Search Keyword:


Search option:


IID00647
 UniprotP02749
ProteinBeta-2-glycoprotein 1
GeneAPOH
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
345
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 20-345 Monomer :
 Evidence X-RAY 1qub A Reference
       Region 1qub A 20-329 order
       Region 1qub A 337-345 order
 Evidence X-RAY 1c1z A Reference
       Region 1c1z A 20-345 order
Seq 203-345 Monomer :
 Evidence X-RAY 4jhs A Reference
       Region 4jhs A 203-203 disorder
       Region 4jhs A 204-345 order
Seq 261-345 Monomer :
 Evidence NMR 1g4g A Reference
       Region 1g4g A 261-345 order
 Evidence NMR 1g4f A Reference
       Region 1g4f A 261-345 order
       Region 1g4f A 330-335 high_rmsd
 Evidence X-RAY 3op8 B Reference
       Region 3op8 B 263-345 order
 Evidence X-RAY 3op8 A Reference
       Region 3op8 A 263-345 order
Seq 263-345 Hetero dimer : IID00646Complex
 Evidence NMR 2kri A Reference
       Region 2kri A 263-263 disorder
       Region 2kri A 264-345 order
Seqdisorder 329-339
 Evidence NMR Reference
       Region 329-339 disorder
SeqProS verified 329-339 Hetero dimer : IID00646Complex
       Region 2kri A 264-345 order
       Region 329-339 disorder
 
Prediction
NeProc
Disorder 1-15,340-345
Order 16-339
ProS 1-15,340-345
AlphaFold
Disorder 1-20,330-335
Order 21-329,336-345
Pfam Hmmer
PF00084 23-79 2.1e-11
PF00084 84-137 3.4e-18
PF00084 142-200 9.1e-11
PF00084 205-260 8.3e-18
SEG 139-148
Function
Function in SwissProt
Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.