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IID00681
 UniprotQ9HBX9
ProteinRelaxin receptor 1
GeneRXFP1
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
757
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 23-63 Monomer :
 Evidence NMR 2jm4 A Reference
       Region 2jm4 A 23-63 order
       Region 2jm4 A 23-25 high_rmsd
       Region 2jm4 A 63-63 high_rmsd
Seq 28-39 Monomer : IID00646Complex
 Evidence NMR 2m7p A Reference
       Region 2m7p A 28-39 order
 
Prediction
NeProc
Disorder 522-528,611-617,698-732
Order 1-521,529-610,618-697,733-757
ProS 522-528,698-732
AlphaFold
Disorder 1-25,44-44,68-92,393-395,399-399,434-436,519-523,567-573,610-613,704-757
Order 26-43,45-67,93-392,396-398,400-433,437-518,524-566,574-609,614-703
Pfam Hmmer
PF00057 25-62 2.1e-10
PF00001 422-681 3.1e-14
Function
Function in SwissProt
Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.