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IID00469
 UniprotQ13363
ProteinC-terminal-binding protein 1
GeneCTBP1
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS xml
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
440
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 28-353 Monomer :
 Evidence X-RAY 1mx3 A Reference
       Region 1mx3 A 28-352 order
       Region 1mx3 A 353-353 disorder
Seq 28-353 Homo dimer :
 Evidence X-RAY 4u6s A Reference
       Region 4u6s A 28-353 order
 Evidence X-RAY 4u6q A Reference
       Region 4u6q A 28-353 order
 Evidence X-RAY 4lce A Reference
       Region 4lce A 28-353 order
Seq 28-353 Homo tetramer :
 Evidence X-RAY 4u6s A Reference
       Region 4u6s A 28-353 order
Seqphosphorylation
    300-300 Phosphoserine
    422-422 Phosphoserine; by HIPK2
 
Prediction
NeProc
Disorder 1-6,388-440
Order 7-381
ProS 6-6,397-400,421-425,432-440
AlphaFold
Disorder 1-25,358-440
Order 26-357
Pfam Hmmer
PF02826 133-317 2.7e-74
SEG 323-343 ,412-423
Function
Function in SwissProt
Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation.