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IID00640
 UniprotQ96LR5
ProteinUbiquitin-conjugating enzyme E2 E2
GeneUBE2E2
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 xml
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
201
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 55-201 Monomer :
 Evidence X-RAY 1y6l A Reference
       Region 1y6l A 55-201 order
 Evidence X-RAY 1y6l B Reference
       Region 1y6l B 55-201 order
 Evidence X-RAY 1y6l C Reference
       Region 1y6l C 55-201 order
Seqphosphorylation
    19-19 Phosphoserine
    18-18 Phosphoserine
    15-15 Phosphoserine
    11-11 Phosphoserine
Seqacetylation
    2-2 N-acetylserine
 
Prediction
NeProc
Disorder 1-57
Order 58-201
AlphaFold
Disorder 1-51
Order 52-201
Pfam Hmmer
PF00179 59-196 2.5e-76
SEG 9-42 ,44-58
Function
Function in SwissProt
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Catalyzes the ISGylation of influenza A virus NS1 protein.