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IID00685
UniprotQ9UL40
ProteinZinc finger protein 346
GeneZNF346
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
xml
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
294
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 168-227 Monomer :
 Evidence NMR 2mkd A Reference
       Region 2mkd A 168-227 order
       Region 2mkd A 168-185 high_rmsd
       Region 2mkd A 196-211 high_rmsd
       Region 2mkd A 223-227 high_rmsd
 Evidence NMR 2mkn A Reference
       Region 2mkn A 168-180 disorder
       Region 2mkn A 181-224 order
       Region 2mkn A 225-227 disorder
Seqacetylation
    1-1 N-acetylmethionine
 
Prediction
NeProc
Disorder 1-67,94-234,262-294
Order 68-93,235-261
ProS 1-21,31-49,56-57,94-108,125-158,183-194,262-268,290-294
AlphaFold
Disorder 1-51,108-133,166-184,223-237,266-294
Order 52-107,134-165,185-222,238-265
SEG 118-132
Function
Function in SwissProt
Binds with low affinity to dsDNA and ssRNA, and with high affinity to dsRNA, with no detectable sequence specificity (PubMed:24521053). May bind to specific miRNA hairpins (PubMed:28431233).