SeqProS possible 80-143 The region of helix4 and 5 (80-143) is highly likely a random coil in the absence of TBP and DNA.
Hetero trimer : IID00367Complex,IID00385Complex
The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.