Search Keyword:


Search option:


IID50062
 UniprotO89100
ProteinGRB2-related adaptor protein 2
GeneGrap2
OrganismMus musculus
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
322
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 50-147 Homo tetramer :
 Evidence X-RAY 1r1p A Reference
       Region 1r1p A 50-52 disorder
       Region 1r1p A 53-147 order
 Evidence X-RAY 1r1p B Reference
       Region 1r1p B 50-147 order
 Evidence X-RAY 1r1p C Reference
       Region 1r1p C 50-147 order
 Evidence X-RAY 1r1p D Reference
       Region 1r1p D 50-52 disorder
       Region 1r1p D 53-147 order
Seq 50-147 Monomer :
 Evidence X-RAY 1r1s G Reference
       Region 1r1s G 50-147 order
 Evidence X-RAY 1r1s E Reference
       Region 1r1s E 50-147 order
 Evidence X-RAY 1r1s C Reference
       Region 1r1s C 50-51 disorder
       Region 1r1s C 52-147 order
 Evidence X-RAY 1r1s A Reference
       Region 1r1s A 50-51 disorder
       Region 1r1s A 52-147 order
 Evidence X-RAY 1r1q B Reference
       Region 1r1q B 50-147 order
 Evidence X-RAY 1r1q A Reference
       Region 1r1q A 50-50 disorder
       Region 1r1q A 51-147 order
Seq 263-322 Hetero dimer : IID00318Complex
 Evidence NMR 1h3h A Reference
       Region 1h3h A 263-322 order
Seq 265-322 Hetero dimer : IID50090Complex
 Evidence X-RAY 1oeb B Reference
       Region 1oeb B 265-266 disorder
       Region 1oeb B 267-321 order
       Region 1oeb B 322-322 disorder
 Evidence X-RAY 1oeb A Reference
       Region 1oeb A 265-319 order
       Region 1oeb A 320-322 disorder
Seq 265-322 Hetero dimer : IID50083Complex
 Evidence X-RAY 1uti A Reference
       Region 1uti A 265-321 order
       Region 1uti A 322-322 disorder
Seq 265-322 Hetero dimer : IID50093Complex
 Evidence X-RAY 2w10 B Reference
       Region 2w10 B 265-322 order
 Evidence X-RAY 2w10 A Reference
       Region 2w10 A 265-321 order
       Region 2w10 A 322-322 disorder
Seq 267-322 Hetero tetramer :
 Evidence X-RAY 2d0n C Reference
       Region 2d0n C 267-321 order
       Region 2d0n C 322-322 disorder
 Evidence X-RAY 2d0n A Reference
       Region 2d0n A 267-322 order
Seqphosphorylation
    254-254 Phosphothreonine
    230-230 Phosphoserine
    186-186 Phosphoserine
    45-45 Phosphotyrosine
Seqacetylation
    106-106 N6-acetyllysine
 
Prediction
NeProc
Disorder 156-258
Order 1-155,259-322
ProS 156-240,255-258
AlphaFold
Disorder 31-31,148-264,322-322
Order 1-30,32-147,265-321
Pfam Hmmer
PF00018 1-54 5e-18
PF00017 58-132 6.7e-28
PF00018 266-320 2.4e-21
SEG 193-216
Function
Function in SwissProt
Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc.