Search Keyword:


Search option:


IID00131
 UniprotP12755
ProteinSki oncogene
GeneSKI
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
728
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 91-192 Monomer :
 Evidence X-RAY 1sbx A Reference
       Region 1sbx A 91-192 order
Seq 219-313 Hetero dimer : IID00132Complex
 Evidence X-RAY 1mr1 C Reference
       Region 1mr1 C 219-312 order
       Region 1mr1 C 313-313 disorder
 Evidence X-RAY 1mr1 D Reference
       Region 1mr1 D 219-312 order
       Region 1mr1 D 313-313 disorder
Seqphosphorylation
    383-383 Phosphoserine
    480-480 Phosphoserine
    432-432 Phosphoserine
    720-720 Phosphoserine
 
Prediction
NeProc
Disorder 1-96,199-213,319-384,389-569,648-659,709-728
Order 97-194,214-318,570-647,660-708
ProS 1-6,11-44,199-200,319-338,348-384,400-420,472-494,510-516,535-569,648-659,709-710
AlphaFold
Disorder 1-13,15-17,21-98,192-215,266-266,313-536,648-650,652-652,711-728
Order 14-14,18-20,99-191,216-265,267-312,537-647,651-651,653-710
Pfam Hmmer
PF02437 80-192 1.1e-77
SEG 43-93 ,202-217 ,414-425 ,480-509 ,518-540 ,621-632 ,679-699 ,712-728
Function
Function in SwissProt
May play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage. Functions as a repressor of TGF-beta signaling.