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IID00158
 UniprotP62308
ProteinSmall nuclear ribonucleoprotein G
GeneSNRPG
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
76
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-76 Hetero nonamer : IID00139Complex,IID00156Complex,IID00161Complex
 Evidence X-RAY 3cw1 5 Reference
       Region 3cw1 5 1-3 disorder
       Region 3cw1 5 4-76 order
 Evidence X-RAY 3cw1 3 Reference
       Region 3cw1 3 1-3 disorder
       Region 3cw1 3 4-76 order
 Evidence X-RAY 3cw1 G Reference
       Region 3cw1 G 1-3 disorder
       Region 3cw1 G 4-76 order
Seq 1-76 Hetero nonamer : IID00139Complex,IID00156Complex,IID00161Complex
 Evidence X-RAY 3cw1 4 Reference
       Region 3cw1 4 1-3 disorder
       Region 3cw1 4 4-76 order
Seq 1-76 Hetero hexamer : A1ZAW5,IID00156Complex
 Evidence X-RAY 4f7u J Reference
       Region 4f7u J 1-7 disorder
       Region 4f7u J 8-74 order
       Region 4f7u J 75-76 disorder
 Evidence X-RAY 4f7u G Reference
       Region 4f7u G 1-6 disorder
       Region 4f7u G 7-74 order
       Region 4f7u G 75-76 disorder
Seq 1-76 Hetero 36mer : IID00138Complex,IID00139Complex,IID00143Complex,IID00156Complex,IID00157Complex,IID00161Complex
 Evidence X-RAY 4pjo G Reference
       Region 4pjo G 1-2 disorder
       Region 4pjo G 3-76 order
 Evidence X-RAY 4pjo U Reference
       Region 4pjo U 1-3 disorder
       Region 4pjo U 4-50 order
       Region 4pjo U 51-52 disorder
       Region 4pjo U 53-76 order
 Evidence X-RAY 4pjo g Reference
       Region 4pjo g 1-3 disorder
       Region 4pjo g 4-76 order
 Evidence X-RAY 4pjo u Reference
       Region 4pjo u 4-76 order
Seq 1-76 Hetero nonamer : IID00156Complex,IID00161Complex
 Evidence X-RAY 3pgw J Reference
       Region 3pgw J 1-76 order
 Evidence X-RAY 3pgw G Reference
       Region 3pgw G 1-76 order
 
Prediction
NeProc
Disorder 1-5
Order 6-76
AlphaFold
Disorder 1-4
Order 5-76
Pfam Hmmer
PF01423 7-72 7.8e-26
Function
Function in SwissProt
Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161, PubMed:19325628, PubMed:23333303, PubMed:25555158, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346). Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (PubMed:11991638, PubMed:28502770, PubMed:28781166, PubMed:28076346). Is also a component of the minor U12 spliceosome (PubMed:15146077). As part of the U7 snRNP it is involved in histone 3'-end processing (PubMed:12975319).