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IID00257
 UniprotO43312
ProteinMetastasis suppressor protein 1
GeneMTSS1
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
755
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 724-755 Hetero trimer : IID50082Complex,P00639
 Evidence X-RAY 2d1k C Reference
       Region 2d1k C 724-724 disorder
       Region 2d1k C 725-753 order
       Region 2d1k C 754-755 disorder
Seqphosphorylation
    261-261 Phosphoserine
    258-258 Phosphothreonine
    262-262 Phosphoserine
    271-271 Phosphoserine
    322-322 Phosphoserine
    425-425 Phosphothreonine
    603-603 Phosphothreonine
    644-644 Phosphoserine
    647-647 Phosphoserine
 
Prediction
NeProc
Disorder 1-8,126-158,242-739,747-755
Order 9-125,159-241,740-746
ProS 4-8,126-150,242-257,321-327,335-354,370-391,421-427,463-472,511-514,525-532,540-551,587-591,598-602,625-628,729-739,747-755
AlphaFold
Disorder 155-156,249-473,486-729,738-741,743-749,751-755
Order 1-154,157-248,474-485,730-737,742-742,750-750
Pfam Hmmer
PF08397 16-237 4.7e-130
PF02205 727-744 0.00091
SEG 253-305 ,437-455 ,471-483 ,608-624
Function
Function in SwissProt
May be related to cancer progression or tumor metastasis in a variety of organ sites, most likely through an interaction with the actin cytoskeleton.