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IID50033
 UniprotP17133
ProteinU1 small nuclear ribonucleoprotein 70 kDa
GenesnRNP-U1-70K
OrganismDrosophila melanogaster
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
448
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 405-425 Hetero dimer : Q7JPS0
 Evidence NMR 2bn5 B Reference
       Region 2bn5 B 405-425 order
       Region 2bn5 B 405-412 high_rmsd
       Region 2bn5 B 424-425 high_rmsd
 
Prediction
NeProc
Disorder 70-73,188-317,346-448
Order 1-69,74-187,318-345
ProS 70-73,188-219,230-236,272-280,349-356,364-395,401-437,443-448
AlphaFold
Disorder 1-1,203-205,207-220,222-222,228-314,350-418,420-448
Order 2-202,206-206,221-221,223-227,315-349,419-419
Pfam Hmmer
PF00076 104-175 6.3e-24
SEG 60-75 ,185-202 ,211-239 ,248-350 ,397-402
Function
Function in SwissProt
Mediates the splicing of pre-mRNA by binding to the stem loop I region of U1-snRNA (PubMed:15611175). Required during oogenesis for nurse cell chromatin dispersal (PubMed:24244416).