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IID00605
 UniprotQ16667
ProteinCyclin-dependent kinase inhibitor 3
GeneCDKN3
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
212
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-212 Homo hexamer :
 Evidence X-RAY 1fpz F Reference
       Region 1fpz F 1-22 disorder
       Region 1fpz F 23-200 order
       Region 1fpz F 201-212 disorder
 Evidence X-RAY 1fpz E Reference
       Region 1fpz E 1-24 disorder
       Region 1fpz E 25-200 order
       Region 1fpz E 201-212 disorder
 Evidence X-RAY 1fpz D Reference
       Region 1fpz D 1-22 disorder
       Region 1fpz D 23-200 order
       Region 1fpz D 201-212 disorder
 Evidence X-RAY 1fpz C Reference
       Region 1fpz C 1-22 disorder
       Region 1fpz C 23-200 order
       Region 1fpz C 201-212 disorder
 Evidence X-RAY 1fpz B Reference
       Region 1fpz B 1-24 disorder
       Region 1fpz B 25-200 order
       Region 1fpz B 201-212 disorder
 Evidence X-RAY 1fpz A Reference
       Region 1fpz A 1-24 disorder
       Region 1fpz A 25-200 order
       Region 1fpz A 201-212 disorder
Seq 1-212 Hetero dimer : IID00034Complex
 Evidence X-RAY 1fq1 A Reference
       Region 1fq1 A 1-20 disorder
       Region 1fq1 A 21-203 order
       Region 1fq1 A 204-212 disorder
 
Prediction
NeProc
Disorder 1-23,204-212
Order 24-203
ProS 12-23,204-212
AlphaFold
Disorder 1-20,210-212
Order 21-209
Pfam Hmmer
PF05706 1-207 1.3e-169
SEG 201-212
Function
Function in SwissProt
May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. Dephosphorylates CDK2 at 'Thr-160' in a cyclin-dependent manner.