IDEAL List

IDEAL

IID00533
UniprotO95400
ProteinCD2 antigen cytoplasmic tail-binding protein 2
GeneCD2BP2
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
Network xml rdf

Structure

Experiment

:order disorder conflict PDB cluster ProS Pfam Domain SEG

341

order/disorder by at least rule

disorder by at least rule

order by at least rule

order/disorder by majority rule

Seqdisorder 256-279

Evidence NMR

This region is described to be disordered in the free state (PubMed=10404223). Reference

Region 256-279 disorder

Seq 262-341 Hetero dimer : IID00559Complex

Evidence X-RAY 1syx F Reference

Region 1syx F 262-279 disorder

Region 1syx F 280-341 order

Evidence X-RAY 1syx D Reference

Region 1syx D 262-279 disorder

Region 1syx D 280-341 order

Evidence X-RAY 1syx B Reference

Region 1syx B 262-279 disorder

Region 1syx B 280-341 order

Seq 280-341 Monomer :

Evidence NMR 1gyf A Reference

Region 1gyf A 280-341 order

Seq 280-341 Hetero dimer : P06729

Evidence NMR 1l2z A Reference

Region 1l2z A 280-341 order

Seq 280-341 Hetero trimer : IID00559Complex

Evidence X-RAY 4bws F Reference

Region 4bws F 280-341 order

Evidence X-RAY 4bws C Reference

Region 4bws C 280-341 order

Seqphosphorylation

46-46 Phosphoserine

49-49 Phosphoserine

118-118 Phosphoserine

194-194 Phosphoserine

195-195 Phosphoserine

Seqacetylation

44-44 N6-acetyllysine

Prediction

NeProc

Disorder 1-87,130-151,160-172,177-194,234-279

Order 88-129,152-159,173-176,195-233,280-341

ProS 5-11,28-39,61-87,130-138,160-172,177-181,189-194,239-261

AlphaFold

Disorder 1-63,112-112,114-114,131-131,133-151,181-194,233-249,251-251,253-279

Order 64-111,113-113,115-130,132-132,152-180,195-232,250-250,252-252,280-341

Pfam Hmmer

PF02213 281-338 2.1e-27

SEG 13-19 ,48-61 ,157-166 ,172-189 ,252-265

Function

Function in SwissProt

Involved in pre-mRNA splicing as component of the U5 snRNP complex that is involved in spliceosome assembly.