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IID00385
 UniprotQ14919
ProteinDr1-associated corepressor
GeneDRAP1
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
205
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-77 Hetero trimer : IID00206Complex,IID00367Complex
 Evidence X-RAY 1jfi A Reference
       Region 1jfi A 1-9 disorder
       Region 1jfi A 10-60 order
       Region 1jfi A 61-63 disorder
       Region 1jfi A 64-75 order
       Region 1jfi A 76-77 disorder
 
Prediction
NeProc
Disorder 1-8,88-205
Order 9-87
ProS 88-94,149-152,199-205
AlphaFold
Disorder 1-2,5-5,95-171,173-173,176-176,179-183,193-193,196-201,203-203,205-205
Order 3-4,6-94,172-172,174-175,177-178,184-192,194-195,202-202,204-204
Pfam Hmmer
PF00808 10-74 9.1e-22
SEG 106-127 ,134-168 ,171-195
Function
Function in SwissProt
The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own.