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IID00510
 UniprotP23634
ProteinPlasma membrane calcium-transporting ATPase 4
GeneATP2B4
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
1241
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1086-1104 Hetero dimer : IID50309Complex
 Evidence NMR 1cff B Reference
       Region 1cff B 1086-1104 order
       Region 1cff B 1086-1086 high_rmsd
Seq 1086-1113 Hetero dimer : IID00706Complex
 Evidence NMR 2kne B Reference
       Region 2kne B 1086-1086 high_rmsd
       Region 2kne B 1086-1113 order
Seqphosphorylation
    1102-1102 Phosphothreonine; by PKC
    328-328 Phosphoserine
    13-13 Phosphoserine
 
Prediction
NeProc
Disorder 1-13,127-143,279-348,1065-1084,1117-1241
Order 14-126,144-278,349-1064,1085-1116
ProS 4-13,130-135,279-289,295-301,307-337,1076-1084,1141-1187,1212-1221,1232-1241
AlphaFold
Disorder 1-21,88-88,120-120,122-148,173-173,176-177,180-180,238-238,241-243,287-350,522-526,775-775,951-955,1052-1241
Order 22-87,89-119,121-121,149-172,174-175,178-179,181-237,239-240,244-286,351-521,527-774,776-950,956-1051
Pfam Hmmer
PF00690 39-121 5.6e-24
PF00122 154-455 2.6e-38
PF00702 459-806 1.9e-17
PF00689 902-1053 4e-26
SEG 106-120 ,291-303 ,335-351 ,1175-1192 ,1224-1237
Function
Function in SwissProt
Calcium/calmodulin-regulated and magnesium-dependent enzyme that catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell (PubMed:8530416). By regulating sperm cell calcium homeostasis, may play a role in sperm motility (By similarity).