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IID00339
 UniprotP19883
ProteinFollistatin
GeneFST
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
344
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 30-317 Hetero tetramer : IID50111Complex
 Evidence X-RAY 3hh2 D Reference
       Region 3hh2 D 30-109 order
       Region 3hh2 D 110-112 disorder
       Region 3hh2 D 113-198 order
       Region 3hh2 D 199-202 disorder
       Region 3hh2 D 203-275 order
       Region 3hh2 D 276-280 disorder
       Region 3hh2 D 281-316 order
       Region 3hh2 D 317-317 disorder
 Evidence X-RAY 3hh2 C Reference
       Region 3hh2 C 30-198 order
       Region 3hh2 C 199-203 disorder
       Region 3hh2 C 204-275 order
       Region 3hh2 C 276-280 disorder
       Region 3hh2 C 281-317 order
Seq 30-317 Hetero tetramer : O95390
 Evidence X-RAY 5jhw D Reference
       Region 5jhw D 30-199 order
       Region 5jhw D 200-201 disorder
       Region 5jhw D 202-275 order
       Region 5jhw D 276-277 disorder
       Region 5jhw D 278-317 order
 Evidence X-RAY 5jhw C Reference
       Region 5jhw C 30-201 order
       Region 5jhw C 202-203 disorder
       Region 5jhw C 204-275 order
       Region 5jhw C 276-279 disorder
       Region 5jhw C 280-317 order
Seq 30-317 Hetero tetramer : IID00338Complex
 Evidence X-RAY 2b0u D Reference
       Region 2b0u D 30-102 order
       Region 2b0u D 103-104 disorder
       Region 2b0u D 105-124 order
       Region 2b0u D 125-127 disorder
       Region 2b0u D 128-199 order
       Region 2b0u D 200-200 disorder
       Region 2b0u D 201-276 order
       Region 2b0u D 277-278 disorder
       Region 2b0u D 279-317 order
 Evidence X-RAY 2b0u C Reference
       Region 2b0u C 30-126 order
       Region 2b0u C 127-127 disorder
       Region 2b0u C 128-317 order
Seq 30-344 Hetero pentamer : IID00338Complex
 Evidence X-RAY 2p6a C Reference
       Region 2p6a C 30-102 order
       Region 2p6a C 103-104 disorder
       Region 2p6a C 105-124 order
       Region 2p6a C 125-127 disorder
       Region 2p6a C 128-199 order
       Region 2p6a C 200-200 disorder
       Region 2p6a C 201-276 order
       Region 2p6a C 277-278 disorder
       Region 2p6a C 279-319 order
       Region 2p6a C 320-344 disorder
 Evidence X-RAY 2p6a D Reference
       Region 2p6a D 30-102 order
       Region 2p6a D 103-104 disorder
       Region 2p6a D 105-124 order
       Region 2p6a D 125-127 disorder
       Region 2p6a D 128-276 order
       Region 2p6a D 277-278 disorder
       Region 2p6a D 279-328 order
       Region 2p6a D 329-344 disorder
 
Prediction
NeProc
Disorder 1-7,325-335,341-344
Order 8-324,336-340
ProS 325-335,341-344
AlphaFold
Disorder 1-28,277-279,319-344
Order 29-276,280-318
Pfam Hmmer
PF00050 118-164 5e-17
PF00050 192-239 3e-16
PF00050 270-316 3.2e-18
SEG 11-19 ,321-333
Function
Function in SwissProt
Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH).