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IID00572
 UniprotQ7Z5R6
ProteinAmyloid beta A4 precursor protein-binding family B member 1-interacting protein
GeneAPBB1IP
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
666
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-31 Hetero dimer : P12003
 Evidence X-RAY 3zdl B Reference
       Region 3zdl B 1-6 disorder
       Region 3zdl B 7-31 order
Seq 7-30 Hetero dimer : Q9Y490
 Evidence NMR 2mwn A Reference
       Region 2mwn A 7-30 order
       Region 2mwn A 25-30 high_rmsd
Seqphosphorylation
    531-531 Phosphoserine
    528-528 Phosphothreonine
    526-526 Phosphoserine
    55-55 Phosphoserine
 
Prediction
NeProc
Disorder 1-148,283-289,434-666
Order 149-282,290-433
ProS 4-29,42-55,63-81,283-289,439-444,461-468,579-585,647-662
AlphaFold
Disorder 1-4,20-27,34-43,90-130,132-149,277-288,442-555,562-568,570-571,573-601,607-650,661-666
Order 5-19,28-33,44-89,131-131,150-276,289-441,556-561,569-569,572-572,602-606,651-660
Pfam Hmmer
PF00788 176-263 4.8e-16
PF00169 311-419 1.4e-12
SEG 32-39 ,58-74 ,125-182 ,509-529 ,547-588 ,599-633 ,637-646
Function
Function in SwissProt
Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion.