Region 2co0 B 2-6 order
       Region 2co0 D 2-6 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-7 Hetero dimer : IID00186Complex
       Region 4a0n C 2-5 order
       Region 4a0j C 2-7 order
       Region 4a0j D 2-6 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-7 Hetero tetramer : IID00003Complex
       Region 2b2v D 2-7 order
       Region 2b2u D 2-6 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-7 Hetero dimer : IID00071Complex
       Region 2ri7 P 2-7 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-8 Hetero trimer : IID00009Complex
       Region 2uxn E 2-8 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-11 Hetero dimer : IID00289Complex
       Region 3o37 E 2-11 order
       Region 3o37 F 2-11 order
       Region 3o37 G 2-11 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-11 Hetero dimer : Q9UNL4
       Region 2vnf B 2-7 order
       Region 2vnf D 2-11 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-11 Hetero dimer : P23497
       Region 5fb1 C 2-9 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-11 Hetero dimer : P23497
       Region 5fb0 D 2-11 order
       Region 5fb0 F 2-11 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-12 Hetero dimer : IID00322Complex
       Region 2l75 B 2-12 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-14 Hetero dimer : IID00487Complex
       Region 4fwf E 2-14 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-4,8-14 Hetero trimer : IID00500Complex
       Region 3b95 P 2-4 order
       Region 3b95 P 8-14 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-16 Hetero dimer : IID00379Complex
       Region 3lqi R 2-7 order
       Region 3lqi S 2-8 order
       Region 3lqi T 2-10 order
       Region 3lqj Q 2-7 order
       Region 3lqj T 2-7 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-16 Hetero trimer : O75151
       Region 3kqi B 2-7 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-16 Hetero dimer : IID00303Complex
       Region 2lbm C 2-16 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-16 Hetero trimer : Q96EQ9
       Region 4c1q C 2-8 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-16 Hetero dimer : Q9BTC0
       Region 4l7x U 2-8 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-16 Hetero tetramer : IID00327Complex
       Region 3zvy C 2-6 order
       Region 3zvy D 2-6 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-16 Hetero dimer : IID00489Complex
       Region 4llb C 2-16 order
       Region 4llb D 2-16 order
       Region 4lka B 2-13 order
       Region 4lk9 B 2-14 order
       Region 3v43 Q 2-8 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-16 Hetero dimer : IID00327Complex
       Region 3sow C 2-7 order
       Region 3sow D 2-7 order
       Region 3sou D 2-9 order
       Region 3sou E 2-9 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-16 Hetero dimer : Q8IE47
       Region 3u31 B 7-12 order
       Region 3u3d B 7-13 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-16 Hetero dimer : IID00360Complex
       Region 2ox0 C 8-15 order
       Region 2ox0 D 8-15 order
       Region 2oq6 C 8-15 order
       Region 2oq6 D 8-15 order
       Region 2ot7 C 8-15 order
       Region 2ot7 D 8-15 order
       Region 3u4s C 8-15 order
       Region 3u4s D 8-13 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-16 Hetero dimer : IID00128Complex
       Region 1o9s K 2-10 order
       Region 1o9s L 2-7 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-16 Hetero trimer : IID00255Complex
       Region 2vpg P 2-8 order
       Region 2vpg R 2-8 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-17 Hetero trimer : IID00009Complex
       Region 2x0l C 6-17 order
       Region 5h6r C 2-15 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-21 Hetero dimer : IID00505Complex
       Region 3u5n C 2-11 order
       Region 3u5n D 2-21 order
       Region 3u5p I 2-19 order
       Region 3u5p J 2-13 order
       Region 3u5p J 16-19 order
       Region 3u5p K 2-13 order
       Region 3u5p K 16-19 order
       Region 3u5p L 2-19 order
       Region 3u5p M 2-20 order
       Region 3u5p N 2-13 order
       Region 3u5p N 16-19 order
       Region 3u5p O 2-19 order
       Region 3u5p P 2-13 order
       Region 3u5p P 16-19 order
       Region 3u5o I 2-21 order
       Region 3u5o J 2-21 order
       Region 3u5o K 2-21 order
       Region 3u5o L 2-21 order
       Region 3u5o M 2-21 order
       Region 3u5o N 2-21 order
       Region 3u5o O 2-21 order
       Region 3u5o P 2-21 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-21 Hetero dimer : IID00418Complex
       Region 2kwj B 2-21 order
       Region 2kwk B 2-11 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-10,18-21 : IID00336Complex
       Region 3a1b A 2-10 order
       Region 3a1b A 18-21 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-30 Hetero tetramer : Q8VDS3
       Region 4x3k C 24-30 order
       Region 4x3k D 24-30 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-30 Hetero trimer : IID00336Complex
       Region 4qbq P 2-9 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-30 Hetero dimer : Q56A73
       Region 4uy4 C 2-7 order
       Region 4uy4 D 2-7 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-30 Hetero tetramer : Q7JXA8
       Region 4u68 D 5-11 order
       Region 4u68 E 5-11 order
       Region 4u68 F 5-11 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-30 Hetero dimer : IID00336Complex
       Region 4qbs P 2-8 order
       Region 4qbr E 2-8 order
       Region 4qbr P 2-8 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-30 Hetero tetramer : Q504Y3
       Region 4z0r D 2-11 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-30 Hetero dimer : O94953
       Region 4lxl D 8-15 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 2-30 Hetero dimer : Q86UU0,Q9BRQ0
       Region 4up0 F 2-7 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 4-12 Hetero tetramer : IID00500Complex
       Region 4i51 C 4-12 order
       Region 4i51 D 6-12 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 4-12 Hetero tetramer : IID00250Complex
       Region 5jin F 5-12 order
       Region 5jin G 4-12 order
       Region 5jiy F 5-12 order
       Region 5jiy G 4-12 order
       Region 5jj0 F 5-12 order
       Region 5jj0 G 4-12 order
       Region 5jhn G 4-12 order
       Region 5jhn F 5-12 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 4-25 Hetero octamer : IID00552Complex
       Region 5hjd B 15-21 order
       Region 5hjd D 15-21 order
       Region 5hjd F 16-20 order
       Region 5hjd H 16-20 order
       Region 5hjd I 16-20 order
       Region 5hjd J 16-21 order
       Region 5hjd L 15-21 order
       Region 5hjd M 15-21 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 4-25 Hetero dimer : IID00552Complex
       Region 5hjb B 4-9 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 4-25 Hetero dimer : IID00552Complex
       Region 2ndf B 13-25 order
       Region 2ndg B 13-25 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 5-14 Hetero dimer : IID00486Complex
       Region 3zg6 F 5-14 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 6-11 Hetero dimer : IID50064Complex
       Region 1q3l P 6-11 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 7-13 Hetero dimer : Q8IXJ6
       Region 4y6l C 7-13 order
       Region 4y6l D 7-13 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 7-14 Hetero dimer : IID00502Complex
       Region 3rig C 7-12 order
       Region 3rig D 7-12 order
       Region 4f56 C 7-13 order
       Region 4f56 D 7-13 order
       Region 4f4u C 7-13 order
       Region 4f4u D 7-13 order
       Region 3riy C 7-13 order
       Region 3riy D 7-14 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 7-16 Hetero dimer : IID00481Complex
       Region 4hon F 7-16 order
       Region 4hon G 8-14 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 8-15 Hetero tetramer : IID00061Complex
       Region 2c1j C 8-15 order
       Region 2c1j D 8-15 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 8-15 Hetero dimer : IID00061Complex
       Region 2c1n C 8-15 order
       Region 2c1n E 8-15 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 16-24 Hetero dimer : Q15059
       Region 5hjc B 16-24 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 18-34 Hetero dimer : IID00431Complex
       Region 3avr B 18-34 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 20-28 Hetero decamer : IID00360Complex
       Region 5d6y a 20-28 order
       Region 5d6y b 20-28 order
       Region 5d6y c 21-27 order
       Region 5d6y d 21-27 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 21-29 Hetero dimer : P55197
       Region 5dah C 21-29 order
       Region 5dah D 21-29 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 23-31 Hetero pentamer : IID00727Complex
       Region 5hyn D 23-31 order
       Region 5hyn I 23-31 order
       Region 5hyn O 23-31 order
       Region 5hyn T 23-31 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 23-33 Hetero dimer : IID00289Complex
       Region 3o34 B 23-33 order
       Region 3o35 E 26-30 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 25-30 Hetero dimer : Q03111
       Region 5j9s B 25-30 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 25-32 Hetero dimer : Q9ULM3
       Region 5iql B 25-32 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 26-33 Hetero dimer : IID90012Complex
       Region 3kmt G 26-33 order
       Region 3kmt H 26-33 order
       Region 3kmt I 26-33 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 30-38 Hetero dimer : Q8R5C8
       Region 4n4h B 30-40 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 30-38 Hetero trimer : P59997
       Region 4tn7 E 30-39 order
       Region 4tn7 F 30-39 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 32-38 Hetero dimer : IID00480Complex
       Region 4bd3 B 32-42 order
       Region 2cv5 A 1-38 disorder
SeqProS verified 32-38 Hetero dimer : IID00432Complex
       Region 2m0o B 32-42 order
       Region 2cv5 A 1-38 disorder
Seqphosphorylation
    4-4 Phosphothreonine; by HASPIN
    7-7 Phosphothreonine; by PKC
    11-11 Phosphoserine; alternate; by AURKB
    12-12 Phosphothreonine; by PKC and CHEK1
    29-29 Phosphoserine; alternate; by AURKB
    42-42 Phosphotyrosine
    58-58 Phosphoserine
    81-81 Phosphothreonine
    87-87 Phosphoserine
    108-108 Phosphothreonine
Seqacetylation
    5-5 N6-acetyllysine; alternate
    10-10 N6-acetyllysine; alternate
    15-15 N6-acetyllysine; alternate
    19-19 N6-acetyllysine; alternate
    24-24 N6-acetyllysine; alternate
    28-28 N6-acetyllysine; alternate
    37-37 N6-acetyllysine; alternate
    57-57 N6-acetyllysine; alternate
    80-80 N6-acetyllysine; alternate
    116-116 N6-acetyllysine; alternate
    123-123 N6-acetyllysine; alternate
 
Prediction
NeProc
Disorder 1-39
Order 40-136
ProS 1-39
AlphaFold
Disorder 1-3,8-35,135-136
Order 4-7,36-134
Pfam Hmmer
PF00125 58-132 9.6e-41
Function
Function in SwissProt
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Biological Process
Diagram with PDB data
H3C1/YWHAZMolecular basis for the recognition of phosphorylated and phosphoacetylated histone H3 by 14-3-3
See also
Diagram with PDB data
CTHT_0053230/CTHT_0029920/CTHT_0006210/H3C1/H3C1Structure of ctPRC2 in complex with H3K27me3 and H3K27M
EZH2/EED/SUZ12/H3C1/JARID2Structure of Human Polycomb Repressive Complex 2 (PRC2) with oncogenic histone H3K27M peptide