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IID00556
UniprotP52657
ProteinTranscription initiation factor IIA subunit 2
GeneGTF2A2
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
109
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 2-103 Monomer : IID00555Complex
 Evidence X-RAY 5m4s A Reference
       Region 5m4s A 2-103 order
Seq 2-109 Hetero tetramer : IID00367Complex,IID00555Complex
 Evidence X-RAY 1nvp D Reference
       Region 1nvp D 2-2 disorder
       Region 1nvp D 3-99 order
       Region 1nvp D 100-109 disorder
 
Prediction
NeProc
Disorder 102-109
Order 1-101
AlphaFold
Disorder 102-109
Order 1-101
Pfam Hmmer
PF02268 1-49 7.2e-34
PF02751 51-100 3e-33
Function
Function in SwissProt
TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.