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IID00351
 UniprotP16581
ProteinE-selectin
GeneSELE
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 xml
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
610
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 22-183 Monomer :
 Evidence X-RAY 1g1t A Reference
       Region 1g1t A 22-178 order
 Evidence X-RAY 1esl A Reference
       Region 1esl A 22-178 order
       Region 1esl A 179-183 disorder
Seq 22-301 Monomer :
 Evidence X-RAY 4csy B Reference
       Region 4csy B 22-301 order
 Evidence X-RAY 4csy A Reference
       Region 4csy A 22-301 order
 Evidence X-RAY 4c16 B Reference
       Region 4c16 B 22-301 order
 Evidence X-RAY 4c16 A Reference
       Region 4c16 A 22-301 order
 
Prediction
NeProc
Disorder 1-5,597-600
Order 6-596,601-610
ProS 1-5,597-600
AlphaFold
Disorder 1-20,257-259,383-386,499-499,551-610
Order 21-256,260-382,387-498,500-550
Pfam Hmmer
PF00059 29-140 4.3e-49
PF00008 143-174 1.5e-08
PF00084 180-237 1e-10
PF00084 242-299 1.5e-12
PF00084 304-362 1e-15
PF00084 367-425 8.7e-16
PF00084 430-488 9.1e-11
PF00084 493-547 1.4e-09
SEG 557-572
Function
Function in SwissProt
Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis.