Structure
atLeast majority ProS Experiment
:order disorder conflict PDB cluster ProS Pfam Domain SEG1249
order/disorder by at least rule
disorder by at least rule
order/disorder by majority rule
Seq 985-998 Hetero dimer : IID00042 Complex
Region 1t15 B 988-995 order
Region 1t29 B 985-996 order
Region 1t29 B 997-998 disorder
Seq 1129-1138 Hetero dimer : Q92547
Region 3al3 B 1129-1138 order
Seq ProS predicted 988-995 IID00042 Complex
Region 1t29 B 985-996 order
Region 1t15 B 988-995 order
Seq ProS predicted 1129-1138 Q92547
Region 3al3 B 1129-1138 order
1249-1249 N6-acetyllysine
Prediction
Function
Function in SwissProt
DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. Acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination. Involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1.
Biological Process
Diagram with PDB data BRIP1/BRCA1 Crystal Structure of the Brca1 BRCT Domains in Complex with the Phosphorylated Interacting Region from Bach1 Helicase
Hetero dimer : IID00042Complex
