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IID00268
UniprotP25791
ProteinRhombotin-2
GeneLMO2
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
158
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 9-158 Hetero dimer : P01764
 Evidence X-RAY 4kfz B Reference
       Region 4kfz B 9-156 order
       Region 4kfz B 157-158 disorder
 Evidence X-RAY 4kfz A Reference
       Region 4kfz A 9-10 disorder
       Region 4kfz A 11-156 order
       Region 4kfz A 157-158 disorder
Seq 25-156 Hetero tetramer : IID00282Complex,IID00541Complex,IID00543Complex
 Evidence X-RAY 2ypa C Reference
       Region 2ypa C 25-29 disorder
       Region 2ypa C 30-155 order
       Region 2ypa C 156-156 disorder
Seq 26-156 Hetero dimer : IID00282Complex
 Evidence X-RAY 2xjz C Reference
       Region 2xjz C 26-30 disorder
       Region 2xjz C 31-34 order
       Region 2xjz C 35-47 disorder
       Region 2xjz C 48-155 order
       Region 2xjz C 156-156 disorder
 Evidence X-RAY 2xjz B Reference
       Region 2xjz B 26-29 disorder
       Region 2xjz B 30-64 order
       Region 2xjz B 65-68 disorder
       Region 2xjz B 69-155 order
       Region 2xjz B 156-156 disorder
 Evidence X-RAY 2xjz E Reference
       Region 2xjz E 26-29 disorder
       Region 2xjz E 30-156 order
 Evidence X-RAY 2xjz D Reference
       Region 2xjz D 26-154 order
       Region 2xjz D 155-156 disorder
 Evidence X-RAY 2xjz A Reference
       Region 2xjz A 26-31 disorder
       Region 2xjz A 32-156 order
 Evidence X-RAY 2xjy A Reference
       Region 2xjy A 26-156 order
 
Prediction
NeProc
Disorder 1-26,155-158
Order 27-154
ProS 155-158
AlphaFold
Disorder 12-26,158-158
Order 1-11,27-157
Pfam Hmmer
PF00412 30-89 1.3e-13
PF00412 94-153 9.4e-23
Function
Function in SwissProt
Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state.