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IID00562
 UniprotQ05BQ5
ProteinMBT domain-containing protein 1
GeneMBTD1
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
628
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 130-566 Monomer :
 Evidence X-RAY 3feo B Reference
       Region 3feo B 130-140 disorder
       Region 3feo B 141-184 order
       Region 3feo B 185-189 disorder
       Region 3feo B 190-226 order
       Region 3feo B 227-227 disorder
       Region 3feo B 228-237 order
       Region 3feo B 238-238 disorder
       Region 3feo B 239-326 order
       Region 3feo B 327-328 disorder
       Region 3feo B 329-351 order
       Region 3feo B 352-362 disorder
       Region 3feo B 363-376 order
       Region 3feo B 377-380 disorder
       Region 3feo B 381-561 order
       Region 3feo B 562-566 disorder
 Evidence X-RAY 3feo A Reference
       Region 3feo A 130-140 disorder
       Region 3feo A 141-185 order
       Region 3feo A 186-189 disorder
       Region 3feo A 190-352 order
       Region 3feo A 353-361 disorder
       Region 3feo A 362-424 order
       Region 3feo A 425-425 disorder
       Region 3feo A 426-561 order
       Region 3feo A 562-566 disorder
Seq 130-566 Hetero trimer : IID00234Complex
 Evidence X-RAY 4c5i B Reference
       Region 4c5i B 130-139 disorder
       Region 4c5i B 140-353 order
       Region 4c5i B 354-361 disorder
       Region 4c5i B 362-562 order
       Region 4c5i B 563-566 disorder
 Evidence X-RAY 4c5i A Reference
       Region 4c5i A 130-134 disorder
       Region 4c5i A 135-355 order
       Region 4c5i A 356-360 disorder
       Region 4c5i A 361-562 order
       Region 4c5i A 563-566 disorder
Seqacetylation
    115-115 N6-acetyllysine
 
Prediction
NeProc
Disorder 1-47,69-138,568-591
Order 48-68,139-567,592-628
ProS 1-11,69-84,93-97,121-127,568-576,588-591
AlphaFold
Disorder 1-50,84-139,356-361,563-628
Order 51-83,140-355,362-562
Pfam Hmmer
PF02820 184-254 1.2e-07
PF02820 289-355 3.6e-15
PF02820 388-465 3e-25
PF02820 496-566 2.3e-42
SEG 7-24 ,75-90 ,114-130 ,562-583
Function
Function in SwissProt
Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility (By similarity). Specifically binds to monomethylated and dimethylated 'Lys-20' on histone H4.