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IID00703
 UniprotP08567
ProteinPleckstrin
GenePLEK
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 xml
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
350
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-105 Monomer :
 Evidence NMR 1pls A Reference
       Region 1pls A 1-105 order
Seq 116-229 Monomer :
 Evidence NMR 1w4m A Reference
       Region 1w4m A 121-124 disorder
       Region 1w4m A 125-219 order
       Region 1w4m A 220-223 disorder
 Evidence NMR 2cso A Reference
       Region 2cso A 116-229 order
Seq 234-350 Monomer :
 Evidence NMR 1xx0 A Reference
       Region 1xx0 A 234-350 order
 Evidence NMR 1x05 A Reference
       Region 1x05 A 235-350 order
 Evidence X-RAY 1zm0 B Reference
       Region 1zm0 B 240-241 disorder
       Region 1zm0 B 242-301 order
       Region 1zm0 B 302-309 disorder
       Region 1zm0 B 310-347 order
       Region 1zm0 B 348-350 disorder
 Evidence X-RAY 1zm0 A Reference
       Region 1zm0 A 240-242 disorder
       Region 1zm0 A 243-301 order
       Region 1zm0 A 302-310 disorder
       Region 1zm0 A 311-347 order
       Region 1zm0 A 348-350 disorder
 Evidence X-RAY 2i5f A Reference
       Region 2i5f A 244-302 order
       Region 2i5f A 303-310 disorder
       Region 2i5f A 311-347 order
 Evidence X-RAY 2i5c C Reference
       Region 2i5c C 244-300 order
       Region 2i5c C 301-310 disorder
       Region 2i5c C 311-347 order
 Evidence X-RAY 2i5c B Reference
       Region 2i5c B 244-300 order
       Region 2i5c B 301-310 disorder
       Region 2i5c B 311-347 order
 Evidence X-RAY 2i5c A Reference
       Region 2i5c A 244-300 order
       Region 2i5c A 301-310 disorder
       Region 2i5c A 311-347 order
Seqphosphorylation
    113-113 Phosphoserine; by PKC
    117-117 Phosphoserine; by PKC
Seqacetylation
    64-64 N6-acetyllysine
 
Prediction
NeProc
Disorder 108-237
Order 1-107,238-350
ProS 126-130,150-177,187-237
AlphaFold
Disorder 1-2,107-123,204-206,227-238,283-283,302-311,349-350
Order 3-106,124-203,207-226,239-282,284-301,312-348
Pfam Hmmer
PF00169 5-101 1.3e-25
PF00610 136-219 1.3e-26
PF00169 245-347 5.4e-28
Function
Function in SwissProt
Major protein kinase C substrate of platelets.