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IID00575
 UniprotQ8WV92
ProteinMIT domain-containing protein 1
GeneMITD1
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
249
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-249 Hetero tetramer : IID00253Complex
 Evidence X-RAY 2ymb A Reference
       Region 2ymb A 1-88 disorder
       Region 2ymb A 89-143 order
       Region 2ymb A 144-145 disorder
       Region 2ymb A 146-243 order
       Region 2ymb A 244-249 disorder
 Evidence X-RAY 2ymb B Reference
       Region 2ymb B 1-88 disorder
       Region 2ymb B 89-143 order
       Region 2ymb B 144-145 disorder
       Region 2ymb B 146-243 order
       Region 2ymb B 244-249 disorder
 Evidence X-RAY 2ymb C Reference
       Region 2ymb C 1-9 disorder
       Region 2ymb C 10-141 order
       Region 2ymb C 142-144 disorder
       Region 2ymb C 145-158 order
       Region 2ymb C 159-161 disorder
       Region 2ymb C 162-244 order
       Region 2ymb C 245-249 disorder
 Evidence X-RAY 2ymb D Reference
       Region 2ymb D 1-9 disorder
       Region 2ymb D 10-143 order
       Region 2ymb D 144-145 disorder
       Region 2ymb D 146-159 order
       Region 2ymb D 160-161 disorder
       Region 2ymb D 162-244 order
       Region 2ymb D 245-249 disorder
Seq 9-85 Hetero dimer : IID00253Complex
 Evidence X-RAY 4a5x B Reference
       Region 4a5x B 9-81 order
       Region 4a5x B 82-85 disorder
 Evidence X-RAY 4a5x A Reference
       Region 4a5x A 9-9 disorder
       Region 4a5x A 10-82 order
       Region 4a5x A 83-85 disorder
Seq 90-243 Homo dimer :
 Evidence X-RAY 4a5z D Reference
       Region 4a5z D 90-143 order
       Region 4a5z D 144-145 disorder
       Region 4a5z D 146-243 order
 Evidence X-RAY 4a5z B Reference
       Region 4a5z B 90-143 order
       Region 4a5z B 144-145 disorder
       Region 4a5z B 146-243 order
 Evidence X-RAY 4a5z C Reference
       Region 4a5z C 90-143 order
       Region 4a5z C 144-145 disorder
       Region 4a5z C 146-243 order
 Evidence X-RAY 4a5z A Reference
       Region 4a5z A 90-143 order
       Region 4a5z A 144-145 disorder
       Region 4a5z A 146-243 order
 
Prediction
NeProc
Disorder 1-10,80-98
Order 11-79,99-249
ProS 80-98
AlphaFold
Disorder 1-8,244-249
Order 9-243
Pfam Hmmer
PF04212 49-77 2.3e-10
Function
Function in SwissProt
Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT-III complex.