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IID00618
UniprotQ15744
ProteinCCAAT/enhancer-binding protein epsilon
GeneCEBPE
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
281
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 37-61 Monomer : IID00070Complex
 Evidence X-RAY 3t92 A Reference
       Region 3t92 A 37-59 order
       Region 3t92 A 60-61 disorder
Seqphosphorylation
    181-181 Phosphoserine
 
Prediction
NeProc
Disorder 1-33,44-51,59-221,271-281
Order 34-43,52-58,222-270
ProS 1-13,29-33,44-51,63-106,122-131,137-149,200-221,274-281
AlphaFold
Disorder 1-38,45-45,48-55,57-198,270-281
Order 39-44,46-47,56-56,199-269
Pfam Hmmer
PF07716 203-256 2.5e-18
Function
Function in SwissProt
Transcriptional activator (PubMed:26019275). C/EBP are DNA-binding proteins that recognize two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Required for the promyelocyte-myelocyte transition in myeloid differentiation (PubMed:10359588).