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IID00425
 UniprotO00287
ProteinRegulatory factor X-associated protein
GeneRFXAP
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
272
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 214-272 Hetero trimer : IID00452Complex
 Evidence NMR 2kw3 C Reference
       Region 2kw3 C 214-272 order
       Region 2kw3 C 214-223 high_rmsd
       Region 2kw3 C 260-272 high_rmsd
 
Prediction
NeProc
Disorder 1-218,255-272
Order 219-254
ProS 1-8,45-60,69-77,139-152,157-185,196-218,255-258,266-272
AlphaFold
Disorder 1-42,44-45,47-47,52-137,153-154,185-203,205-205,208-221,266-272
Order 43-43,46-46,48-51,138-152,155-184,204-204,206-207,222-265
SEG 18-42 ,76-91 ,118-138 ,163-178 ,246-266
Function
Function in SwissProt
Part of the RFX complex that binds to the X-box of MHC II promoters.
Biological Process
See also
Diagram with PDB data
RFXANK/FRX5Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human RFXANK