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IID00617
 UniprotP35236
ProteinTyrosine-protein phosphatase non-receptor type 7
GenePTPN7
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
360
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 37-52 Hetero dimer : IID50321Complex
 Evidence X-RAY 2gph B Reference
       Region 2gph B 37-52 order
Seq 65-360 Hetero dimer : P28482
 Evidence X-RAY 3d44 A Reference
       Region 3d44 A 65-142 order
       Region 3d44 A 143-145 disorder
       Region 3d44 A 146-198 order
       Region 3d44 A 199-203 disorder
       Region 3d44 A 204-356 order
       Region 3d44 A 357-360 disorder
 Evidence X-RAY 3d42 A Reference
       Region 3d42 A 65-198 order
       Region 3d42 A 199-201 disorder
       Region 3d42 A 202-356 order
       Region 3d42 A 357-360 disorder
Seq 65-360 Monomer :
 Evidence X-RAY 1zc0 A Reference
       Region 1zc0 A 65-65 disorder
       Region 1zc0 A 66-199 order
       Region 1zc0 A 200-203 disorder
       Region 1zc0 A 204-355 order
       Region 1zc0 A 356-360 disorder
 Evidence X-RAY 2qdp A Reference
       Region 2qdp A 65-356 order
       Region 2qdp A 357-360 disorder
 Evidence X-RAY 2qdm A Reference
       Region 2qdm A 65-65 disorder
       Region 2qdm A 66-197 order
       Region 2qdm A 198-203 disorder
       Region 2qdm A 204-357 order
       Region 2qdm A 358-360 disorder
 Evidence X-RAY 2qdc A Reference
       Region 2qdc A 65-65 disorder
       Region 2qdc A 66-197 order
       Region 2qdc A 198-204 disorder
       Region 2qdc A 205-356 order
       Region 2qdc A 357-360 disorder
 Evidence X-RAY 3o4u A Reference
       Region 3o4u A 65-142 order
       Region 3o4u A 143-144 disorder
       Region 3o4u A 145-195 order
       Region 3o4u A 196-204 disorder
       Region 3o4u A 205-256 order
       Region 3o4u A 257-261 disorder
       Region 3o4u A 262-356 order
       Region 3o4u A 357-360 disorder
 Evidence X-RAY 3o4t A Reference
       Region 3o4t A 65-196 order
       Region 3o4t A 197-203 disorder
       Region 3o4t A 204-255 order
       Region 3o4t A 256-260 disorder
       Region 3o4t A 261-357 order
       Region 3o4t A 358-360 disorder
 Evidence X-RAY 3o4s A Reference
       Region 3o4s A 65-357 order
       Region 3o4s A 358-360 disorder
 Evidence X-RAY 2hvl A Reference
       Region 2hvl A 65-197 order
       Region 2hvl A 198-203 disorder
       Region 2hvl A 204-355 order
       Region 2hvl A 356-360 disorder
 Evidence X-RAY 2gp0 A Reference
       Region 2gp0 A 65-199 order
       Region 2gp0 A 200-203 disorder
       Region 2gp0 A 204-356 order
       Region 2gp0 A 357-360 disorder
 Evidence X-RAY 2a3k A Reference
       Region 2a3k A 65-139 order
       Region 2a3k A 140-147 disorder
       Region 2a3k A 148-198 order
       Region 2a3k A 199-204 disorder
       Region 2a3k A 205-276 order
       Region 2a3k A 277-284 disorder
       Region 2a3k A 285-358 order
Seqphosphorylation
    44-44 Phosphoserine
    93-93 Phosphoserine
    66-66 Phosphothreonine
    143-143 Phosphoserine
    110-110 Phosphoserine
 
Prediction
NeProc
Disorder 1-65,356-360
Order 66-278,283-355
ProS 1-7,33-65
AlphaFold
Disorder 1-51,53-64,141-144,280-282,357-360
Order 52-52,65-140,145-279,283-356
Pfam Hmmer
PF00102 119-349 9.1e-117
Function
Function in SwissProt
Protein phosphatase that acts preferentially on tyrosine-phosphorylated MAPK1. Plays a role in the regulation of T and B-lymphocyte development and signal transduction.