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IID50032
 UniprotP13053
ProteinVitamin D3 receptor
GeneVdr
OrganismRattus norvegicus
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
423
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 116-164,212-423 Hetero dimer : IID50031Complex
 Evidence X-RAY 2zxn A Reference
       Region 2zxn A 116-122 disorder
       Region 2zxn A 123-159 order
       Region 2zxn A 160-164 disorder
       Region 2zxn A 212-217 disorder
       Region 2zxn A 218-420 order
       Region 2zxn A 421-423 disorder
 Evidence X-RAY 2zxm A Reference
       Region 2zxm A 116-122 disorder
       Region 2zxm A 123-159 order
       Region 2zxm A 160-164 disorder
       Region 2zxm A 212-217 disorder
       Region 2zxm A 218-420 order
       Region 2zxm A 421-423 disorder
 Evidence X-RAY 2zmj A Reference
       Region 2zmj A 116-122 disorder
       Region 2zmj A 123-159 order
       Region 2zmj A 160-164 disorder
       Region 2zmj A 212-217 disorder
       Region 2zmj A 218-420 order
       Region 2zmj A 421-423 disorder
 Evidence X-RAY 2zmi A Reference
       Region 2zmi A 116-120 disorder
       Region 2zmi A 121-159 order
       Region 2zmi A 160-164 disorder
       Region 2zmi A 212-217 disorder
       Region 2zmi A 218-420 order
       Region 2zmi A 421-423 disorder
 Evidence X-RAY 2zmh A Reference
       Region 2zmh A 116-122 disorder
       Region 2zmh A 123-159 order
       Region 2zmh A 160-164 disorder
       Region 2zmh A 212-217 disorder
       Region 2zmh A 218-420 order
       Region 2zmh A 421-423 disorder
 Evidence X-RAY 3afr A Reference
       Region 3afr A 116-122 disorder
       Region 3afr A 123-159 order
       Region 3afr A 160-164 disorder
       Region 3afr A 212-217 disorder
       Region 3afr A 218-420 order
       Region 3afr A 421-423 disorder
Seq 116-164,212-423 Hetero dimer :
 Evidence X-RAY 3vt8 A Reference
       Region 3vt8 A 116-122 disorder
       Region 3vt8 A 123-159 order
       Region 3vt8 A 160-164 disorder
       Region 3vt8 A 212-217 disorder
       Region 3vt8 A 218-278 order
       Region 3vt8 A 279-285 disorder
       Region 3vt8 A 286-420 order
       Region 3vt8 A 421-423 disorder
Seq 116-164,212-423 Hetero dimer :
 Evidence X-RAY 3vt6 A Reference
       Region 3vt6 A 116-122 disorder
       Region 3vt6 A 123-159 order
       Region 3vt6 A 160-164 disorder
       Region 3vt6 A 212-217 disorder
       Region 3vt6 A 218-420 order
       Region 3vt6 A 421-423 disorder
Seq 116-164,212-423 Hetero dimer : IID00082Complex
 Evidence X-RAY 5h1e A Reference
       Region 5h1e A 116-122 disorder
       Region 5h1e A 123-159 order
       Region 5h1e A 160-164 disorder
       Region 5h1e A 212-217 disorder
       Region 5h1e A 218-419 order
       Region 5h1e A 420-423 disorder
Seq 116-164,212-423 Hetero dimer :
 Evidence X-RAY 3vt3 A Reference
       Region 3vt3 A 116-159 order
       Region 3vt3 A 160-164 disorder
       Region 3vt3 A 212-217 disorder
       Region 3vt3 A 218-420 order
       Region 3vt3 A 421-423 disorder
Seq 116-164,212-423 Hetero dimer :
 Evidence X-RAY 3vt4 A Reference
       Region 3vt4 A 116-122 disorder
       Region 3vt4 A 123-159 order
       Region 3vt4 A 160-164 disorder
       Region 3vt4 A 212-217 disorder
       Region 3vt4 A 218-420 order
       Region 3vt4 A 421-423 disorder
Seq 116-164,212-423 Hetero dimer :
 Evidence X-RAY 2zl9 A Reference
       Region 2zl9 A 116-122 disorder
       Region 2zl9 A 123-159 order
       Region 2zl9 A 160-164 disorder
       Region 2zl9 A 212-218 disorder
       Region 2zl9 A 219-419 order
       Region 2zl9 A 420-423 disorder
Seq 116-164,212-423 Hetero dimer : IID00173Complex
 Evidence X-RAY 2zfx A Reference
       Region 2zfx A 116-122 disorder
       Region 2zfx A 123-159 order
       Region 2zfx A 160-164 disorder
       Region 2zfx A 212-217 disorder
       Region 2zfx A 218-421 order
       Region 2zfx A 422-423 disorder
 Evidence X-RAY 4ynk A Reference
       Region 4ynk A 116-122 disorder
       Region 4ynk A 123-159 order
       Region 4ynk A 160-164 disorder
       Region 4ynk A 212-218 disorder
       Region 4ynk A 219-421 order
       Region 4ynk A 422-423 disorder
 Evidence X-RAY 3wtq A Reference
       Region 3wtq A 116-122 disorder
       Region 3wtq A 123-159 order
       Region 3wtq A 160-164 disorder
       Region 3wtq A 212-217 disorder
       Region 3wtq A 218-420 order
       Region 3wtq A 421-423 disorder
 Evidence X-RAY 3wt7 A Reference
       Region 3wt7 A 116-122 disorder
       Region 3wt7 A 123-159 order
       Region 3wt7 A 160-164 disorder
       Region 3wt7 A 212-217 disorder
       Region 3wt7 A 218-420 order
       Region 3wt7 A 421-423 disorder
 Evidence X-RAY 3wt6 A Reference
       Region 3wt6 A 116-122 disorder
       Region 3wt6 A 123-159 order
       Region 3wt6 A 160-164 disorder
       Region 3wt6 A 212-217 disorder
       Region 3wt6 A 218-419 order
       Region 3wt6 A 420-423 disorder
 Evidence X-RAY 3wt5 A Reference
       Region 3wt5 A 116-122 disorder
       Region 3wt5 A 123-159 order
       Region 3wt5 A 160-164 disorder
       Region 3wt5 A 212-217 disorder
       Region 3wt5 A 218-420 order
       Region 3wt5 A 421-423 disorder
 Evidence X-RAY 3w5t A Reference
       Region 3w5t A 116-122 disorder
       Region 3w5t A 123-159 order
       Region 3w5t A 160-164 disorder
       Region 3w5t A 212-217 disorder
       Region 3w5t A 218-422 order
       Region 3w5t A 423-423 disorder
 Evidence X-RAY 3w5r A Reference
       Region 3w5r A 116-122 disorder
       Region 3w5r A 123-159 order
       Region 3w5r A 160-164 disorder
       Region 3w5r A 212-217 disorder
       Region 3w5r A 218-422 order
       Region 3w5r A 423-423 disorder
 Evidence X-RAY 3w5q A Reference
       Region 3w5q A 116-122 disorder
       Region 3w5q A 123-159 order
       Region 3w5q A 160-164 disorder
       Region 3w5q A 212-217 disorder
       Region 3w5q A 218-420 order
       Region 3w5q A 421-423 disorder
 Evidence X-RAY 3w5p A Reference
       Region 3w5p A 116-122 disorder
       Region 3w5p A 123-159 order
       Region 3w5p A 160-164 disorder
       Region 3w5p A 212-217 disorder
       Region 3w5p A 218-420 order
       Region 3w5p A 421-423 disorder
 Evidence X-RAY 3w0j A Reference
       Region 3w0j A 121-159 order
       Region 3w0j A 160-164 disorder
       Region 3w0j A 212-217 disorder
       Region 3w0j A 218-420 order
 Evidence X-RAY 3w0i A Reference
       Region 3w0i A 121-159 order
       Region 3w0i A 160-164 disorder
       Region 3w0i A 212-217 disorder
       Region 3w0i A 218-420 order
 Evidence X-RAY 3w0h A Reference
       Region 3w0h A 118-159 order
       Region 3w0h A 160-164 disorder
       Region 3w0h A 212-217 disorder
       Region 3w0h A 218-420 order
 Evidence X-RAY 3w0g A Reference
       Region 3w0g A 121-159 order
       Region 3w0g A 160-164 disorder
       Region 3w0g A 212-217 disorder
       Region 3w0g A 218-420 order
 Evidence X-RAY 3vrw A Reference
       Region 3vrw A 116-122 disorder
       Region 3vrw A 123-159 order
       Region 3vrw A 160-164 disorder
       Region 3vrw A 212-218 disorder
       Region 3vrw A 219-419 order
       Region 3vrw A 420-423 disorder
 Evidence X-RAY 3vrv A Reference
       Region 3vrv A 116-122 disorder
       Region 3vrv A 123-158 order
       Region 3vrv A 159-164 disorder
       Region 3vrv A 212-218 disorder
       Region 3vrv A 219-419 order
       Region 3vrv A 420-423 disorder
 Evidence X-RAY 3vru A Reference
       Region 3vru A 116-122 disorder
       Region 3vru A 123-158 order
       Region 3vru A 159-164 disorder
       Region 3vru A 212-218 disorder
       Region 3vru A 219-420 order
       Region 3vru A 421-423 disorder
 Evidence X-RAY 3vrt A Reference
       Region 3vrt A 116-123 disorder
       Region 3vrt A 124-159 order
       Region 3vrt A 160-164 disorder
       Region 3vrt A 212-217 disorder
       Region 3vrt A 218-419 order
       Region 3vrt A 420-423 disorder
 Evidence X-RAY 3vjt A Reference
       Region 3vjt A 116-122 disorder
       Region 3vjt A 123-158 order
       Region 3vjt A 159-164 disorder
       Region 3vjt A 212-218 disorder
       Region 3vjt A 219-420 order
       Region 3vjt A 421-423 disorder
 Evidence X-RAY 3vjs A Reference
       Region 3vjs A 116-122 disorder
       Region 3vjs A 123-158 order
       Region 3vjs A 159-164 disorder
       Region 3vjs A 212-218 disorder
       Region 3vjs A 219-421 order
       Region 3vjs A 422-423 disorder
 Evidence X-RAY 1rkh A Reference
       Region 1rkh A 116-122 disorder
       Region 1rkh A 123-159 order
       Region 1rkh A 160-164 disorder
       Region 1rkh A 212-217 disorder
       Region 1rkh A 218-422 order
       Region 1rkh A 423-423 disorder
 Evidence X-RAY 1rkg A Reference
       Region 1rkg A 116-122 disorder
       Region 1rkg A 123-159 order
       Region 1rkg A 160-164 disorder
       Region 1rkg A 212-217 disorder
       Region 1rkg A 218-421 order
       Region 1rkg A 422-423 disorder
 Evidence X-RAY 1rk3 A Reference
       Region 1rk3 A 116-122 disorder
       Region 1rk3 A 123-159 order
       Region 1rk3 A 160-164 disorder
       Region 1rk3 A 212-218 disorder
       Region 1rk3 A 219-420 order
       Region 1rk3 A 421-423 disorder
 Evidence X-RAY 1rjk A Reference
       Region 1rjk A 116-122 disorder
       Region 1rjk A 123-159 order
       Region 1rjk A 160-164 disorder
       Region 1rjk A 212-218 disorder
       Region 1rjk A 219-420 order
       Region 1rjk A 421-423 disorder
 Evidence X-RAY 2o4r A Reference
       Region 2o4r A 116-122 disorder
       Region 2o4r A 123-159 order
       Region 2o4r A 160-164 disorder
       Region 2o4r A 212-218 disorder
       Region 2o4r A 219-421 order
       Region 2o4r A 422-423 disorder
 Evidence X-RAY 2o4j A Reference
       Region 2o4j A 116-122 disorder
       Region 2o4j A 123-159 order
       Region 2o4j A 160-164 disorder
       Region 2o4j A 212-218 disorder
       Region 2o4j A 219-421 order
       Region 2o4j A 422-423 disorder
 Evidence X-RAY 5gid A Reference
       Region 5gid A 124-159 order
       Region 5gid A 160-164 disorder
       Region 5gid A 212-218 disorder
       Region 5gid A 219-419 order
 Evidence X-RAY 5gic A Reference
       Region 5gic A 124-158 order
       Region 5gic A 159-164 disorder
       Region 5gic A 212-218 disorder
       Region 5gic A 219-420 order
 Evidence X-RAY 5b5b D Reference
       Region 5b5b D 116-122 disorder
       Region 5b5b D 123-159 order
       Region 5b5b D 160-164 disorder
       Region 5b5b D 212-217 disorder
       Region 5b5b D 218-420 order
       Region 5b5b D 421-423 disorder
 Evidence X-RAY 5b5b A Reference
       Region 5b5b A 116-159 order
       Region 5b5b A 160-164 disorder
       Region 5b5b A 212-217 disorder
       Region 5b5b A 218-420 order
       Region 5b5b A 421-423 disorder
 Evidence X-RAY 5b41 A Reference
       Region 5b41 A 116-122 disorder
       Region 5b41 A 123-159 order
       Region 5b41 A 160-164 disorder
       Region 5b41 A 212-218 disorder
       Region 5b41 A 219-420 order
       Region 5b41 A 421-423 disorder
 Evidence X-RAY 5awk A Reference
       Region 5awk A 116-122 disorder
       Region 5awk A 123-159 order
       Region 5awk A 160-164 disorder
       Region 5awk A 212-217 disorder
       Region 5awk A 218-420 order
       Region 5awk A 421-423 disorder
 Evidence X-RAY 5awj A Reference
       Region 5awj A 116-122 disorder
       Region 5awj A 123-159 order
       Region 5awj A 160-164 disorder
       Region 5awj A 212-217 disorder
       Region 5awj A 218-420 order
       Region 5awj A 421-423 disorder
 Evidence X-RAY 3aun A Reference
       Region 3aun A 116-123 disorder
       Region 3aun A 124-159 order
       Region 3aun A 160-164 disorder
       Region 3aun A 212-217 disorder
       Region 3aun A 218-419 order
       Region 3aun A 420-423 disorder
 Evidence X-RAY 3a2h A Reference
       Region 3a2h A 116-122 disorder
       Region 3a2h A 123-158 order
       Region 3a2h A 159-164 disorder
       Region 3a2h A 212-218 disorder
       Region 3a2h A 219-421 order
       Region 3a2h A 422-423 disorder
Seq 116-164,212-423 Hetero dimer :
 Evidence X-RAY 2zlc A Reference
       Region 2zlc A 116-122 disorder
       Region 2zlc A 123-159 order
       Region 2zlc A 160-164 disorder
       Region 2zlc A 212-217 disorder
       Region 2zlc A 218-420 order
       Region 2zlc A 421-423 disorder
Seq 116-164,212-423 Hetero dimer :
 Evidence X-RAY 2zla A Reference
       Region 2zla A 116-122 disorder
       Region 2zla A 123-158 order
       Region 2zla A 159-164 disorder
       Region 2zla A 212-218 disorder
       Region 2zla A 219-420 order
       Region 2zla A 421-423 disorder
Seq 116-164,212-423 Hetero dimer :
 Evidence X-RAY 3vt7 A Reference
       Region 3vt7 A 116-122 disorder
       Region 3vt7 A 123-159 order
       Region 3vt7 A 160-164 disorder
       Region 3vt7 A 212-217 disorder
       Region 3vt7 A 218-277 order
       Region 3vt7 A 278-287 disorder
       Region 3vt7 A 288-420 order
       Region 3vt7 A 421-423 disorder
Seq 116-164,212-423 Hetero dimer :
 Evidence X-RAY 3vtc A Reference
       Region 3vtc A 116-122 disorder
       Region 3vtc A 123-159 order
       Region 3vtc A 160-164 disorder
       Region 3vtc A 212-217 disorder
       Region 3vtc A 218-420 order
       Region 3vtc A 421-423 disorder
Seq 116-164,212-423 Hetero dimer :
 Evidence X-RAY 3vt9 A Reference
       Region 3vt9 A 116-122 disorder
       Region 3vt9 A 123-159 order
       Region 3vt9 A 160-164 disorder
       Region 3vt9 A 212-217 disorder
       Region 3vt9 A 218-278 order
       Region 3vt9 A 279-285 disorder
       Region 3vt9 A 286-420 order
       Region 3vt9 A 421-423 disorder
Seq 116-164,212-423 Hetero dimer :
 Evidence X-RAY 3vtb A Reference
       Region 3vtb A 116-122 disorder
       Region 3vtb A 123-159 order
       Region 3vtb A 160-164 disorder
       Region 3vtb A 212-217 disorder
       Region 3vtb A 218-420 order
       Region 3vtb A 421-423 disorder
Seq 116-164,212-423 Hetero dimer :
 Evidence X-RAY 3vt5 A Reference
       Region 3vt5 A 116-122 disorder
       Region 3vt5 A 123-159 order
       Region 3vt5 A 160-164 disorder
       Region 3vt5 A 212-217 disorder
       Region 3vt5 A 218-420 order
       Region 3vt5 A 421-423 disorder
Seq 116-164,212-423 Hetero dimer :
 Evidence X-RAY 3vtd A Reference
       Region 3vtd A 116-122 disorder
       Region 3vtd A 123-159 order
       Region 3vtd A 160-164 disorder
       Region 3vtd A 212-217 disorder
       Region 3vtd A 218-420 order
       Region 3vtd A 421-423 disorder
Seq 117-164,212-419 Hetero tetramer : IID00173Complex
 Evidence X-RAY 5gie D Reference
       Region 5gie D 117-123 disorder
       Region 5gie D 124-156 order
       Region 5gie D 157-164 disorder
       Region 5gie D 212-218 disorder
       Region 5gie D 219-297 order
       Region 5gie D 298-301 disorder
       Region 5gie D 302-419 order
 Evidence X-RAY 5gie A Reference
       Region 5gie A 117-162 order
       Region 5gie A 163-164 disorder
       Region 5gie A 212-297 order
       Region 5gie A 298-300 disorder
       Region 5gie A 301-419 order
 
Prediction
NeProc
Disorder 1-21,103-218,421-423
Order 22-102,219-420
ProS 13-21,103-114,133-156,183-192,198-203
AlphaFold
Disorder 1-18,160-218,371-372,420-423
Order 19-159,219-370,373-419
Pfam Hmmer
PF00105 22-97 5.8e-47
PF00104 231-417 1.5e-47
SEG 102-114 ,171-190
Function
Function in SwissProt
Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells (PubMed:17227670). Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR (By similarity). The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes (By similarity). Plays a central role in calcium homeostasis (PubMed:17227670).