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IID00074
UniprotQ13772
ProteinNuclear receptor coactivator 4
GeneNCOA4
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
614
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 322-336 Hetero dimer : IID00020Complex
 Evidence X-RAY 1t5z B Reference
       Region 1t5z B 322-324 disorder
       Region 1t5z B 325-335 order
       Region 1t5z B 336-336 disorder
SeqProS possible 325-335 FXXLF motif Hetero dimer : IID00020Complex
       Region 1t5z B 325-335 order
 
Prediction
NeProc
Disorder 1-15,170-176,179-325,347-353,372-387,438-557
Order 16-169,177-178,326-346,354-371,388-437,558-568,576-614
ProS 5-12,179-206,215-231,242-263,270-274,284-290,300-310,321-325,347-353,438-447,453-465,478-509,529-542
AlphaFold
Disorder 1-12,161-224,226-357,365-407,417-425,427-428,431-557,563-563,565-614
Order 13-160,225-225,358-364,408-416,426-426,429-430,558-562,564-564
SEG 79-98 ,445-454
Function
Function in SwissProt
Enhances the androgen receptor transcriptional activity in prostate cancer cells. Ligand-independent coactivator of the peroxisome proliferator-activated receptor (PPAR) gamma.