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IID00543
 UniprotP17542
ProteinT-cell acute lymphocytic leukemia protein 1
GeneTAL1
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
331
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 180-253 Hetero tetramer : IID00268Complex,IID00541Complex
 Evidence X-RAY 2ypa A Reference
       Region 2ypa A 180-181 disorder
       Region 2ypa A 182-248 order
       Region 2ypa A 249-253 disorder
Seq 180-253 Hetero dimer : IID00541Complex
 Evidence X-RAY 2ypb A Reference
       Region 2ypb A 180-180 disorder
       Region 2ypb A 181-247 order
       Region 2ypb A 248-253 disorder
Seqphosphorylation
    122-122 Phosphoserine
    172-172 Phosphoserine
    12-12 Phosphoserine
 
Prediction
NeProc
Disorder 1-189,247-331
Order 190-246
ProS 31-42,145-161,275-307,315-331
AlphaFold
Disorder 1-4,6-181,252-331
Order 5-5,182-251
Pfam Hmmer
PF00010 188-240 7.3e-21
SEG 55-72 ,96-106 ,121-137 ,263-275
Function
Function in SwissProt
Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation (By similarity).