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IID00628
 UniprotP43627
ProteinKiller cell immunoglobulin-like receptor 2DL2
GeneKIR2DL2
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
348
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 22-221 Hetero pentamer : IID00153Complex,P04222
 Evidence X-RAY 1efx E Reference
       Region 1efx E 22-24 disorder
       Region 1efx E 25-221 order
 Evidence X-RAY 1efx D Reference
       Region 1efx D 22-24 disorder
       Region 1efx D 25-221 order
Seq 25-221 Monomer :
 Evidence X-RAY 2dli A Reference
       Region 2dli A 25-25 disorder
       Region 2dli A 26-221 order
 Evidence X-RAY 2dl2 A Reference
       Region 2dl2 A 26-221 order
 
Prediction
NeProc
Disorder 1-6,224-242,266-348
Order 7-223,243-265
ProS 1-6,242-242,266-319,324-348
AlphaFold
Disorder 1-25,223-249,269-348
Order 26-222,250-268
Pfam Hmmer
PF00047 42-102 7.8e-06
PF00047 142-200 2.1e-05
SEG 254-264
Function
Function in SwissProt
Receptor on natural killer (NK) cells for HLA-Cw1, 3, 7, and 8 allotypes. Inhibits the activity of NK cells thus preventing cell lysis.