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IID00634
 UniprotP62253
ProteinUbiquitin-conjugating enzyme E2 G1
GeneUBE2G1
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 xml
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
170
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 8-160 Monomer :
 Evidence X-RAY 2awf A Reference
       Region 2awf A 8-97 order
       Region 2awf A 98-106 disorder
       Region 2awf A 107-131 order
       Region 2awf A 132-160 disorder
Seqacetylation
    2-2 N-acetylthreonine; in Ubiquitin-conjugating enzyme E2 G1
    1-1 N-acetylmethionine
 
Prediction
NeProc
Disorder 1-6,164-170
Order 7-163
ProS 164-170
AlphaFold
Disorder 1-2,170-170
Order 3-169
Pfam Hmmer
PF00179 9-161 2.4e-83
SEG 3-17
Function
Function in SwissProt
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. May be involved in degradation of muscle-specific proteins. Mediates polyubiquitination of CYP3A4.