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IID00635
 UniprotQ8WVN8
ProteinUbiquitin-conjugating enzyme E2 Q2
GeneUBE2Q2
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 xml
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
375
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 197-363 Monomer :
 Evidence X-RAY 1zuo B Reference
       Region 1zuo B 197-200 disorder
       Region 1zuo B 201-340 order
       Region 1zuo B 341-363 disorder
 Evidence X-RAY 1zuo A Reference
       Region 1zuo A 197-200 disorder
       Region 1zuo A 201-362 order
       Region 1zuo A 363-363 disorder
 
Prediction
NeProc
Disorder 46-52,127-132,161-199,372-375
Order 1-45,53-126,133-160,200-371
ProS 127-132,171-192,372-375
AlphaFold
Disorder 1-1,42-50,89-91,127-170,369-375
Order 2-41,51-88,92-126,171-368
Pfam Hmmer
PF00179 208-361 8.6e-05
SEG 45-56 ,134-152
Function
Function in SwissProt
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination.