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IID50043
 UniprotP25801
ProteinRhombotin-2
GeneLmo2
OrganismMus musculus
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
158
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 26-87 Monomer : IID50049Complex
 Evidence NMR 1j2o A Reference
       Region 1j2o A 26-87 order
       Region 1j2o A 26-26 high_rmsd
       Region 1j2o A 63-71 high_rmsd
       Region 1j2o A 87-87 high_rmsd
Seq 84-156 Hetero dimer : IID50040Complex,IID50049Complex
 Evidence NMR 2l6y B Reference
       Region 2l6y B 84-156 order
       Region 2l6y B 84-88 high_rmsd
Seq 84-156 Monomer : IID50049Complex
 Evidence NMR 2lxd A Reference
       Region 2lxd A 84-91 order
       Region 2lxd A 84-90 high_rmsd
       Region 2lxd A 92-93 disorder
       Region 2lxd A 94-96 order
       Region 2lxd A 97-98 disorder
       Region 2lxd A 99-102 order
       Region 2lxd A 103-106 disorder
       Region 2lxd A 107-155 order
       Region 2lxd A 156-156 disorder
Seq 84-156 Hetero trimer : IID50040Complex,IID50049Complex
 Evidence NMR 2l6z C Reference
       Region 2l6z C 84-156 order
       Region 2l6z C 84-88 high_rmsd
 
Prediction
NeProc
Disorder 1-26,154-158
Order 27-153
ProS 154-158
AlphaFold
Disorder 1-11,158-158
Order 12-157
Pfam Hmmer
PF00412 30-89 1.3e-13
PF00412 94-153 9.4e-23
Function
Function in SwissProt
Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state.