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IID50050
UniprotQ06505
ProteinTranscription factor SPN1
GeneSPN1
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c)
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
410
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 141-310 Monomer :
 Evidence X-RAY 3o8z A Reference
       Region 3o8z A 148-295 order
 Evidence X-RAY 3nfq B Reference
       Region 3nfq B 141-147 disorder
       Region 3nfq B 148-290 order
       Region 3nfq B 291-310 disorder
 Evidence X-RAY 3nfq A Reference
       Region 3nfq A 141-147 disorder
       Region 3nfq A 148-294 order
       Region 3nfq A 295-310 disorder
Seq 148-292 Hetero dimer : IID50042Complex
 Evidence X-RAY 3oak B Reference
       Region 3oak B 148-292 order
 Evidence X-RAY 3oak A Reference
       Region 3oak A 148-292 order
Seqphosphorylation
    89-89 Phosphoserine
    86-86 Phosphothreonine
    85-85 Phosphoserine
    40-40 Phosphoserine
    23-23 Phosphoserine; by ATM or ATR
    15-15 Phosphothreonine
 
Prediction
NeProc
Disorder 1-151,305-410
Order 152-304
ProS 4-14,126-134,147-151,305-313,351-378,386-402
AlphaFold
Disorder 1-122,137-144,304-304,310-310,326-344,375-395,408-410
Order 123-136,145-303,305-309,311-325,345-374,396-407
Pfam Hmmer
PF05909 156-410 3.8e-36
SEG 192-205 ,351-362
Function
Function in SwissProt
Transcription factor involved in RNA polymerase II transcription regulation. May function in both SPT15/TBP post-recruitment and recruitment steps of transcription.