Search Keyword:


Search option:


IID00323
 UniprotQ1MX18
ProteinProtein inscuteable homolog
GeneINSC
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
579
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 70-116 Hetero dimer : IID00313Complex
 Evidence X-RAY 3sf4 F Reference
       Region 3sf4 F 70-115 order
       Region 3sf4 F 116-116 disorder
 Evidence X-RAY 3sf4 E Reference
       Region 3sf4 E 70-100 order
       Region 3sf4 E 101-108 disorder
       Region 3sf4 E 109-114 order
       Region 3sf4 E 115-116 disorder
 Evidence X-RAY 3sf4 D Reference
       Region 3sf4 D 70-70 disorder
       Region 3sf4 D 71-115 order
       Region 3sf4 D 116-116 disorder
Seqdisorder 70-116
 Evidence CD Reference
       Region 70-116 disorder
SeqProS verified 70-115 Hetero dimer : IID00313Complex
       Region 3sf4 D 71-115 order
       Region 3sf4 E 70-100 order
       Region 3sf4 E 109-114 order
       Region 3sf4 F 70-115 order
       Region 70-116 disorder
 
Prediction
NeProc
Disorder 1-28,176-180,576-579
Order 29-111,118-175,181-471,477-575
ProS 1-7,17-21,176-180,576-579
AlphaFold
Disorder 1-72,100-118,173-175,358-361,573-579
Order 73-99,119-172,176-357,362-572
SEG 107-125 ,338-352 ,531-544
Function
Function in SwissProt
May function as an adapter linking the Par3 complex to the GPSM1/GPSM2 complex (PubMed:16458856). Involved in spindle orientation during mitosis. May regulate cell proliferation and differentiation in the developing nervous system. May play a role in the asymmetric division of fibroblasts and participate in the process of stratification of the squamous epithelium (By similarity).