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IID00678
UniprotQ99633
ProteinPre-mRNA-splicing factor 18
GenePRPF18
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
xml
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
342
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 60-122 Monomer :
 Evidence NMR 2dk4 A Reference
       Region 2dk4 A 60-122 order
       Region 2dk4 A 60-73 high_rmsd
       Region 2dk4 A 119-122 high_rmsd
Seqacetylation
    1-1 N-acetylmethionine
 
Prediction
NeProc
Disorder 1-78,140-169
Order 79-139,170-342
ProS 1-16,24-48,140-143,151-169
AlphaFold
Disorder 1-1,20-20,22-23,46-76,117-124,144-157,159-163,277-287,293-306,339-342
Order 2-19,21-21,24-45,77-116,125-143,158-158,164-276,288-292,307-338
Pfam Hmmer
PF02840 188-332 1e-107
Function
Function in SwissProt
Participates in the second step of pre-mRNA splicing.