Search Keyword:


Search option:


IID00684
 UniprotQ9UGI8
ProteinTestin
GeneTES
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
421
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 296-421 Hetero trimer : IID00687Complex,Q8N8S7
 Evidence X-RAY 2xqn T Reference
       Region 2xqn T 296-296 disorder
       Region 2xqn T 297-421 order
Seq 357-421 Hetero octamer : Q8N8S7
 Evidence X-RAY 2iyb E Reference
       Region 2iyb E 357-357 disorder
       Region 2iyb E 358-421 order
 Evidence X-RAY 2iyb F Reference
       Region 2iyb F 357-357 disorder
       Region 2iyb F 358-420 order
       Region 2iyb F 421-421 disorder
 Evidence X-RAY 2iyb G Reference
       Region 2iyb G 357-420 order
       Region 2iyb G 421-421 disorder
 Evidence X-RAY 2iyb H Reference
       Region 2iyb H 357-357 disorder
       Region 2iyb H 358-420 order
       Region 2iyb H 421-421 disorder
 
Prediction
NeProc
Disorder 1-11,72-76,93-113,203-225
Order 12-71,77-92,114-202,226-421
ProS 1-11,72-76,93-103,110-113,203-225
AlphaFold
Disorder 1-16,54-56,79-81,98-104,200-232
Order 17-53,57-78,82-97,105-199,233-421
Pfam Hmmer
PF06297 91-196 1.3e-57
PF00412 236-298 6.9e-14
PF00412 301-358 2.4e-20
PF00412 361-421 0.00015
Function
Function in SwissProt
Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor. Inhibits tumor cell growth.