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IID00121
 UniprotP22415
ProteinUpstream stimulatory factor 1
GeneUSF1
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 xml
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
310
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seqdisorder 197-260
 Evidence CD Reference
       Region 197-260 disorder
Seq 197-260 Homo dimer :
 Evidence X-RAY 1an4 B Reference
       Region 1an4 B 197-260 order
 Evidence X-RAY 1an4 A Reference
       Region 1an4 A 197-260 order
SeqProS verified 197-260 This region is ordered in the complex with DNA. Homo dimer :
       Region 1an4 A 197-260 order
       Region 1an4 B 197-260 order
       Region 197-260 disorder
 
Prediction
NeProc
Disorder 1-207,229-237
Order 208-228,238-310
ProS 45-50,58-66,94-98,113-121,156-164,178-188,193-207,229-237
AlphaFold
Disorder 1-63,65-194,230-237,302-310
Order 64-64,195-229,238-301
Pfam Hmmer
PF00010 200-255 3.9e-18
SEG 121-142 ,265-281
Function
Function in SwissProt
Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters.